scholarly journals Physicians' communication of risks from non-steroidal anti-inflammatory drugs and attitude towards providing adverse drug reaction information to patients

2017 ◽  
Vol 23 (6) ◽  
pp. 1387-1394 ◽  
Author(s):  
Pacharaporn Phueanpinit ◽  
Juraporn Pongwecharak ◽  
Sermsak Sumanont ◽  
Janet Krska ◽  
Narumol Jarernsiripornkul
Keyword(s):  
Adverse Drug Reaction ◽  
Drug Reaction ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

scholarly journals Amoxicillin induced toxic epidermal necrolysis

2020 ◽  
Vol 9 (3) ◽  
pp. 510
Author(s):  
Lakshmi Narasimha G. ◽  
Kalpana P.
Keyword(s):  
Adverse Drug Reaction ◽  
Drug Reaction ◽  
Toxic Epidermal Necrolysis ◽  
Broad Spectrum ◽  
Beta Lactam ◽  
Beta Lactams ◽  
Beta Lactam Antibiotic ◽  
Lactam Antibiotic ◽  
Life Threatening ◽  
Inflammatory Drugs

Toxic epidermal necrolysis (TEN) is a rare life-threatening adverse drug reaction associated with mucocutaneous eruptions and peeling of skin (sloughing) mostly caused by drugs like sulphonamides, beta lactams, carbamazepine and non-steroidal anti-inflammatory drugs (NSAIDs). Amoxicillin is a broad spectrum, bactericidal, Beta-lactam antibiotic used in treatment of various infections. Here by we have reported the case of amoxicillin induced severe toxic epidermal necrolysis. A Patient admitted in the hospital with the symptoms of epidermal sloughing that resulted in bare dermis as he received Amoxicillin drug for his diagnosis of fever. After clear examination TEN was confirmed and suspected with the cause due to Amoxicillin. The drug was stopped and patient was treated with other drugs for symptomatic cure. The patient was recovered from his condition and improved significantly.

A Brief review of medicinal properties of Vacha (Acorus calamus Linn.) from Nighantus

2017 ◽  
Vol 2 (3) ◽  
Author(s):  
Yogita Tilavat ◽  
Rekha Parmar
Keyword(s):  
Adverse Drug Reaction ◽  
Drug Reaction ◽  
Acorus Calamus ◽  
Herbal Drugs ◽  
Herbal Drug ◽  
Chronological Order ◽  
The People ◽  
Medicinal Properties ◽  
Synthetic Drug ◽  
Anti Inflammatory

Herbs and herbal drugs have created interest among the people by the clinical proven effect like anti-inflammatory, analgesic, antipyretic, immunomodulations and adaptogenic. Also the overuse of synthetic drug, which results in higher incidence of adverse drug reaction, has motivated humans to return to nature for safer remedies. In this review we have taken Vacha (Acorus calamus Linn.) The present work aims to discuss Vacha in various Nighantus as manuscripts or just as evidence - in a chronological order. It is important herbal drug in various aspect like, Acorus calamus Linn. has also been used successfully by some Ayurvedic practitioners for Krimi, Sthaulya, Vibandha, Unmada, Apasmara etc

scholarly journals Causality Assessment of Adverse Drug Reaction Using Naranjo Probability Scale: A Retrospective Study

2020 ◽  
Vol 19 (1) ◽  
pp. 16-19
Author(s):  
Sangha Ratna Bajracharya ◽  
Rakesh Ghimire ◽  
Pradip Gyanwali ◽  
Anjan Khadka
Keyword(s):  
Adverse Drug Reaction ◽  
Drug Reaction ◽  
Antimicrobial Agents ◽  
Causality Assessment ◽  
Tertiary Care ◽  
Probability Scale ◽  
Information Unit ◽  
Naranjo Algorithm ◽  
Inflammatory Drugs ◽  
Relationship Of

Introduction: Globally, Adverse Drug Reaction (ADR) has been listed as the sixth leading causes of death. Recognition of ADR and establishment of relationship of drug with the symptom is the first step to the management of the problem. In this study, Naranjo algorithm has been used which is one of the most accepted tools for the assessment of causality of ADR with the suspected drug. Methods: A retrospective descriptive study was done which included 35 reported cases of ADRs in Drug Information Unit (DIU) in tertiary care teaching institute of Nepal from Dec 2015 to Oct 2016. Based on the information in the reported ADRs forms, categorisation was done using Naranjo’s ADR Probability scale. The data was analysed using SPSS version 16.0 and descriptive statistics was used. Results: It was seen that ADRs were more common in male (n=20) as compared to female (n=15). Amongst male, ADRs were more common in age group 50-75 years (n=8). ADRs were most commonly seen with antimicrobial agents (40%) followed by Non-Steroidal Anti-inflammatory Drugs (NSAIDs) (20%) and immunosuppressants (20%). Within the antimicrobial agents, anti-tubercular drugs (20%) contributed the most in ADRs and hepatotoxicity was the most common ADR seen. Majority of ADRs were categorised under possible (n=29) followed by probable (n=6). Conclusions: Naranjo algorithm could be a useful tool for causality assessment of ADR which can help physicians to guide the therapy.

Polyphenols from Cymbopogon citratus inhibit iNOS expression and NO production – a promising source of new anti-inflammatory drugs

Planta Medica ◽  
2010 ◽  
Vol 76 (12) ◽  
Author(s):  
V Francisco ◽  
A Figueirinha ◽  
B Neves ◽  
C Garcia-Rodriguez ◽  
M Lopes ◽  
...  
Keyword(s):  
Inos Expression ◽  
No Production ◽  
Cymbopogon Citratus ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Promising Source

Heparin and proteoglycans as anti-inflammatory drugs

1996 ◽  
Vol 16 (01) ◽  
pp. 56-59
Author(s):  
D. J. Tyrrell ◽  
C. P. Page
Keyword(s):  
Inflammatory Diseases ◽  
Therapeutic Applications ◽  
Wide Range ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

SummaryEvidence continues to accumulate that the pleiotropic nature of heparin (beyond its anticoagulant potency) includes anti-inflammatory activities at a number of levels. It is clear that drugs exploiting these anti-inflammatory activities of heparin may offer exciting new therapeutic applications to the treatment of a wide range of inflammatory diseases.

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