The Relationship between Polypharmacy and Physical Activity in Those with or at Risk of Knee Osteoarthritis

Objectives. We compared mindsets about physical activity among those with and without knee osteoarthritis and investigated if these mindsets relate to physical activity level and symptom management. Methods. Participants with (n=150) and without (n=152) knee osteoarthritis completed an online survey at study enrollment (T1). Participants with knee osteoarthritis repeated the survey three weeks later (T2; n=62). The mindset questionnaire, scored from 1-4, assessed the extent to which individuals associate the process of exercising with less appeal-focused qualities (e.g., boring, painful, isolating, and depriving) vs. appeal-focused (e.g., fun, pleasurable, social, and indulgent) versus. Using linear regression, we examined the relationship between mindset and having knee osteoarthritis, and, in the subgroup of participants with knee osteoarthritis, the relationship between mindset at T1 and physical activity (via the Physical Activity Scale for the Elderly) at T2. We also compared mindsets between those who use medication for management and those who use exercise. Results. A less appeal-focused mindset regarding physical activity was marginally associated with having knee osteoarthritis (β=-0.125, P=0.096). Within the knee osteoarthritis group, a more appeal-focused mindset predicted higher future physical activity (β=20.68, P=0.039), controlling for current physical activity, demographics, and health. Individuals that used exercise with or without pain medication or injections had more appeal-focused process mindsets than those who used medication or injections without exercise (P<0.001). Further, the process mindset inventory demonstrated strong internal consistency (α=0.92 at T1 for n=150 and α=0.92 at T2 for n=62) and test-retest reliability (ICC>0.841, P<0.001) within the knee osteoarthritis population. Conclusion. In individuals with knee osteoarthritis, mindsets predict future physical activity levels and relate to an individual's management strategy. Mindsets are a reliable and malleable construct and may be a valuable target for increasing physical activity and improving adherence to rehabilitation strategies involving exercise among individuals with knee osteoarthritis.

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P1-653: UNDERSTANDING THE RELATIONSHIP BETWEEN PHYSICAL ACTIVITY, DEPRESSIVE SYMPTOMS AND SLEEP QUALITY IN OLDER ADULTS AT-RISK FOR DEMENTIA

Alzheimer s & Dementia ◽

10.1016/j.jalz.2018.06.665 ◽

2006 ◽

Vol 14 (7S_Part_10) ◽

pp. P592-P592

Author(s):

Danit Saks ◽

Sharon L. Naismith ◽

Haley LaMonica ◽

Loren Mowszowski ◽

Jonathon Pye ◽

...

Keyword(s):

Physical Activity ◽

Older Adults ◽

At Risk ◽

Depressive Symptoms ◽

Sleep Quality ◽

The Relationship

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Physical Activity is Strongly Inversely Related To Post-Challenge Plasma Glucose and Glycemic Spikes in a Risk Population for Type 2 Diabetes

Folia Medica ◽

10.2478/folmed-2013-0015 ◽

2013 ◽

Vol 55 (2) ◽

pp. 33-42 ◽

Cited By ~ 1

Author(s):

Theodora Temelkova-Kurktschiev ◽

Tsvetan Stefanov ◽

Carsta Koehler ◽

Elena Henkel ◽

Frank Schaper ◽

...

Keyword(s):

Physical Activity ◽

Risk Factors ◽

Type 2 Diabetes ◽

At Risk ◽

Glucose Tolerance ◽

Plasma Glucose ◽

Cardiometabolic Risk ◽

Post Challenge ◽

The Relationship

ABSTRACT AIM: To examine the relationship between physical activity (PA) and various cardiometabolic risk factors during an oral glucose tolerance test (OGTT), including glycemic spikes (PGS) in individuals at risk for type 2 diabetes. SUBJECTS AND METHODS: A total of 949 middle-aged subjects from the Risk factors in Impaired Glucose Tolerance for Atherosclerosis and Diabetes (RIAD) trial aged 40-70 years were included in the present cross-sectional analysis. Standard 75 g OGTT was performed and blood was collected every 30 min for 2 hours for measurements of plasma glucose (PG) and other cardiometabolic risk factors. PA was assessed using interviewer-administered questionnaire. RESULTS: Post-challenge PGS and maximal PG (PGmax) during OGTT were significantly lower in individuals with high PA vs. individuals with low PA even after body mass index (BMI) adjustment (p = 0.026 and p = 0.035, respectively). In univariate analysis post-challenge PG 30, 60, 90, and 120 minutes, PGS and PGmax during OGTT were significantly inversely correlated to PA. This correlation was attenuated but remained significant after adjustment for BMI. Fasting PG and glycosylated hemoglobin were not correlated to PA. Significantly higher fasting and post-challenge insulin levels were found among subjects with low vs. subjects with medium (p < 0.05) and high PA (p < 0.05). Post-challenge C-peptide and proinsulin levels were significantly lower in participants with high vs. participants with low PA (p < 0.05 for all). The relationship between 2-h PG and PA was observed also in lean subjects and in subjects with normal fasting glucose. In multivariate analysis PA was a significant independent determinant of 2-h PG. CONCLUSION: We found a strong inverse relationship between PA and various post-challenge cardiometabolic parameters during OGTT, including glycemic spikes, in a population at risk for diabetes. This relationship was only partially dependent on BMI.

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Influence of Educational Level on Psychosocial Correlates and Perceived Environmental Correlates of Physical Activity in Adults at Risk for Type 2 Diabetes: The Feel4Diabetes-Study

Journal of Physical Activity and Health ◽

10.1123/jpah.2019-0003 ◽

2019 ◽

Vol 16 (12) ◽

pp. 1105-1112 ◽

Cited By ~ 1

Author(s):

Nele Huys ◽

Vicky Van Stappen ◽

Samyah Shadid ◽

Marieke De Craemer ◽

Odysseas Androutsos ◽

...

Keyword(s):

Physical Activity ◽

Type 2 Diabetes ◽

At Risk ◽

Environmental Factors ◽

Educational Level ◽

Diabetes Risk ◽

Analysis Of Covariance ◽

Environmental Correlates ◽

The Relationship

Background: This study aimed to investigate whether the relationship between psychosocial and perceived environmental factors and physical activity (PA) in adults at risk for type 2 diabetes is influenced by educational level. Methods: Based on the Finnish Diabetes Risk Score questionnaire, this study selected 164 adults (Mage: 38 (5.34) y, 13.4% men) at type 2 diabetes risk from 11 low socioeconomic neighborhoods in Flanders (Belgium). Participants filled out questionnaires on psychosocial and perceived environmental factors and wore an ActiGraph accelerometer for 5 consecutive days. Statistical analyses were performed using analysis of covariance in SPSS. Results: Educational level significantly influenced the association between perception of body weight and light PA (P = .01) and total PA (P = .03) on weekend days. Educational level did not influence the associations between other psychosocial and perceived environmental factors (ie, perceived social influence; environmental, time and attitudinal barriers, perceived self-efficacy; knowledge and fatalism) and PA. Conclusions: Educational level did not influence the relationship between most psychosocial and perceived environmental factors and PA in this sample of adults at type 2 diabetes risk. This suggests that addressing different psychosocial and perceived environmental correlates in lower and higher educated participants might not be necessary. However, more research in this specific population is needed.

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