The Relationship of Frailty and Hospitalization Among Older People: Evidence From a Meta-Analysis

2018 ◽  
Vol 50 (4) ◽  
pp. 383-391 ◽  
Author(s):  
Shu-Fang Chang ◽  
Hsiang-Chun Lin ◽  
Chih-Ling Cheng
Keyword(s):  
Older People ◽  
Meta Analysis ◽  
Relationship Of ◽  
The Relationship

HUBUNGAN KONDISI FISIK, PSIKOLOGIS, DAN SOSIAL LANJUT USIA DENGAN DISABILITAS FUNGSIONAL LANJUT USIA DI YOGYAKARTA

2017 ◽  
Vol 16 (1) ◽  
Author(s):  
Catur Hary Wibawa
Keyword(s):  
Older People ◽  
Physical Condition ◽  
Social Condition ◽  
Psychological Condition ◽  
High Category ◽  
Correlational Design ◽  
Functional Disabilities ◽  
Relationship Of ◽  
Spearman Test ◽  
The Relationship

Abstract This research aims to reveal 1. the condition of older people who lives in Plosokerep Shleter, 2. the psychological condition of older people in Plosokerep Shelter, 3. the social condition of older people in Plosokerep Shelter, 4. the relationship of physical condition experienced by older people with their functional disabilities in Plosokerep Shelter, 5. the relationship of psychological condition experienced by older people with their functional disabilities in Plosokerep Shleter, 6. to know the relatonship of social condition experienced by older people with their functional disabilities in Plosokerep Shelter. The research method used is explanatory-analytic correlational design, to examine the relationship of factors: Physical (X1 variable), Psychological (X2), and social (X3) with older people functional disabilities (Y variable) descriptive survey used explanatory-analytic correlational design. Data collection carried out through questionnaire. Research data analysis used descriptive statistic technique with Spearman test statistic. The result showed that: 1. some older people in Plosokerep shleter have high physical condition and the rest of them in the low physical condition category, 2. from the psychological condition some of older people are in high category, 3. Social condition experienced by older people who live in shelter are in high category, 4. The relationship of physical condition experienced by older people in the shelter with functional disabilities even though there is a correlation but not significant, 5. the relationship of psychological condition experienced by older people in shleter with functional disabilities even though there is a correlation but not significant, 6. the relationship of social condition experienced by older people in the shelter with functional disabilities even though there is a correlation but not significant, 7. the relationship of Physical, psychological and social condition together with functional disabilities even though there is a correlation but not significant.Keywords: physical, psychological, and social condition, functional disabilities, older people Abstrak Penelitian ini bertujuan untuk mengungkapkan: 1. Mengetahui kondisi fisik lanjut usia yang ada di shelter Plosokerep, 2. Mengetahui kondisi psikologis lanjut usia yang ada di shelter Plosokerep, 3. Mengetahui kondisi sosial lanjut usia yang ada di shelter Plosokerep, 4. Mengetahui hubungan kondisi fisik yang dialami lanjut usia dengan disabilitas fungsionalnya selama tinggal di shelter Plosokerep, 5. Mengetahui hubungan kondisi psikologis yang dialami lanjut usia dengan disabilitas fungsionalnya selama tinggal di shelter Plosokerep, 6. Mengetahui hubungan kondisi sosial yang dialami lanjut usia dengan disabilitas fungsionalnya selama tinggal di shelter Plosokerep.Metode penelitian yang digunakan adalah disain korelasional eksplanatori-analitis, yaitu untuk menguji hubungan antara faktor-faktor: fisik (variabel X1), psikologis (X2), dan sosial (X3) dengan disabilitas fungsional lanjut usia (variabel Y)survey deskriptif dengan menggunakan disain penelitian korelasional eksplanatori-analitis. Teknik pengumpulan data dilakukan melalui kuesioner. Analisis data penelitian menggunakan teknik Statistik deskriptif, dengan statistik uji Spearman.Hasil penelitian menunjukkan bahwa: 1. Sebagian lanjut usia di shelter pengungsian Plosokerep memiliki kondisi fisik kategori tinggi, dan sebagian lagi berada dalam kondisi fisik kategori rendah, 2. Dilihat dari kondisi psikologis, sebagian besar lanjut usia berada dalam kategori tinggi, 3. Kondisi sosial yang dialami lanjut usia selama berada di shelter pengungsian, sebagian besar juga berada dalam kategori tinggi, 4. Hubungan kondisi fisik yang dialami lanjut usia selama berada di shelter pengungsian dengan disabilitas fungsional, meskipun terdapat korelasi tetapi tidak signifikan, 5. Hubungan kondisi psikologis yang dialami lanjut usia selama berada di shelter pengungsian dengan disabilitas fungsional, meskipun terdapat korelasi tetapi tidak signifikan, 6. Hubungan kondisi sosial yang dialami lanjut usia selama berada di shelter pengungsian dengan disabilitas fungsional, meskipun terdapat korelasi tetapi tidak signifikan, 7. Hubungan kondisi fisik, psikologis, dan sosial secara bersama-sama dengan disabilitas fungsional, meskipun terdapat korelasi tetapi tidak signifikan.Kata kunci:  disabilitas fungsional, kondisi fisik, psikologis, dan sosial, lanjut usia

scholarly journals Associations of CTLA4 Gene Polymorphisms with Graves’ Ophthalmopathy: A Meta-Analysis

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Pengfei Du ◽  
Xiaojie Ma ◽  
Changjiang Wang
Keyword(s):  
Genetic Model ◽  
Meta Analysis ◽  
Case Control Studies ◽  
Graves Ophthalmopathy ◽  
Increased Risk ◽  
Exon 1 ◽  
Ctla4 Gene ◽  
Relationship Of ◽  
The Relationship ◽  
Susceptible Gene

Many studies have established that T-lymphocyte antigen-4 (CTLA4) is a susceptible gene for Graves’ disease (GD). Also many studies showed the association between the CTLA4 exon-1 49A/G polymorphism and the risk of developing Graves’ ophthalmopathy (GO) in GD patients. But those results were inconsistent. In recent years many new studies were published which helped to shed light on the relationship of CTLA4 SNP49 with GO. So we performed the meta-analysis to explore the association between the SNP49 and GO susceptibility in GD patients. Studies up to February 29, 2012, were searched by using PubMed. The odds ratio was used to evaluate the strength of the association. Altogether 12 case-control studies involving 2,505 participants were included in the meta-analysis. Results showed that the G allele was related to the increased risk of GO compared with the A allele under allelic genetic model (OR = 1.14, 95% CI: 1.14–1.72,P=0.001) in European subgroup. No publication bias was detected. Our results showed that the SNP49 polymorphism of CTLA4 gene was related to increased risk of GO.

scholarly journals Serum IGF1, metabolic syndrome, and incident cardiovascular disease in older people: a population-based study

2013 ◽  
Vol 168 (3) ◽  
pp. 393-401 ◽  
Author(s):  
Christa C van Bunderen ◽  
Mirjam M Oosterwerff ◽  
Natasja M van Schoor ◽  
Dorly J H Deeg ◽  
Paul Lips ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Older People ◽  
Population Based ◽  
Mortality Data ◽  
The Metabolic Syndrome ◽  
Longitudinal Aging Study Amsterdam ◽  
Aging Study ◽  
Definition Of ◽  
Relationship Of ◽  
The Relationship

ObjectiveHigh as well as low levels of IGF1 have been associated with cardiovascular diseases (CVD). The relationship of IGF1 with (components of) the metabolic syndrome could help to clarify this controversy. The aims of this study were: i) to investigate the association of IGF1 concentration with prevalent (components of) the metabolic syndrome; and ii) to examine the role of (components of) the metabolic syndrome in the relationship between IGF1 and incident CVD during 11 years of follow-up.MethodsData were used from the Longitudinal Aging Study Amsterdam, a cohort study in a representative sample of the Dutch older population (≥65 years). Data were available in 1258 subjects. Metabolic syndrome was determined using the definition of the US National Cholesterol Education Program Adult Treatment Panel III. CVD were ascertained by self-reports and mortality data.ResultsLevels of IGF1 in the fourth quintile were associated with prevalent metabolic syndrome compared with the lowest quintile (odds ratio: 1.59, 95% confidence interval (CI) 1.09–2.33). The middle up to the highest quintile of IGF1 was positively associated with high triglycerides in women. Metabolic syndrome was not a mediator in the U-shaped relationship of IGF1 with CVD. Both subjects without the metabolic syndrome and low IGF1 levels (hazard ratio (HR) 1.75, 95% CI 1.12–2.71) and subjects with the metabolic syndrome and high IGF1 levels (HR 2.28, 95% CI 1.21–4.28) demonstrated increased risks of CVD.ConclusionsIn older people, high-normal IGF1 levels are associated with prevalent metabolic syndrome and high triglycerides. Furthermore, this study suggests the presence of different pathomechanisms for both low and high IGF1 levels and incident CVD.

scholarly journals Low birth weight, preterm birth and small for gestational age association with adult depression: systematic review and meta-analysis

2014 ◽  
Vol 205 (5) ◽  
pp. 340-347 ◽  
Author(s):  
Christian Loret De Mola ◽  
Giovanny Vinícius Araújo De França ◽  
Luciana de Avila Quevedo ◽  
Bernardo Lessa Horta
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Gestational Age ◽  
Premature Birth ◽  
Fixed Effects ◽  
Meta Analysis ◽  
Adult Depression ◽  
Meta Analyses ◽  
Relationship Of ◽  
The Relationship

BackgroundThere is no consensus on the effects that low birth weight, premature birth and intrauterine growth have on later depression.AimsTo review systematically the evidence on the relationship of low birth weight, smallness for gestational age (SGA) and premature birth with adult depression.MethodWe searched the literature for original studies assessing the effect of low birth weight, premature birth and SGA on adult depression. Separate meta-analyses were carried out for each exposure using random and fixed effects models. We evaluated the contribution of methodological covariates to heterogeneity using meta-regression.ResultsWe identified 14 studies evaluating low birth weight, 9 premature birth and 4 SGA. Low birth weight increased the odds of depression (OR = 1.39, 95% CI 1.21–1.60). Premature birth and SGA were not associated with depression, but publication bias might have underestimated the effect of the former and only four studies evaluated SGA.ConclusionsLow birth weight was associated with depression. Future studies evaluating premature birth and SGA are needed.

Genetic mediation in the relationship of education to cognitive function in older people.

1995 ◽  
Vol 10 (1) ◽  
pp. 48-53 ◽  
Author(s):  
Dorit Carmelli ◽  
Gary E. Swan ◽  
Lon R. Cardon
Keyword(s):  
Cognitive Function ◽  
Older People ◽  
Relationship Of ◽  
The Relationship

Genetic variants of PEAR1 and ischemic clinical outcomes in coronary artery disease patients: a systematic review and meta-analysis

2021 ◽  
Author(s):  
Xinyi Zhang ◽  
Sicong Li ◽  
Yuxuan Zhao ◽  
Ningjia Tang ◽  
Tong Jia ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Clinical Outcomes ◽  
Odds Ratio ◽  
Meta Analysis ◽  
Electronic Database ◽  
Artery Disease ◽  
Relationship Of ◽  
The Relationship ◽  
Ischemic Events

Aim: The aim of this study was to assess the association between PEAR1 polymorphisms and ischemic clinical outcomes. Materials & methods: We searched the electronic database for articles on the relationship of PEAR1 SNPs and ischemic events in patients with coronary artery disease (CAD) up to October 2020. Results: A total of 9914 patients with CAD from six studies focusing on 12 SNPs of PEAR1 were included in this study. The A allele of rs12041331 were associated with ischemic events (odds ratio: 1.40; 95% CI: 1.04–1.88; p = 0.03). The AA homozygotes of rs2768759 was related to a higher risk of ischemic events than carriers of the C allele (odds ratio: 2.08; 95% CI: 1.09–3.97; p = 0.03). Conclusion: PEAR1 rs12041331 and rs2768759 are significantly associated with ischemic events in patients with CAD.

scholarly journals Relationship of Obstructive Sleep Apnoea with Diabetic Retinopathy: A Meta-Analysis

2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Zhenliu Zhu ◽  
Fengying Zhang ◽  
Yunxia Liu ◽  
Shuqin Yang ◽  
Chunting Li ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Sensitivity Analysis ◽  
Diabetic Retinopathy ◽  
Publication Bias ◽  
Meta Analysis ◽  
Sleep Apnoea ◽  
Obstructive Sleep ◽  
Increased Risk ◽  
Relationship Of ◽  
The Relationship

Until now, the relationship of obstructive sleep apnoea (OSA) with diabetic retinopathy (DR) was controversial. This meta-analysis was performed to obtain definitive conclusion on this topic. Relevant articles were searched on databases of Pubmed, Google Scholar, and Chinese National Knowledge Infrastructure (CNKI). The articles were selected according to inclusion and exclusion criteria. Odds ratio (OR) with 95% confidence interval (CI) was used to evaluate the relationship of OSA with risk of DR.I2andPvalue were used to assess the presence of heterogeneity.I2≥ 50% orP<0.05indicated significant heterogeneity. Sensitivity analysis was performed to evaluate the robustness of pooled results. Begg’s funnel plot and Egger’s regression analysis were adopted to assess publication bias. 6 eligible studies were selected in the present meta-analysis. The pooled results indicated that OSA was significantly associated with increased risk of DR (OR = 2.01, 95% CI = 1.49–2.72). Subgroup analysis based on type of diabetes mellitus suggested that OSA was related to DR in both Type 1 and Type 2 diabetes mellitus. Sensitivity analysis demonstrated that pooled results were robust. No significant publication bias was observed (P=0.128). The results indicate that OSA is related to increased risk of DR.

The Relationship of Children’s Intelligence Quotient and Blood Lead and Zinc Levels: a Meta-analysis and System Review

2017 ◽  
Vol 182 (2) ◽  
pp. 185-195 ◽  
Author(s):  
Yu Wu ◽  
Jiantao Sun ◽  
Minsheng Wang ◽  
Guangxia Yu ◽  
Liping Yu ◽  
...  
Keyword(s):  
Intelligence Quotient ◽  
Meta Analysis ◽  
Blood Lead ◽  
Lead And Zinc ◽  
System Review ◽  
Zinc Levels ◽  
Relationship Of ◽  
The Relationship

scholarly journals The Relationship of Coronary Artery Calcium and Clinical Coronary Artery Disease with Cognitive Function: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 27 (9) ◽  
pp. 934-958 ◽  
Author(s):  
Congying Xia ◽  
Marleen Vonder ◽  
Grigory Sidorenkov ◽  
Matthijs Oudkerk ◽  
Jan Cees de Groot ◽  
...  
Keyword(s):  
Systematic Review ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Cognitive Function ◽  
Coronary Artery Calcium ◽  
Meta Analysis ◽  
Artery Disease ◽  
Relationship Of ◽  
The Relationship
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