Ultraviolet radiation exposure and serum vitamin D levels in young children

The article is devoted to the study of features of clinical course of atopic dermatitis and vitamin D exchange in young children conducted by us by estimation of severity of atopic dermatitis depending on the value of SCORAD index, determination of 25(OH)D concentration in serum of children by immunochemical method with chemocentric analysis according to the classification approved by experts of the international endocrinological society. In the examination of 188 young children, two groups were formed on the basis of the Lviv City Children's Clinical Hospital. Children from 1 month to 1 year of age with manifestations of atopic dermatitis (n = 120), who were born full-term and had no birth defects, metabolic disorders, severe perinatal CNS lesions formed the main group. The comparison group consisted of 68 healthy young children without chronic diseases. All children had atopic dermatitis in the main group and were classified by severity (depending on the SCORAD index): children with mild severity – 31 (26 %), moderate 47 (39 %), and severe 42 (35 %). As a result of the study, we found a association between the severity of clinical manifestations of atopic dermatitis and the level of vitamin D in the serum. Comparative analysis of the severity of atopic dermatitis, depending on the level of vitamin D in the serum, showed that with severe atopic dermatitis in children of the main group, the level of 25(OH)D was significantly lower compared to its indicators in children with moderate to severe (P < 0.05). Serum vitamin D levels are significantly lower in all forms of atopic dermatitis severity and correlate significantly with the overall SCORAD severity score, erythema intensity, excoriation, itching, and sleep disturbances. The scientific data on the presence of feedback correlation (r = –0,48; P < 0,05) between the development of atopic dermatitis in children and their level of 25(OH)D in serum were added. Our findings suggest that there is a need for a differentiated approach to treating early-stage atopic dermatitis of varying severity, a personalized therapeutic approach to choosing a vitamin D supplementation, given the level of 25(OH)D in the serum.

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Investigation of Vitamin D Levels in Children Aged 0–4 Years in Yunnan Province

10.21203/rs.3.rs-418111/v1 ◽

2021 ◽

Author(s):

Yuqin Wu ◽

Yanfei Yang ◽

Xiao Xiao ◽

Lin Wang ◽

Zheng Yin ◽

...

Keyword(s):

Vitamin D ◽

Young Children ◽

Yunnan Province ◽

Serum Vitamin ◽

Policy Formulation ◽

Vitamin D Supplementation ◽

Serum Vitamin D ◽

Vitamin D Levels ◽

Significant Difference ◽

Infants And Young Children

Abstract Aim: To investigate the vitamin D levels in children aged 0–4 years in Yunnan Province.Methods: This study selected children aged 0 to 4 years who underwent physical examination in the special needs clinic of the Hospital from October 2019 to December 2020 as subjects to analyze serum 25(OH)D levels.Result: Vitamin D deficiency was more common in girls than in boys. There was no significant difference in serum vitamin D levels between boys and girls at any age. However, there was a significant decrease in vitamin D levels after 2 years old in all chidren at all ages. The levels of vitamin D in children were highest in summer, which were significantly higher than other seasons, and were lowest in winter. At the same time, vitamin D levels were significantly different based on the economic level of cities. The serum vitamin D contents of infants and young children in the top five cities with the highest economic levels were significantly higher than in lower-ranked cities. There was a significant correlation between vitamin D content and serum calcium. Conclusion: This study preliminarily determined a reasonable reference range for serum 25 hydroxyvitamin D content in infants aged 0–4 years in Yunnan Province. Which will be of significance for the establishment of official guidelines on vitamin D supplementation in infants and young children in Yunnan and for policy formulation.

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Serum Vitamin D Levels and Skeletal and General Development of Young Bearded Dragon Lizards (Pogona vitticeps), underDifferent Conditions of UV-B Radiation Exposure

Journal of Animal and Veterinary Advances ◽

10.3923/javaa.2011.229.234 ◽

2011 ◽

Vol 10 (2) ◽

pp. 229-234 ◽

Cited By ~ 4

Author(s):

K.R. Kroenlein ◽

K.L. Zimmerman ◽

G. Saunders ◽

S.D. Holladay

Keyword(s):

Vitamin D ◽

Radiation Exposure ◽

Serum Vitamin ◽

General Development ◽

Serum Vitamin D ◽

Vitamin D Levels ◽

Bearded Dragon ◽

Pogona Vitticeps

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Clinical factors correlated with vitamin D deficiency in patients with obesity scheduled for bariatric surgery: A single center experience

International Journal for Vitamin and Nutrition Research ◽

10.1024/0300-9831/a000662 ◽

2020 ◽

Vol 90 (3-4) ◽

pp. 346-352

Author(s):

Vincenzo Pilone ◽

Salvatore Tramontano ◽

Carmen Cutolo ◽

Federica Marchese ◽

Antonio Maria Pagano ◽

...

Keyword(s):

Bariatric Surgery ◽

Vitamin D ◽

Vitamin D Deficiency ◽

Serum Vitamin ◽

Inverse Correlation ◽

Model Assessment ◽

Cross Sectional ◽

Serum Vitamin D ◽

Female Sex ◽

Vitamin D Levels

Abstract. We aim to assess the prevalence of vitamin D deficiency (VDD) in patients scheduled for bariatric surgery (BS), and to identify factors that might be associated with VDD. We conducted a cross-sectional observational study involving all consecutive patients scheduled for BS from 2017 to 2019. The exclusion criteria were missing data for vitamin D levels, intake of vitamin D supplements in the 3 months prior to serum vitamin D determination, and renal insufficiency. A total of 206 patients (mean age and body mass index [BMI] of 34.9 ± 10.7 years, and 44.3 ± 6.99 kg/m2, respectively) met the inclusion criteria and were enrolled for data analysis. VDD (<19.9 ng/mL), severe VDD (<10 ng/mL), and vitamin D insufficiency (20–29.9 ng/mL) were present in 68.8 %, 12.5 %, and 31.2 % of patients, respectively. A significant inverse correlation was found between vitamin D levels and initial BMI, parathyroid hormone, and homeostatic model assessment of insulin resistance (r = −0.280, p < 0.05; r = −0.407, p = 0.038; r = −0.445, p = 0.005), respectively. VDD was significantly more prevalent in patients with higher BMI [−0.413 ± 0.12, CI95 % (−0.659; −0.167), p = 0.006], whereas no significant association between hypertension [−1.005 ± 1.65, CI95 % (−4.338; 2.326), p = 0.001], and diabetes type 2 (T2D) [−0.44 ± 2.20, CI95 % (−4.876; 3.986), p = 0.841] was found. We observed significant association between female sex and levels of vitamin D [6.69 ± 2.31, CI95 % (2.06; 11.33), p = 0.006]. The present study shows that in patients scheduled for BS, VDD deficiency is common and was associated with higher BMI, and female sex.

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Maternal Serum Vitamin D Levels During Pregnancy and Offspring Neurocognitive Development

PEDIATRICS ◽

10.1542/peds.2011-2644d ◽

2012 ◽

Vol 129 (3) ◽

pp. X11-X11

Keyword(s):

Vitamin D ◽

Serum Vitamin ◽

Maternal Serum ◽

Neurocognitive Development ◽

Serum Vitamin D ◽

Vitamin D Levels

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Faculty Opinions recommendation of Decreased serum vitamin D levels in children with asthma are associated with increased corticosteroid use.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.3437965.3141061 ◽

2010 ◽

Author(s):

Leonard Bacharier ◽

Avraham Beigelman

Keyword(s):

Vitamin D ◽

Serum Vitamin ◽

Serum Vitamin D ◽

Vitamin D Levels ◽

Children With Asthma

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Association of Vitamin D Levels and Other Risk Factors with Asthma Exacerbations in Children

Pakistan Journal of Medicine and Dentistry ◽

10.36283/pjmd9-4/004 ◽

2020 ◽

Keyword(s):

Risk Factors ◽

Vitamin D ◽

Serum Vitamin ◽

Persistent Asthma ◽

Food Allergies ◽

P Value ◽

Serum Vitamin D ◽

Asthma Exacerbations ◽

Vitamin D Levels ◽

Animal Dander

Background: The risk factors for asthma exacerbations are well understood. However, the effect of vitamin D levels on number of asthma exacerbations per year is not clearly studied. The objective of the study was to ﬁnd out the association of serum vitamin D levels and asthma risk factors on asthma exacerbations. Methods: In this study, ninety-nine subjects from 5 to 15 years of age were recruited at an episode of acute exacerbation. It was a cross sectional study and carried out from 2012 to 2015. Pulmonary function test was done by spirometry. Asthma exacerbation was labeled when forced expiratory volume/ forced vital capacity (FEV1/FVC) ratio was less than 80% (American Thoracic Society). Global Initiative for Asthma (GINA) guidelines were used to classify asthma into mild, moderate and severe persistent asthma. Serum vitamin D levels were measured by chemiluminescence method. Pearson Chi-square test was applied and p value (p<0.05) was considered as statistically signiﬁcant. Results: Children who had exposure to animal dander had signiﬁcantly lower asthma exacerbations per year (p-value <0.046). There was no signiﬁcant association between vitamin D levels and number of exacerbations per years (p-value <0.099). Asthma was prevalent in girls of low socioeconomic status (SES) compared to males. However, there was no signiﬁcant association between smoke, exercise, home environment, food allergies, weather, pollen and dust with asthma exacerbations. Conclusion: Low levels of vitamin D were not associated with increased number of asthma exacerbations per year. However, children exposed to animal dander had lesser number of exacerbations per year (p-value <0.046). Keywords: Asthma; Vitamin D; Children; Exacerbations, Risk factors.

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