Curcumin‐loaded Pluronic ® F‐127 Micelles as a Drug Delivery System for Curcumin‐mediated Photodynamic Therapy for Oral Application

2021 ◽  
Author(s):  
Diego Dantas Lopes dos Santos ◽  
João Felipe Besegato ◽  
Priscila Borges Gobbo de Melo ◽  
João Augusto Oshiro Junior ◽  
Marlus Chorilli ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Photodynamic Therapy ◽  
Drug Delivery System ◽  
Delivery System ◽  
Oral Application

Researches on Preparation of Photosan Loaded Magnetic Silica Anoparticles and their Anti-Tumor Effects in Photodynamic Therapy

2012 ◽  
Vol 622-623 ◽  
pp. 821-826
Author(s):  
Yu Wen ◽  
Xiao Feng Deng ◽  
Liang Liang Liu ◽  
Shu Yun Shi ◽  
Li Xiong
Keyword(s):  
Drug Delivery ◽  
Photodynamic Therapy ◽  
Drug Delivery System ◽  
Delivery System ◽  
Sol Gel ◽  
Haematoporphyrin Derivative ◽  
X Ray Diffraction ◽  
Transmission Electron ◽  
Good Biocompatibility ◽  
Low Solubility

Photodynamic therapy (PDT) is an effective, noninvasive and nontoxic therapeutics for cancer and some other diseases. It is becoming a alternative of traditional therapeutics for cancers. But the efficacy of PDT was restricted by insufficient selectivity and low solubility. In this study, novel multifunctional silica-based magnetic nanoparticles were prepared as targeting drug delivery system to achieve higher specificity and better solubility. Haematoporphyrin derivative (photosan) was used as photosensitizer. Magnetite nanoparticles (Fe3O4) and photosan were incorporated in silica nanoparticles by microemulsion and sol-gel methods. The prepared nanoparticles were characterized by X-ray diffraction, and transmission electron microscopy. The nanoparticles possessed good biocompatibility and could cause remarkable photodynamic anti-tumor effects. These suggested that photosan-Fe3O4 nanoparticles had great potential as effective drug delivery system in targeting photodynamic therapy.

scholarly journals Enhanced effect of photodynamic therapy in ovarian cancer using a nanoparticle drug delivery system

2015 ◽  
Vol 47 (3) ◽  
pp. 1070-1076 ◽  
Author(s):  
ZHAO LI ◽  
LIPING SUN ◽  
ZAIJUN LU ◽  
XUANTAO SU ◽  
QIFENG YANG ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Drug Delivery ◽  
Photodynamic Therapy ◽  
Drug Delivery System ◽  
Delivery System ◽  
Nanoparticle Drug Delivery

Magnetic chitosan nanoparticles as a drug delivery system for targeting photodynamic therapy

2009 ◽  
Vol 20 (13) ◽  
pp. 135102 ◽  
Author(s):  
Yun Sun ◽  
Zhi-long Chen ◽  
Xiao-xia Yang ◽  
Peng Huang ◽  
Xin-ping Zhou ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Photodynamic Therapy ◽  
Drug Delivery System ◽  
Delivery System ◽  
Chitosan Nanoparticles ◽  
Magnetic Chitosan

scholarly journals Bacterial Cellulose Membranes as a Potential Drug Delivery System for Photodynamic Therapy of Skin Cancer

2016 ◽  
Author(s):  
Maristela de F. S. Peres ◽  
Karina Nigoghossian ◽  
Fernando L. Primo ◽  
Sybele Saska ◽  
Ticiana S. de O. Capote ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Photodynamic Therapy ◽  
Skin Cancer ◽  
Bacterial Cellulose ◽  
Drug Delivery System ◽  
Delivery System ◽  
Potential Drug ◽  
Cellulose Membranes

Oxygen self-sufficient fluorinated polypeptide nanoparticles for NIR imaging-guided enhanced photodynamic therapy

2018 ◽  
Vol 6 (15) ◽  
pp. 2323-2331 ◽  
Author(s):  
Pan Yuan ◽  
Zheng Ruan ◽  
Wei Jiang ◽  
Le Liu ◽  
Jiaxiang Dou ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Photodynamic Therapy ◽  
Drug Delivery System ◽  
Delivery System ◽  
High Efficiency ◽  
Water Dispersible ◽  
Nir Imaging

Oxygen self-sufficient fluorinated polypeptide nanoparticles have been synthesized via the loading of a NIR photosensitizer (BODIPY-Br2) into a water-dispersible drug delivery system for high efficiency PDT.

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