Redundant roles of four ZIP family members in zinc homeostasis and seed development in Arabidopsis thaliana

2021 ◽  
Author(s):  
Sichul Lee ◽  
Joohyun Lee ◽  
Felipe K. Ricachenevsky ◽  
Tracy Punshon ◽  
Ryan Tappero ◽  
...  
Keyword(s):  
Arabidopsis Thaliana ◽  
Seed Development ◽  
Family Members ◽  
Zinc Homeostasis ◽  
Zip Family

scholarly journals Function, Structure, and Transport Aspects of ZIP and ZnT Zinc Transporters in Immune Cells

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Bum-Ho Bin ◽  
Juyeon Seo ◽  
Sung Tae Kim
Keyword(s):  
Immune Cells ◽  
Drug Targets ◽  
Therapeutic Potential ◽  
Family Members ◽  
Zinc Transporter ◽  
Zinc Homeostasis ◽  
Zinc Transporters ◽  
Function Structure ◽  
Rich Domain ◽  
Zip Family

Zinc is an important trace metal in immune systems, and zinc transporters are involved in many immune responses. Recent advances have revealed the structural and biochemical bases for zinc transport across the cell membrane, with clinical implications for the regulation of zinc homeostasis in immune cells like dendritic cells, T cells, B cells, and mast cells. In this review, we discuss the function, structure, and transport aspects of two major mammalian zinc transporter types, importers and exporters. First, Zrt-/Irt-like proteins (ZIPs) mediate the zinc influx from the extracellular or luminal side into the cytoplasm. There are 14 ZIP family members in humans. They form a homo- or heterodimer with 8 transmembrane domains and extra-/intracellular domains of various lengths. Several ZIP members show specific extracellular domains composed of two subdomains, a helix-rich domain and proline-alanine-leucine (PAL) motif-containing domain. Second, ZnT (zinc transporter) was initially identified in early studies of zinc biology; it mediates zinc efflux as a counterpart of ZIPs in zinc homeostasis. Ten family members have been identified. They show a unique architecture characterized by a Y-shaped conformation and a large cytoplasmic domain. A precise, comprehensive understanding of the structures and transport mechanisms of ZIP and ZnT in combination with mice experiments would provide promising drug targets as well as a basis for identifying other transporters with therapeutic potential.

The amino acid permease AAP8 is important for early seed development in Arabidopsis thaliana

Planta ◽  
2007 ◽  
Vol 226 (4) ◽  
pp. 805-813 ◽  
Author(s):  
Roberto Schmidt ◽  
Harald Stransky ◽  
Wolfgang Koch
Keyword(s):  
Arabidopsis Thaliana ◽  
Amino Acid ◽  
Seed Development ◽  
Amino Acid Permease ◽  
Early Seed Development

scholarly journals The role of ZIP proteins in zinc assimilation and distribution in plants: current challenges

2019 ◽  
Vol 55 (No. 2) ◽  
pp. 45-54 ◽  
Author(s):  
Juan Daniel Lira-Morales ◽  
Nancy Varela-Bojórquez ◽  
Magaly Berenice Montoya-Rojo ◽  
J. Adriana Sañudo-Barajas
Keyword(s):  
Family Members ◽  
Zn Deficiency ◽  
Mineral Concentration ◽  
Regulation Of Expression ◽  
Zip Family ◽  
Zn Homeostasis ◽  
Homeostasis Regulation ◽  
Zn Status ◽  
Nutritional Imbalance

Soils with mineral deficiencies lead to nutritional imbalance in crops worldwide. Zinc (Zn) is a micronutrient that is fundamental for plant growth and development, being essential for the proper functioning of a range of enzymes and transcription factors. Zn transporters tightly regulate Zn homeostasis. Plants contain a large number of Zn-responsive genes that are specifically expressed under Zn deficiency to ensure the coordination of assimilatory pathways and meet the physiological requirements. This review brings together a range of studies that have been undertaken to investigate the effects of Zn status on the regulatory mechanisms involved in plant mineral nutrition. The ZIP (ZRT, IRT-like Protein) family is especially implicated in Zn transport and in the maintenance of cellular Zn homeostasis. Regulation of expression in relation to plant tissue, mineral concentration, and species has been determined for several ZIP family members. In the omic era, genomic and proteomic approaches have facilitated a rapid increase in our understanding of the roles of ZIP family members and their regulation, though significant knowledge gaps remain. A comprehensive understanding of ZIP proteins could lead to many potential molecular applications to improve crop management and food quality.  

scholarly journals Inflorescence Meristem Fate Is Dependent on Seed Development and FRUITFULL in Arabidopsis thaliana

2019 ◽  
Vol 10 ◽  
Author(s):  
Vicente Balanzà ◽  
Irene Martínez-Fernández ◽  
Shusei Sato ◽  
Martin F. Yanofsky ◽  
Cristina Ferrándiz
Keyword(s):  
Arabidopsis Thaliana ◽  
Seed Development ◽  
Inflorescence Meristem

scholarly journals Fertilization-independent seed development in Arabidopsis thaliana

1997 ◽  
Vol 94 (8) ◽  
pp. 4223-4228 ◽  
Author(s):  
A. M. Chaudhury ◽  
L. Ming ◽  
C. Miller ◽  
S. Craig ◽  
E. S. Dennis ◽  
...  
Keyword(s):  
Arabidopsis Thaliana ◽  
Seed Development

scholarly journals In Vivo Inhibition of Seed Development and Reserve Protein Accumulation in Recombinants of Abscisic Acid Biosynthesis and Responsiveness Mutants in Arabidopsis thaliana

1989 ◽  
Vol 90 (2) ◽  
pp. 463-469 ◽  
Author(s):  
Maarten Koornneef ◽  
Corrie J. Hanhart ◽  
Henk W. M. Hilhorst ◽  
Cees M. Karssen
Keyword(s):  
Arabidopsis Thaliana ◽  
Abscisic Acid ◽  
Seed Development ◽  
Protein Accumulation ◽  
Acid Biosynthesis ◽  
Abscisic Acid Biosynthesis ◽  
Reserve Protein

scholarly journals A role for LORELEI, a putative glycosylphosphatidylinositol-anchored protein, in Arabidopsis thaliana double fertilization and early seed development

2010 ◽  
Vol 62 (4) ◽  
pp. 571-588 ◽  
Author(s):  
Tatsuya Tsukamoto ◽  
Yuan Qin ◽  
Yiding Huang ◽  
Damayanthi Dunatunga ◽  
Ravishankar Palanivelu
Keyword(s):  
Arabidopsis Thaliana ◽  
Seed Development ◽  
Double Fertilization ◽  
Early Seed Development
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