High rate of seromarkers for HIV, HBV and syphilis among blood donors using confidential unit exclusion, before and after HIV‐NAT implementation at a major public blood bank in the Brazilian Amazon

Transfusion ◽  
2018 ◽  
Vol 59 (2) ◽  
pp. 629-638 ◽  
Author(s):  
Janaina C. Souza ◽  
Myuki A. E. Crispim ◽  
Claudia Abrahim ◽  
Nelson A. Fraiji ◽  
Dagmar Kiesslich ◽  
...  
Keyword(s):  
Blood Donors ◽  
Brazilian Amazon ◽  
Blood Bank ◽  
High Rate ◽  
Before And After

SEROPREVALENCE OF HIV AND HBsAg AMONGST BLOOD DONORS IN A TERTIARY CARE HOSPITAL, CHHATTISGARH.

2019 ◽  
Vol 3 (8) ◽  
Author(s):  
Anusha P ◽  
Bankar Nandkishor J ◽  
Karan Jain ◽  
Ramdas Brahmane ◽  
Dhrubha Hari Chandi
Keyword(s):  
Hepatitis B ◽  
Blood Donors ◽  
Hepatitis B Surface Antigen ◽  
Tertiary Care ◽  
Laboratory Diagnosis ◽  
Blood Bank ◽  
Care Hospital ◽  
Medical College ◽  
The World ◽  
First Time

INTRODUCTION: India being the second highly populated nation in the world. HIV/AIDS has acquired pandemic proportion in the world. Estimate by WHO for current infection rate in Asia. India has the third largest HIV epidemic in the world. HIV prevalence in the age group 15-49 yrs was an estimate of 0.2%. India has been classified as an intermediate in the Hepatitis B Virus (HBV) endemic (HBsAg carriage 2-7%) zone with the second largest global pool of chronic HBV infections. Safety assessment of the blood supply, the quality of screening measures and the risk of transfusion transmitted infectious diseases (TTIs) in any country can be estimated by scrutinizing the files of blood donors. After the introduction of the blood banks and improved storage facilities, it became more extensively used. Blood is one of the major sources of TTIs like hepatitis B, hepatitis C, HIV, syphilis, and many other blood borne diseases. Disclosure of these threats brought a dramatic change in attitude of physicians and patients about blood transfusion. The objective of this study is to determine the seroprevalence of transfusion transmitted infections amidst voluntary blood donors at a rural tertiary healthcare teaching hospital in Chhattisgarh. MATERIAL AND METHODS: This retrospective study was carried out in Chandulal Chandrakar Memorial Medical College, Kachandur, Durg. Blood donors were volunteers, or and commercial donors who donated the blood and paid by patients, their families, or friends to replace blood used or expected to be used for patients from the blood bank of the hospital. After proper donation of blood routine screening of blood was carried out according to standard protocol. Laboratory diagnosis of HIV 1 and HIV 2 was carried out by ELISA test. Hepatitis B surface antigen was screened by using ELISA. RESULTS: A total of 1915 consecutive blood donors’ sera were screened at Chandulal Chandrakar Memorial Medical College, blood bank during study period. Of these 1914 were male and 1 female. The mean age of patients was found to be 29.34 years with standard deviation (SD) of 11.65 Years. Among all blood donors in present study, 759(39.63%) were first time donors and 1156(60.37%) were repeated donors. 1 patient was HIV positive in first donation group while 3 (75%) were positive in repeat donation group. 7 (38.9%) were HBsAg positive in in first donation group while 11(61.1%) were positive in repeat donation group. Two patients in first donation group had dual infection of HIV and HBsAg. CONCLUSION: Seropositivity was high in repeated donors as compared to first time donors. The incidence of HIV is observed to be 0.2% and that of HBsAg is 0.94%. Strict selection of blood donors should be done to avoid transfusion-transmissible infections during the window period.

Seroprevalence and geographical distribution of sero‐positive blood donors toTrypanosoma cruziat the central blood bank of the National Medical Center “La Raza”

Transfusion ◽  
2018 ◽  
Vol 59 (2) ◽  
pp. 639-647 ◽  
Author(s):  
Saúl González‐Guzmán ◽  
Vladimir Paredes‐Cervantes ◽  
Bagu Tshima Edward ◽  
José A. Crescencio‐Trujillo ◽  
Ángel Guerra‐Marquez ◽  
...  
Keyword(s):  
Geographical Distribution ◽  
Blood Donors ◽  
Medical Center ◽  
Blood Bank ◽  
National Medical

scholarly journals Glasgow coma scale in acute poisonings before and after use of antidote in patients with history of use of psychotropic agents

2010 ◽  
Vol 138 (3-4) ◽  
pp. 210-213 ◽  
Author(s):  
Tonka Poplas-Susic ◽  
Zalika Klemenc-Ketis ◽  
Marija Komericki-Grzinic ◽  
Janko Kersnik
Keyword(s):  
Glasgow Coma Scale ◽  
Prescription Drugs ◽  
Drug Users ◽  
Acute Poisoning ◽  
Illegal Drug ◽  
High Rate ◽  
Illegal Drugs ◽  
Coma Scale ◽  
Before And After ◽  
History Of Use

Introduction. Data on emergency interventions in poisonings are scarce. Objective. To determine the effectiveness of antidote therapy in acute poisoning-related emergency medical services (EMS) interventions. Methods. A prospective observational study included all poisoning-related intervention cases over 3 years (1999-2001) in the Celje region, Slovenia, covering 125,000 inhabitants. Data were recorded on an EMS form. Results. Psychoactive agents were present in 56.5% out of 244 poisoning-related EMS interventions. Prescription drugs were a cause of intoxication in 93 (39.2%) cases alone or in combination with alcohol or illegal drugs. More than one fifth of poisonings were due to the use of illegal drugs in 52 (21.9%) cases, 43 (18.1%) out of them heroin related. At the time of EMS arrival, more patients who ingested illegal drugs were in coma or comatose than the rest. 24 (45.3%) vs. 32 (17.3%) of poisoned patients were in coma (p<0.001). Glasgow Coma Scale (GCS) at the first contact was lower in patients who ingested illegal drugs than in the remaining patients (9.0 vs. 11.6, p=0.001). In 23.2% of the cases, an antidote was administered. In 29 (12.2%) naloxone and in 16 (6.7%) flumazenil was administered. Mean GCS after intervention was higher in all cases but significantly higher in illegal drug cases, 13.4 vs. 12.2 (p=0.001), with a mean positive change in GCS of 4.5 vs. 0.6 (p<0.001). In illegal drug users, mean change after antidote administration was 8.2 vs. 0.5 without antidote administration (p<0.001). Conclusion. High rate of successful antidote use during the intervention indicated the importance of good EMS protocols and the presence of a skilled doctor in the EMS team.

scholarly journals Scientometrics analysis of recent trends in Global Corona virus Research

2020 ◽  
Author(s):  
Krishnamurthy M ◽  
Bhalachandra S Deshpande ◽  
Sajana C
Keyword(s):  
Web Of Science ◽  
Recent Literature ◽  
High Rate ◽  
Research Progress ◽  
Research Papers ◽  
Medical Virology ◽  
Before And After ◽  
Virus Research ◽  
Recent Trends ◽  
Prolific Authors

Abstract Background: The worldwide pandemic COVID-19 has produced a wealth of research more rapidly after the outbreak. In just a couple of months, there is a rise in several studies on Coronavirus, adding up to the scholarly literature.Method: The current study attempts to Scientometric analyze very recent literature on Coronaviruses just before and after the outbreak. Besides, the objective of this exploration was to assess the global research progress on Coronavirus in recent times. The current research is an analytical descriptive study using Scientometrics. The study sample includes research papers about the Coronavirus indexed in Web of Science (WoS) database from January 1, 2019 to May 14, 2020. The records with topic search (includes Title, Abstract, Keywords and Keywords Plus) “coronavirus” were extracted. These data were analyzed by MS Excel and the visualizations were created using TableauResult: The results showed that 2551 scientific literature about the Coronavirus was indexed in WoS. A considerable number of these articles were published in journals such as the Journal of Medical Virology, Viruses, Nature, and Lancet. Authors from China, USA and Italy were the most prolific authors. About 47.51% articles received total of 11435 citations with an average of 9 citations, which indicates that nearly half articles were cited in another publication. The highest and lowest citations for these articles were 737 and 1, respectively.Conclusion: These results show a high rate of research on Coronavirus.

scholarly journals Blood Transfusion Service and Hospital Blood Rotation: The Implications on Transfusion Safety in Nigeria

2019 ◽  
Vol 2 (1) ◽  
pp. 19-24
Author(s):  
O D Damulak ◽  
E D Jatau ◽  
E Ekam ◽  
E Rumji ◽  
R Yakubu ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
Diagnostic Test ◽  
Rapid Diagnostic Test ◽  
Blood Donors ◽  
Blood Donation ◽  
Tertiary Hospital ◽  
Sub Saharan Africa ◽  
High Rate ◽  
Blood Transfusion Service ◽  
First Time

Blood donation is not readily an altruistic sacrifice in sub-Saharan Africa where microbial infections, maternal haemorrhages, malaria and other tropical diseases that frequently require blood transfusion are daily diagnoses. Blood transfusion safety is hindered by the combined prevailing high rate of Transfusion-Transmissible Infections (TTIs) and poor screening techniques. This study determined the rate of Enzyme-Linked Immuno-Sorbent Assay (ELISA) positive reactions to transfusion-transmissible infections in rapid diagnostic test negative family replacement blood units, compared to the first time voluntarily donated blood. We studied records of blood units collected in a tertiary hospital from donors who scaled pre-donation Rapid diagnostic test (RDT) screening for the human immunodeficiency virus, hepatitis B and hepatitis C viruses and syphilis and rescreened by ELISA techniques at the National Blood Transfusion Service Centre in Jos, along with units from first-time voluntary blood donors. A total of 19562 blood units; 5945 (30.39%) rapid diagnostic tests negative from a linkage hospital and 13617 (69.61%) from first time voluntary donors were screened by ELISA methods for HIV, HBV, HCV, and syphilis. The overall TTIs detected by ELISA was 16.08%, significantly lower among pre-donation rapid screened family replacement blood donors [495(8.32%)] compared to 2651 (19.47%) among first-time voluntary donors; P=0.0001. Fifty-seven (0.96%) HIV, 166 (2.79%) HBV, 137 (2.31%) HCV and 137 (2.31%) syphilis were still detected respectively by ELISA in the pre-screened negative family replacement blood units. The outcome of ELISA screenings of blood collected from first-time volunteer donors were; 143 (1.05%) HIV, 1,486 (10.91%) HBV, 683 (5.02%) HCV, and 339 (2.49%) syphilis. Blood for transfusion should be screened negative at least with ELISA.

scholarly journals Assessing ABO/Rh Blood Group Frequency and Association with Asymptomatic Malaria among Blood Donors Attending Arba Minch Blood Bank, South Ethiopia

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Getaneh Alemu ◽  
Mohammedaman Mama
Keyword(s):  
Blood Group ◽  
Malaria Infection ◽  
Blood Donors ◽  
Blood Groups ◽  
High Rate ◽  
Abo Blood Group ◽  
Asymptomatic Malaria ◽  
Abo Blood Groups ◽  
Group Frequency ◽  
Rh Blood Group

Background. Determination of the various ABO/Rh blood group distributions and their association with malaria infection has paramount importance in the context of transfusion medicine and malaria control. Methods. Facility based cross-sectional study was conducted from February to June, 2015, to assess ABO/Rh blood groups distribution and their association with asymptomatic malaria. A structured questionnaire was used to collect data. Blood grouping was done using monoclonal antibodies. Thin and thick blood films were examined for Plasmodium parasites. Data were analyzed using SPSS version 20.0. Results. A total of 416 blood donors participated with median age of 22±0.29 (median ± standard error of the mean). Distribution of ABO phenotypes, in decreasing order, was O (175, 42.1%), A (136, 32.7%), B (87, 20.9%), and AB (18, 4.3%). Most of them were Rh+ (386, 92.8%). The overall malaria prevalence was 4.1% (17/416). ABO blood group is significantly associated with malaria infection (P=0.022). High rate of parasitemia was seen in blood group O donors (6.899, P=0.003) compared to those with other ABO blood groups. Conclusion. Blood groups O and AB phenotypes are the most and the least ABO blood groups, respectively. There is significant association between ABO blood group and asymptomatic malaria parasitemia.

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