The effect of time on packed cell volume following packed red blood cell transfusion in anemic dogs

Author(s):  
Jennifer L. Morris ◽  
Christopher P. Bloch ◽  
Tamera L. Brabson
2014 ◽  
Vol 83 (2) ◽  
pp. 145-149 ◽  
Author(s):  
Sheng Jiang ◽  
Hong-Gang Fan ◽  
De-Zhang Lu ◽  
Jin-Long Hou ◽  
Xu-Dong Song ◽  
...  

Oxidative stress in the body occurs when the production of free radicals overwhelms the antioxidant defence systems. The aim of this study was to examine the effects of a tiletamine/zolazepam-xylazine-tramadol combination on the antioxidant status, lipoperoxidase and blood cell indicators in eight miniature pigs. Baseline measures were recorded prior to anaesthesia, then the animals were anaesthetized with the combination of tiletamine/zolazepam (3.5 mg/kg), xylazine (1.32 mg/kg), and tramadol (1.8 mg/kg). Blood samples were collected from the anterior vena cava at 15, 30, 60, 90, 120 min, 24 h, and 72 h after anaesthesia. Plasma malondialdehyde, superoxide dismutase, catalase, and glutathione peroxidase concentrations were measured by colorimetry, and red blood cell counts, white blood cell counts, haemoglobin and packed cell volume were determined using an automated cell counter. The results showed that the concentration of malondialdehyde increased significantly at 30 and 60 min after the injection (P< 0.05), whereas glutathione peroxidase and catalase activity increased slightly (P> 0.05) then returned to baseline values after 90 min (P> 0.05). Superoxide dismutase activity increased significantly (P< 0.05) at 30 and 60 min, and then gradually decreased to baseline values after 90 min. Changes in red blood cell counts, haemoglobin and packed cell volume were not significant, while white blood cell count decreased significantly (P< 0.05) at 30 and 60 min. Our study is the first to demonstrate that tiletamine/zolazepam-xylazine-tramadol provide antioxidant effects, which may be proposed for alleviating the stress of examination and research at veterinary clinics or long-distance transportation.


2021 ◽  
Vol 13 ◽  
pp. 96-101
Author(s):  
B. I. Orji ◽  
G. C. Okeke ◽  
A. O. Akunjiyiba

The blood profile and the effects of age, sex and time of bleeding on the parameters were investigated in a 2x 2x 2 factorial experiment using twenty four guinea fowls (Numida meleagrs paths). The results show­ed that erythrocytes values were 2.43+0.04x 106/mm3, t packed cell volume, 37.44%; haerno0obin concentration (gm %), 13.17; etythrocyte sedimentation rate (mm/fir) 1.69; length of red blood cell, 12.89 microns width of P.BC, 6.63 microns, leucocyte count, 22.18+0.64x1031mrn3 and clotting time, 7.30 min. Sex anu sometimes age, time of bleeding and their interactions had signi­ficant effect on these haematological values. Correlations between these were calculated.


2007 ◽  
Vol 74 (1) ◽  
Author(s):  
P. Fandamu ◽  
T. Marcotty ◽  
J.R.A. Brandt ◽  
L. Duchateau ◽  
N. Speybroeck ◽  
...  

A comparison of mean corpuscular volume (MCV) and packed cell volume (PCV) was made between cattle undergoing lethal and non-lethal reactions following experimental infections with the apicomplexan protozoa, Theileria parva Katete. This work confirmed that anaemia occurs in infected animals. However, the fall in PCV was steeper in lethal reactions compared to non-lethal reactions. Our results show that animals with initially lower MCV values are more prone to fatal reaction, despite having normal PCV profiles. The study also found that small red blood cells are more likely to be infected with T. parva. These findings suggest that animals with a higher proportion of small red blood cells in circulation will be more likely to succumb to T. parva infections. The potential for using MCV as a predictor of the outcome of infection challenge is discussed.


2021 ◽  
Vol 42 (2) ◽  
pp. 88-93
Author(s):  
T. O. Adebowale ◽  
A. M. Bamgbose ◽  
A. O. Oso ◽  
Y. A. Adejola ◽  
F. K. Ola-Mudathir ◽  
...  

A 56-days experiment was carried out to study the effect of replacing macaroni waste meal (MWM) with maize on nutrient digestibility and blood chemistry of indigenous turkey starter. Ninety-six indigenous turkey poults with an average weight of 52 g were randomly assigned to four dietary treatments containing macaroni waste meal at 0%, 15%, 30% and 45% level as replacement for maize. Each treatment consist of 24 turkey poults replicated thrice with 8 turkeys per replicate. A three day metabolic study trial was carried out for nutrient digestibility determination. Blood samples were also collected for serum and haematological indices. Data collected were subjected to one way analysis of variance. Result showed that MWM at 15% had the highest values for packed cell volume, red blood cell, white blood cell while values recorded for serum uric acid and creatinine were significantly lower (P<0.05) for the turkeys. The nutrient digestibility coefficient such as crude protein digestibility, nitrogen retention were not affected significantly (P>0.05). However, the packed cell volume, red blood cell count, albumin, hemoglobin, total serum protein and serum glucose. It can be concluded that MWM could be incorporated into the diet of indigenous turkey starter at 15% level without any deleterious effect on nutrient digestibility and blood chemistry.


2010 ◽  
Vol 9 (2) ◽  
pp. 37
Author(s):  
A. Sh. Aliawy

Five adult female rabbits, their body weight is between 1.5-2 kg and their age ranges between 12-14 weeks along with 3 adult male for a probation.T he animal housed in hygienic conditions at arrival immediately check for pregnancy were found a negative (nonpregnant). After that rod was inserted in the vagina to induce puncture any part in the uterus or uterine horn to administer 3,3′ Diaminobenzidine. After 29 days agent test for pregnancy, there was found pregnant. Blood samples examined for hormonal and enzyme changes and for counting of red blood cell (RBC) white blood cell (WBC) packed cell volume(PCV) and ham globulin (Hb). There were a significant changes found in the blood values profess values and on vial the values of progesterone.


Author(s):  
Iserhienrhien Lucky Osafanme ◽  
Sheneni Victor Duniya ◽  
Nweje-Anyalowu Paul Chukwuemeka ◽  
Oguche Mercy ◽  
Idakwoji Precious Adejoh

Aim: The haematinic activity of the aqueous extract of Lophira lanceolata leaves was investigated using rat model of phenylhydrazine-induced anaemia. Methods and Results: Red Blood Cell (RBC) count, Haemoglobin (Hb) concentration and Packed Cell Volume (PCV) were analysed as indices of anaemia. Following phenylhydrazine administration to rats at a dose of 10 mg/kg for 8 days, a significant decrease (P<0.05) in the haematological parameters was observed indicating anaemia. However, treatment with graded doses (200, 400 and 800 mg/kg) of the aqueous extract of Lophira lanceolata leaves produced a significant (P<0.05) increase in the RBC count, Hb concentration and PCV time- and dose- dependently. Conclusion: It was concluded that Lophira lanceolata leaves possess haematinic activity, making it useful in the management of anaemia.


2017 ◽  
Vol 1 (2) ◽  
pp. 25
Author(s):  
Muhammad Sulthan Rasyid Rifai ◽  
Chusnul Choliq ◽  
Chairun Nisa ◽  
Danny Umbu Tay Hambandima

Seekor trenggiling jawa (<em>Manis javanica</em>) jantan berusia lima tahun menderita diare kronis selama dua bulan. Pemeriksaan hematologi dilakukan secara manual untuk mengetahui kondisi fisiologis trenggiling dengan parameter <em>Red Blood Cell </em>(RBC), <em>White Blood Cell </em>(WBC), <em>Packed Cell Volume </em>(PCV), hemoglobin (Hb), indeks RBC, dan diferensial WBC. Trenggiling diidentifikasi mengalami polisitemia relatif, dehidrasi, anemia mikrositik-normokromik, indikasi hipoksia, dan neutrofilia. Kondisi ini disebabkan oleh diare kronis akibat infeksi multi kausa dengan didominasi oleh infeksi bakteri yang menyebabkan trenggiling mengalami malnutrisi dan stres secara fisik dan fisiologis.


1992 ◽  
Vol 40 (4) ◽  
pp. 355 ◽  
Author(s):  
PBS Spencer ◽  
R Speare

The haematology of a colony of wild allied rock-wallabies, Petrogale assimilis Ramsay, 1877, from north-western Queensland was studied for 20 months. Wallabies were repeatedly trapped at monthly intervals and 511 blood samples from 96 animals were examined, making this the most comprehensive study of the haematology of any macropod species. The morphology of the red blood cells and leucocytes was similar to those of other marsupials. Large and small lymphocytes were recognised. Binucleate lymphocytes were found in 7.2% of blood smears. Normal haematological values were within the published ranges for other marsupials. However, the average white blood cell count (mean +/- s.e.: 9.03 +/- 0.92 X 10(9) L-1) was close to the upper end of the range for macropods. The normal (mean +/- s.e.) red blood cell count (5.24 + 0.15 X 10(12) L-1), packed cell volume (0.4291 +/- 0.019 L L-1) and haemoglobin concentration (14.07 +/- 0.41 g dL-1) of male wallabies were higher than those of females (4.79 +/- 0.15 X 10(12) L-1, 0.3952 +/- 1.19 L L-1, and 12.95 +/- 0.41 g dL-1, respectively). No gender differences were detected in the white blood cell count (9.03 +/- 0.92 x 10(9) L-1), mean corpuscular volume (82.28 +/- 1.35 fL), mean corpuscular haemoglobin (26.98 +/- 0.57 pg) or mean corpuscular haemoglobin concentration (32.82 +/- 0.57 g L 1). The red blood cell count, packed cell volume, haemoglobin concentration, mean corpuscular haemoglobin, mean corpuscular haemoglobin concentration and the absolute neutrophil count in juveniles and subadults increased with age. The neutrophil to lymphocyte ratio was less than 1.0 in pouch young and approached 1.0 in adults. The red blood cell count, packed cell volume and haemoglobin concentration of lactating females did not vary with age of pounch young.


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