scholarly journals Shape Optimization of Thermoacoustic Systems Using a 2D Adjoint Helmholtz Solver

2020 ◽  
Author(s):  
Stefano Falco ◽  
Matthew Juniper
Keyword(s):  
Shape Optimization ◽  
Longitudinal Mode ◽  
Swirl Combustor ◽  
Rijke Tube ◽  
Thermoacoustic Instabilities ◽  
Iterative Design ◽  
The Mean ◽  
Strong Candidate ◽  
First Time ◽  
Shape Changes

Abstract Thermoacoustic instabilities, which arise due to the interaction between flames and acoustics, are sensitive to small changes to the system parameters. In this paper, we apply adjoint-based shape optimization to a 2D finite element Helmholtz solver to find accurately and inexpensively the shape changes that most stabilise a 2D thermoacoustic system in the linear regime. We examine two cases: a Rijke tube and a turbulent swirl combustor. Both systems exhibit an unstable longitudinal mode and we suppress the instability by slightly modifying the geometry. In the case of the turbulent swirl combustor, the sensitivities are higher in the plenum and in the burner than in the combustion chamber, mainly due to the effect of the mean temperature. In the cooler regions, the local wavelength is shorter, which means that geometry changes of a given distance have more influence than they do where the local wavelength is longer. This is the first time adjoint-based shape optimization is applied to 2D Helmholtz solvers in thermoacoustics, after being previously applied to low-order thermoacoustic networks. But Helmholtz solvers have an intrinsic advantage: they can handle complex geometries. The easy scalability of this method to complex 3D geometries make this tool a strong candidate for the iterative design of thermoacoustically stable combustors.

Shape Optimization of Thermoacoustic Systems Using a 2D Adjoint Helmholtz Solver

2020 ◽  
Author(s):  
Stefano Falco ◽  
Matthew P. Juniper
Keyword(s):  
Shape Optimization ◽  
Longitudinal Mode ◽  
Swirl Combustor ◽  
Rijke Tube ◽  
Thermoacoustic Instabilities ◽  
Iterative Design ◽  
The Mean ◽  
Strong Candidate ◽  
First Time ◽  
Shape Changes

Abstract Thermoacoustic instabilities, which arise due to the interaction between flames and acoustics, are sensitive to small changes to the system parameters. In this paper, we apply adjoint-based shape optimization to a 2D finite element Helmholtz solver to find accurately and inexpensively the shape changes that most stabilise a 2D thermoacoustic system in the linear regime. We examine two cases: a Rijke tube and a turbulent swirl combustor. Both systems exhibit an unstable longitudinal mode and we suppress the instability by slightly modifying the geometry. In the case of the turbulent swirl combustor, the sensitivities are higher in the plenum and in the burner than in the combustion chamber, mainly due to the effect of the mean temperature. In the cooler regions, the local wavelength is shorter, which means that geometry changes of a given distance have more influence than they do where the local wavelength is longer. This is the first time adjoint-based shape optimization is applied to 2D Helmholtz solvers in thermoacoustics, after being previously applied to low-order thermoacoustic networks. But Helmholtz solvers have an intrinsic advantage: they can handle complex geometries. The easy scalability of this method to complex 3D geometries make this tool a strong candidate for the iterative design of thermoacoustically stable combustors.

RESULTS OF INTRALESIONAL TRIAMCINOLONE ACETONIDE FOR CHALAZION TREATMENT

2011 ◽  
pp. 100-104
Author(s):  
Thi Thu Nguyen ◽  
Viet Hien Vo ◽  
Thi Em Do
Keyword(s):  
Success Rate ◽  
Key Words ◽  
Triamcinolone Acetonide ◽  
Lower Eyelid ◽  
Upper Eyelid ◽  
Interventional Trial ◽  
The Mean ◽  
First Time

The study use intralesional triamcinolone acetonide injection proceduce for chalazion treatment.1. Objectives: To evaluate results of intralesional triamcinolone acetonide injection for chalazion treatment. 2. Method: This noncomparative prospective interventional trial included 72 chalazions of 61 patients. 3. Results: 61 patients (72 chalazions) with 19 males (31.1%) và 42 females (68.9%), the mean age was 24 ± 9,78 years. 31.1% patients was the first time chalazion and 68.9% patients was more than one times chalazion including 78.6% patients was recurrent at the first position and 21.4% patients occur at new position. 72 chalazions with 16 (22.2%) chalazions was treated before and 56 (77.8%) chalazions wasn’t done that. 72 chalazions with 49 chalazions (68.1%) are local in upper eyelid and 23 chalazions (31.9%) are local in lower eyelid. The mean of chalazion diameter is 6.99 ± 3.03mm. Intralesional triamcinolone acetonide is injected to treat 72 chalazions with 16 (22.2%) chalazions are injected through the route of skin and 56 (77.8%) chalazions are injected through the route of conjunctiva. After 2 weeks follow-up, the success rate was 93.1% and 6.9% failed. 4. Conclusion: intralesional triamcinolone acetonide injection for chalazion treatment is really effective. Key words: chalazion, intralesional triamcinolone acetonide.

Synthesis of a silymarin-gold nanoparticle conjugate and analysis of its liver-protecting activity

2021 ◽  
Vol 22 ◽  
Author(s):  
Sergey Staroverov ◽  
Sergey Kozlov ◽  
Alexander Fomin ◽  
Konstantib Gabalov ◽  
Alexey Volkov ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Liver Disease ◽  
Carbon Tetrachloride ◽  
Glutathione Depletion ◽  
Laboratory Animals ◽  
Experimental Hepatitis ◽  
Acute Liver Disease ◽  
The Mean ◽  
Extent Of Damage ◽  
First Time

Background: The liver disease problem prompts investigators to search for new methods of liver treatment. Introduction: Silymarin (Sil) protects the liver by reducing the concentration of free radicals and the extent of damage to the cell membranes. A particularly interesting method to increase the bioavailability of Sil is to use synthesized gold nanoparticles (AuNPs) as reagents. The study considered whether it was possible to use the silymarin-AuNP conjugate as a potential liver-protecting drug. Method: AuNPs were conjugated to Sil and examine the liver-protecting activity of the conjugate. Experimental hepatitis and hepatocyte cytolysis after carbon tetrachloride actionwere used as a model system, and the experiments were conducted on laboratory animals. Result: For the first time, silymarin was conjugated to colloidal gold nanoparticles (AuNPs). Electron microscopy showed that the resultant preparations were monodisperse and that the mean conjugate diameter was 18–30 nm ± 0.5 nm (mean diameter of the native nanoparticles, 15 ± 0.5 nm). In experimental hepatitis in mice, conjugate administration interfered with glutathione depletion in hepatocytes in response to carbon tetrachloride was conducive to an increase in energy metabolism, and stimulated the monocyte–macrophage function of the liver. The results were confirmed by the high respiratory activity of the hepatocytes in cell culture. Conclusion: We conclude that the silymarin-AuNP conjugate holds promise as a liver-protecting agent in acute liver disease caused by carbon tetrachloride poisoning.

scholarly journals Neutrosophic ratio-type estimators for estimating the population mean

2021 ◽  
Author(s):  
Zaigham Tahir ◽  
Hina Khan ◽  
Muhammad Aslam ◽  
Javid Shabbir ◽  
Yasar Mahmood ◽  
...  
Keyword(s):  
Minimum Mean Square Error ◽  
Auxiliary Information ◽  
Population Parameter ◽  
Uncertain Information ◽  
Population Mean ◽  
Classical Statistics ◽  
Neutrosophic Statistics ◽  
The Mean ◽  
Type Data ◽  
First Time

AbstractAll researches, under classical statistics, are based on determinate, crisp data to estimate the mean of the population when auxiliary information is available. Such estimates often are biased. The goal is to find the best estimates for the unknown value of the population mean with minimum mean square error (MSE). The neutrosophic statistics, generalization of classical statistics tackles vague, indeterminate, uncertain information. Thus, for the first time under neutrosophic statistics, to overcome the issues of estimation of the population mean of neutrosophic data, we have developed the neutrosophic ratio-type estimators for estimating the mean of the finite population utilizing auxiliary information. The neutrosophic observation is of the form $${Z}_{N}={Z}_{L}+{Z}_{U}{I}_{N}\, {\rm where}\, {I}_{N}\in \left[{I}_{L}, {I}_{U}\right], {Z}_{N}\in [{Z}_{l}, {Z}_{u}]$$ Z N = Z L + Z U I N where I N ∈ I L , I U , Z N ∈ [ Z l , Z u ] . The proposed estimators are very helpful to compute results when dealing with ambiguous, vague, and neutrosophic-type data. The results of these estimators are not single-valued but provide an interval form in which our population parameter may have more chance to lie. It increases the efficiency of the estimators, since we have an estimated interval that contains the unknown value of the population mean provided a minimum MSE. The efficiency of the proposed neutrosophic ratio-type estimators is also discussed using neutrosophic data of temperature and also by using simulation. A comparison is also conducted to illustrate the usefulness of Neutrosophic Ratio-type estimators over the classical estimators.

scholarly journals P1398 Echocardiographic continuous monitoring of exercise stress test using probe fixation device

2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
K Wdowiak-Okrojek ◽  
P Wejner-Mik ◽  
Z Bednarkiewicz ◽  
P Lipiec ◽  
J D Kasprzak
Keyword(s):  
Image Quality ◽  
Physical Exercise ◽  
Stress Test ◽  
Exercise Stress Test ◽  
Bicycle Ergometer ◽  
Exercise Stress ◽  
Fixation Device ◽  
The Mean ◽  
First Time

Abstract Background Stress echocardiography (SE) plays an important role among methods of noninvasive diagnosis of ischemic disease. Despite the advantages of physical exercise as the most physiologic stressor, it is difficult (bicycle ergometer) or impossible (treadmill) to obtain and maintain the acoustic window during the exercise. Recently, an innovative probe fixation device was introduced and a research plan was developed to assess the feasibility of external probe fixation during exercise echocardiography on a supine bicycle and upright treadmill exercise for the first time. Methods 37 subjects (36 men, mean age 39 ± 16 years, 21 healthy volunteers, 16 patients with suspected coronary artery disease) were included in this study. This preliminary testing stage included mostly men due to more problematic probe fixation in women. All subjects underwent a submaximal exercise stress test on a treadmill (17/37) or bicycle ergometer (11/37). Both sector and matrix probes were used. We assessed semi-quantitatively the quality of acquired apical views at each stage – the four-point grading system was used (0-no view, 1-suboptimal quality, 2-optimal quality, 3-very good quality), 2-3 sufficient for diagnosis. Results The mean time required for careful positioning of the probe and image optimization was 12 ± 3 min and shortened from 13,7 to 11,1 minutes (mean) in first vs second half of the cohort documenting learning curve. At baseline, 9 patients had at least one apical view of quality precluding reliable analysis. Those patients were excluded from further assessment. During stress, 17 patients maintained the optimal or very good quality of all apical views, whereas in 11 patients the quality significantly decreased during the stress test and required probe repositioning. The mean image quality score at baseline was 2,61 ± 0,48 and 2,25 ± 0,6 after exercise. Expectedly, good image quality was easier to obtain and maintain in the supine position (score 2,74 ± 0,44) points as compared with upright position (score 2,25 ± 0,57). Conclusion This preliminary, unique experience with external probe fixation device indicates that continuous acquisition and monitoring of echocardiographic images is feasible during physical exercise, and for the first time ever - also on the treadmill. This feasibility data stem from almost exclusively male patients and the estimated rate of sufficient image quality throughout the entire test is currently around 60%. We are hoping, that gaining more experience with the product could increase the success rate on exercise tests. Abstract P1398 Figure. Treadmill and ergometer stress test

Étude du développement hétéroblastique chez quelques espèces du genre Medicago

1983 ◽  
Vol 61 (8) ◽  
pp. 2212-2223 ◽  
Author(s):  
Catherine Damerval
Keyword(s):  
Environmental Conditions ◽  
Mean Value ◽  
Annual Species ◽  
The Mean ◽  
Shape Changes

Seven foliar types were defined for the first leaf in the heteroblastic development of seven annual species of Medicago L. Among the species, M. aculeata and M. murex have a typical foliar form. There is no relation between the first leaf and the succeeding trifoliolate one. The shape changes of the middle foliole of the trifoliolate leaves during the development allowed to establish a foliar sequence whose mean length was used to suggest an evolutive hierarchy among the taxa. Five quantitative variables were analysed on the first and on the sixth leaf for stability according to environmental conditions; the two stable variables (L/l and L/Pl) have a best discriminant value for the first leaf than for the sixth one. However, intraspecific heterogeneity is high in both cases. A relation between the flowering precocity and the mean value of one of the sixth leaf's variables (that is, the ratio of the length to the width of the foliole limb) was demonstrated in four species only. The heteroblastic development not only allows to establish a relation between foliar stage and physiologic age, but it itself constitutes a very good taxonomic and systematic criterium; it allowed to identify the seven species studied.

THE INFLUENCE OF WEIGHT AND HEIGHT ON WEIGHT CHANGES ASSOCIATED WITH PREGNANCY IN WOMEN

1957 ◽  
Vol 15 (4) ◽  
pp. 423-429 ◽  
Author(s):  
THOMAS McKEOWN ◽  
R. G. RECORD
Keyword(s):  
Weight Change ◽  
Weight Changes ◽  
Body Build ◽  
Weight Increment ◽  
Time Table ◽  
The Mean ◽  
Significant Change ◽  
First Time

SUMMARY Three hundred and eighty-three women whose weights were recorded during and after pregnancy were divided into groups of short (under 64 in.) and tall (64 in. and over) individuals, and further subdivided according to an index of body build (based on the observed regression of antenatal weight on height). Differences between the weight 12 months after delivery and the antenatal weight (adjusted according to the number of days by which it preceded or followed the 124th day of gestation) were examined. The proportion of short women who added weight in this interval was relatively high for those who were thinnest at the antenatal examination, was lowest for those who were moderately thin and thereafter increased with increasing degree of obesity (from about 1 in 3 to 4 in 5); the proportion of tall women who added weight showed no significant change (Fig. 2). This variation in weight change according to height is exhibited by women pregnant for the first time (Table 3). For both short and tall women, the mean weight increment of those who added weight, and the mean weight decrement of those who lost weight, increased with increasing degree of obesity (Fig. 3). When weight change is expressed as a proportion of the antenatal weight these trends disappear (Fig. 4).

scholarly journals Modeling of temporal groundwater level variations based on a Kalman filter adaptation algorithm with exogenous inputs

2016 ◽  
Vol 19 (2) ◽  
pp. 191-206 ◽  
Author(s):  
Emmanouil A. Varouchakis
Keyword(s):  
Kalman Filter ◽  
Groundwater Level ◽  
Auxiliary Information ◽  
Model Parameters ◽  
Adaptation Algorithm ◽  
Arx Model ◽  
Resources Management ◽  
Temporal Modelling ◽  
The Mean ◽  
First Time

Reliable temporal modelling of groundwater level is significant for efficient water resources management in hydrological basins and for the prevention of possible desertification effects. In this work we propose a stochastic method of temporal monitoring and prediction that can incorporate auxiliary information. More specifically, we model the temporal (mean annual and biannual) variation of groundwater level by means of a discrete time autoregressive exogenous variable (ARX) model. The ARX model parameters and its predictions are estimated by means of the Kalman filter adaptation algorithm (KFAA) which, to our knowledge, is applied for the first time in hydrology. KFAA is suitable for sparsely monitored basins that do not allow for an independent estimation of the ARX model parameters. We apply KFAA to time series of groundwater level values from the Mires basin in the island of Crete. In addition to precipitation measurements, we use pumping data as exogenous variables. We calibrate the ARX model based on the groundwater level for the years 1981 to 2006 and use it to predict the mean annual and biannual groundwater level for recent years (2007–2010). The predictions are validated with the available annual averages reported by the local authorities.

A review of radiation doses and associated parameters in western australian mining operations (2018-20)

2021 ◽  
Author(s):  
Martin Ian Ralph ◽  
Marcus Cattani
Keyword(s):  
Effective Dose ◽  
Annual Reports ◽  
Radiological Protection ◽  
Annual Dose ◽  
Mining Operations ◽  
Decay Series ◽  
Dose Coefficients ◽  
The Mean ◽  
Institutional Controls ◽  
First Time

Abstract In the 2019-20 reporting period, nineteen mining operations in Western Australia were identified as having workers who were likely to be exposed to ionising radiation stemming from naturally occurring radioactive materials (NORMs), seventeen of which, known hereinafter as Reporting Entities (REs), were required to submit an annual report of the dose estimates of their workforce to the mining regulatory authority. In 2018 the International Commission for Radiological Protection published the revision of the Dose Coefficients (DCs) for occupational intakes of radionuclides of the uranium-238 and thorium-232 decay series, in ICRP-137 and ICRP-141. The 2019-20 annual reports are the first to apply the revised DCs to estimate worker doses. The mean effective dose (ED) reported by the 17 REs increased by 32.4% to 0.94 mSv in 2019-20 from 0.71 mSv reported in 2018-19, indicating that the mean ED is approaching the 1 mSv annual dose estimate at which regulatory intervention should be considered. The mean committed effective dose (CED) from inhalation of dusts containing long-lived alpha-emitting (LLα) nuclides has increased by 35% from 0.40 mSv in 2018-19 to 0.54 mSv in 2019-20. The maximum CED from LLα increased by 16.3% from 3.20 mSv in 2018-19 to 3.72 mSv in 2019-20. The authors consider that, in the absence of other explanations provided by the REs, the increase is largely attributable to the revised DC’s published in ICRP-137 and ICRP-141, but highlight that there are significant variations between REs that make a generalised conclusion problematic. The maximum reported ED in 2019-20 was 6.0 mSv, an increase of 36.4% from 2018-19 (4.4 mSv). The 2019-20 reporting period is the first time in a decade in which mine worker EDs have been elevated to the point that EDs have exceeded 5 mSv, a level at which personal monitoring and additional institutional controls are required.

Analytical approach unifying the two-regime scaling for bedload particle motions

2021 ◽  
Author(s):  
Zi Wu ◽  
Arvind Singh ◽  
Efi Foufoula-Georgiou ◽  
Michele Guala ◽  
Xudong Fu ◽  
...  
Keyword(s):  
Travel Time ◽  
Velocity Variation ◽  
Travel Times ◽  
Scaling Exponents ◽  
Time Scaling ◽  
Dispersion Regime ◽  
The Mean ◽  
Bedload Sediment ◽  
Distance Travel ◽  
First Time

<p>Bedload particle hops are defined as successive motions of a particle from start to stop, characterizing one of the most fundamental processes describing bedload sediment transport in rivers. Although two transport regimes have been recently identified for short- and long-hops, respectively <strong>(Wu et al., <em>Water Resour Res</em>, 2020)</strong>, there still lacks a theory explaining how the mean hop distance-travel time scaling may extend to cover the phenomenology of bedload particle motions. Here we propose a velocity-variation based formulation, and for the first time, we obtain analytical solution for the mean hop distance-travel time relation valid for the entire range of travel times, which agrees well with the measured data <strong>(Wu et al., <em>J Fluid Mech</em>, 2021)</strong>. Regarding travel times, we identify three distinct regimes in terms of different scaling exponents: respectively as ~1.5 for an initial regime and ~5/3 for a transition regime, which define the short-hops; and 1 for the so-called Taylor dispersion regime defining long-hops. The corresponding probability density function of the hop distance is also analytically obtained and experimentally verified. </p>

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