THE INFLUENCE OF WEIGHT AND HEIGHT ON WEIGHT CHANGES ASSOCIATED WITH PREGNANCY IN WOMEN

1957 ◽  
Vol 15 (4) ◽  
pp. 423-429 ◽  
Author(s):  
THOMAS McKEOWN ◽  
R. G. RECORD

SUMMARY Three hundred and eighty-three women whose weights were recorded during and after pregnancy were divided into groups of short (under 64 in.) and tall (64 in. and over) individuals, and further subdivided according to an index of body build (based on the observed regression of antenatal weight on height). Differences between the weight 12 months after delivery and the antenatal weight (adjusted according to the number of days by which it preceded or followed the 124th day of gestation) were examined. The proportion of short women who added weight in this interval was relatively high for those who were thinnest at the antenatal examination, was lowest for those who were moderately thin and thereafter increased with increasing degree of obesity (from about 1 in 3 to 4 in 5); the proportion of tall women who added weight showed no significant change (Fig. 2). This variation in weight change according to height is exhibited by women pregnant for the first time (Table 3). For both short and tall women, the mean weight increment of those who added weight, and the mean weight decrement of those who lost weight, increased with increasing degree of obesity (Fig. 3). When weight change is expressed as a proportion of the antenatal weight these trends disappear (Fig. 4).

2010 ◽  
Vol 105 (7) ◽  
pp. 1047-1054 ◽  
Author(s):  
Zumin Shi ◽  
Baojun Yuan ◽  
Gang Hu ◽  
Yue Dai ◽  
Hui Zuo ◽  
...  

The aim of the present study was to examine the association between dietary patterns and weight change prospectively. We followed up 1231 adults aged 20 years and older (mean age 49·3 years) from 2002 to 2007. Food intake was assessed at baseline by an FFQ. Factor analysis was used to identify dietary patterns. Nutrient intake was measured by food weighing plus consecutive individual 3 d food records. Body weight and height were measured. The mean 5-year weight gain among all participants was 0·8 (sd4·7) kg. The mean weight changes across quartiles of the ‘traditional’ pattern (rice, fresh vegetables, pork and wheat flour) were 2·0, 0·6, 0·6 and 0·0 kg. The corresponding values were 0·4, 0·5, 0·7 and 1·6 kg across quartiles of the ‘vegetable-rich’ pattern. No significant association between the ‘macho’ dietary pattern (meat and alcohol), the ‘sweet tooth’ pattern (drinks and cake) and weight gain was found. In multivariate linear regression, using the first quartile as the reference, participants in the highest quartile of the ‘traditional’ pattern had a β of − 2·18 (95 % CI − 2·91, − 1·45) for weight gain. However, the β from weight change of the highest quartile of the ‘vegetable-rich’ pattern was 1·00 (95 % CI 0·25, 1·74). In conclusion, the ‘traditional’ dietary pattern was negatively and the ‘vegetable-rich’ pattern was positively associated with weight gain in Chinese adults.


2011 ◽  
pp. 100-104
Author(s):  
Thi Thu Nguyen ◽  
Viet Hien Vo ◽  
Thi Em Do

The study use intralesional triamcinolone acetonide injection proceduce for chalazion treatment.1. Objectives: To evaluate results of intralesional triamcinolone acetonide injection for chalazion treatment. 2. Method: This noncomparative prospective interventional trial included 72 chalazions of 61 patients. 3. Results: 61 patients (72 chalazions) with 19 males (31.1%) và 42 females (68.9%), the mean age was 24 ± 9,78 years. 31.1% patients was the first time chalazion and 68.9% patients was more than one times chalazion including 78.6% patients was recurrent at the first position and 21.4% patients occur at new position. 72 chalazions with 16 (22.2%) chalazions was treated before and 56 (77.8%) chalazions wasn’t done that. 72 chalazions with 49 chalazions (68.1%) are local in upper eyelid and 23 chalazions (31.9%) are local in lower eyelid. The mean of chalazion diameter is 6.99 ± 3.03mm. Intralesional triamcinolone acetonide is injected to treat 72 chalazions with 16 (22.2%) chalazions are injected through the route of skin and 56 (77.8%) chalazions are injected through the route of conjunctiva. After 2 weeks follow-up, the success rate was 93.1% and 6.9% failed. 4. Conclusion: intralesional triamcinolone acetonide injection for chalazion treatment is really effective. Key words: chalazion, intralesional triamcinolone acetonide.


Author(s):  
Sergey Staroverov ◽  
Sergey Kozlov ◽  
Alexander Fomin ◽  
Konstantib Gabalov ◽  
Alexey Volkov ◽  
...  

Background: The liver disease problem prompts investigators to search for new methods of liver treatment. Introduction: Silymarin (Sil) protects the liver by reducing the concentration of free radicals and the extent of damage to the cell membranes. A particularly interesting method to increase the bioavailability of Sil is to use synthesized gold nanoparticles (AuNPs) as reagents. The study considered whether it was possible to use the silymarin-AuNP conjugate as a potential liver-protecting drug. Method: AuNPs were conjugated to Sil and examine the liver-protecting activity of the conjugate. Experimental hepatitis and hepatocyte cytolysis after carbon tetrachloride actionwere used as a model system, and the experiments were conducted on laboratory animals. Result: For the first time, silymarin was conjugated to colloidal gold nanoparticles (AuNPs). Electron microscopy showed that the resultant preparations were monodisperse and that the mean conjugate diameter was 18–30 nm ± 0.5 nm (mean diameter of the native nanoparticles, 15 ± 0.5 nm). In experimental hepatitis in mice, conjugate administration interfered with glutathione depletion in hepatocytes in response to carbon tetrachloride was conducive to an increase in energy metabolism, and stimulated the monocyte–macrophage function of the liver. The results were confirmed by the high respiratory activity of the hepatocytes in cell culture. Conclusion: We conclude that the silymarin-AuNP conjugate holds promise as a liver-protecting agent in acute liver disease caused by carbon tetrachloride poisoning.


Author(s):  
Zaigham Tahir ◽  
Hina Khan ◽  
Muhammad Aslam ◽  
Javid Shabbir ◽  
Yasar Mahmood ◽  
...  

AbstractAll researches, under classical statistics, are based on determinate, crisp data to estimate the mean of the population when auxiliary information is available. Such estimates often are biased. The goal is to find the best estimates for the unknown value of the population mean with minimum mean square error (MSE). The neutrosophic statistics, generalization of classical statistics tackles vague, indeterminate, uncertain information. Thus, for the first time under neutrosophic statistics, to overcome the issues of estimation of the population mean of neutrosophic data, we have developed the neutrosophic ratio-type estimators for estimating the mean of the finite population utilizing auxiliary information. The neutrosophic observation is of the form $${Z}_{N}={Z}_{L}+{Z}_{U}{I}_{N}\, {\rm where}\, {I}_{N}\in \left[{I}_{L}, {I}_{U}\right], {Z}_{N}\in [{Z}_{l}, {Z}_{u}]$$ Z N = Z L + Z U I N where I N ∈ I L , I U , Z N ∈ [ Z l , Z u ] . The proposed estimators are very helpful to compute results when dealing with ambiguous, vague, and neutrosophic-type data. The results of these estimators are not single-valued but provide an interval form in which our population parameter may have more chance to lie. It increases the efficiency of the estimators, since we have an estimated interval that contains the unknown value of the population mean provided a minimum MSE. The efficiency of the proposed neutrosophic ratio-type estimators is also discussed using neutrosophic data of temperature and also by using simulation. A comparison is also conducted to illustrate the usefulness of Neutrosophic Ratio-type estimators over the classical estimators.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Clare Shakespeare ◽  
Handsome Dube ◽  
Sikhangezile Moyo ◽  
Solwayo Ngwenya

Abstract Background On the 27th of March 2020 the Zimbabwean government declared the Covid-19 pandemic a ‘national disaster’. Travel restrictions and emergency regulations have had significant impacts on maternity services, including resource stock-outs, and closure of antenatal clinics during the lockdown period. Estimates of the indirect impact of Covid-19 on maternal and perinatal mortality was expected it to be considerable, but little data was yet available. This study aimed to examine the impact of Covid-19 and lockdown control measures on non-Covid outcomes in a government tertiary level maternity unit in Bulawayo, Zimbabwe, by comparing maternal and perinatal morbidity and mortality before, and after the lockdown was implemented. Methods This was a retrospective, observational study, using a cross-sectional design to compare routine monthly maternal and perinatal statistics three months before and after Covid-19 emergency measures were implemented at Mpilo Central Hospital. Results Between January-March and April-June 2020, the mean monthly deliveries reduced from 747.3 (SD ± 61.3) in the first quarter of 2020 to 681.0 (SD ± 17.6) during lockdown, but this was not statistically significant, p = 0.20. The Caesarean section rates fell from a mean of 29.8% (SD ± 1.7) versus 28.0% (SD ± 1.7), which was also not statistically significant, p = 0.18. During lockdown, the percentage of women delivering at Mpilo Central Hospital who were booked at the hospital fell from a mean of 41.6% (SD ± 1.1) to 35.8% (SD ± 4.3) which was statistically significant, p = 0.03. There was no significant change, however, in maternal mortality or severe maternal morbidity (such as post-partum haemorrhage (PPH), uterine rupture, and severe preeclampsia/eclampsia), stillbirth rate or special care baby unit admission. There was an increase in the mean total number of early neonatal deaths (ENND) (mean 18.7 (SD ± 2.9) versus 24.0 (SD ± 4.6), but this was not statistically significant, p = 0.32. Conclusions Overall, maternity services at Mpilo showed resilience during the lockdown period, with no significant change in maternal and perinatal adverse outcomes, with the same number of man-hours worked before and during the lockdown Maternal and perinatal outcomes should continue to be monitored to assess the impact of Covid-19 and the lockdown measures as the pandemic in Zimbabwe unfolds. Further studies would be beneficial to explore women’s experiences and understand how bookings and deliveries at local clinics changed during this time.


2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
K Wdowiak-Okrojek ◽  
P Wejner-Mik ◽  
Z Bednarkiewicz ◽  
P Lipiec ◽  
J D Kasprzak

Abstract Background Stress echocardiography (SE) plays an important role among methods of noninvasive diagnosis of ischemic disease. Despite the advantages of physical exercise as the most physiologic stressor, it is difficult (bicycle ergometer) or impossible (treadmill) to obtain and maintain the acoustic window during the exercise. Recently, an innovative probe fixation device was introduced and a research plan was developed to assess the feasibility of external probe fixation during exercise echocardiography on a supine bicycle and upright treadmill exercise for the first time. Methods 37 subjects (36 men, mean age 39 ± 16 years, 21 healthy volunteers, 16 patients with suspected coronary artery disease) were included in this study. This preliminary testing stage included mostly men due to more problematic probe fixation in women. All subjects underwent a submaximal exercise stress test on a treadmill (17/37) or bicycle ergometer (11/37). Both sector and matrix probes were used. We assessed semi-quantitatively the quality of acquired apical views at each stage – the four-point grading system was used (0-no view, 1-suboptimal quality, 2-optimal quality, 3-very good quality), 2-3 sufficient for diagnosis. Results The mean time required for careful positioning of the probe and image optimization was 12 ± 3 min and shortened from 13,7 to 11,1 minutes (mean) in first vs second half of the cohort documenting learning curve. At baseline, 9 patients had at least one apical view of quality precluding reliable analysis. Those patients were excluded from further assessment. During stress, 17 patients maintained the optimal or very good quality of all apical views, whereas in 11 patients the quality significantly decreased during the stress test and required probe repositioning. The mean image quality score at baseline was 2,61 ± 0,48 and 2,25 ± 0,6 after exercise. Expectedly, good image quality was easier to obtain and maintain in the supine position (score 2,74 ± 0,44) points as compared with upright position (score 2,25 ± 0,57). Conclusion This preliminary, unique experience with external probe fixation device indicates that continuous acquisition and monitoring of echocardiographic images is feasible during physical exercise, and for the first time ever - also on the treadmill. This feasibility data stem from almost exclusively male patients and the estimated rate of sufficient image quality throughout the entire test is currently around 60%. We are hoping, that gaining more experience with the product could increase the success rate on exercise tests. Abstract P1398 Figure. Treadmill and ergometer stress test


1970 ◽  
Vol 48 (4) ◽  
pp. 485-496 ◽  
Author(s):  
J. F. SMITH ◽  
T. J. ROBINSON

SUMMARY The levels of free oestrogen (oestrone and oestradiol-17β) in plasma in the ovarian vein were determined in three groups, each of 27 ewes, at nine intervals at about the time of oestrus. One group had a normal oestrus while the other two had been treated for 16 days with intravaginal sponges containing either 10 or 30 mg of a synthetic progestagen (Cronolone, Searle). In untreated ewes, the mean level (corrected) of oestradiol-17β in plasma from the active ovary rose from 25·3 ng/100 ml at −48 h to a peak of 91·6 ng/100 ml at 0 h (onset of oestrus) and then fell. There was evidence of biphasic production. The mean level of oestrone was relatively high (13·0 ng/100 ml) at −48 h; it fell to 2·0 ng/100 ml between −36 and −24 h and then rose again to 9·4 ng/100 ml at + 12 h. There was no significant change, with time, in the plasma levels of either oestrogen from the non-active ovary. The total amounts of oestradiol-17β and of oestrone produced from both ovaries at an oestrous period were estimated to average 9·7 and 2·4 μg. In treated ewes, a similar pattern of production of oestradiol-17β was shown by the ewes treated with 30 mg Cronolone. That of ewes treated with 10 mg differed (P < 0·01). Peak level was reached at an earlier stage, relative to the onset of oestrus, and it declined more rapidly, the total amount of oestrogen produced (oestrone + oestradiol-17β) was less (10 mg Cronolone, 8·6 μg; 30 mg Cronolone, 12·1 μg; normal oestrus, 12·1 μg), and there was no biphasic production.


2016 ◽  
Vol 19 (2) ◽  
pp. 191-206 ◽  
Author(s):  
Emmanouil A. Varouchakis

Reliable temporal modelling of groundwater level is significant for efficient water resources management in hydrological basins and for the prevention of possible desertification effects. In this work we propose a stochastic method of temporal monitoring and prediction that can incorporate auxiliary information. More specifically, we model the temporal (mean annual and biannual) variation of groundwater level by means of a discrete time autoregressive exogenous variable (ARX) model. The ARX model parameters and its predictions are estimated by means of the Kalman filter adaptation algorithm (KFAA) which, to our knowledge, is applied for the first time in hydrology. KFAA is suitable for sparsely monitored basins that do not allow for an independent estimation of the ARX model parameters. We apply KFAA to time series of groundwater level values from the Mires basin in the island of Crete. In addition to precipitation measurements, we use pumping data as exogenous variables. We calibrate the ARX model based on the groundwater level for the years 1981 to 2006 and use it to predict the mean annual and biannual groundwater level for recent years (2007–2010). The predictions are validated with the available annual averages reported by the local authorities.


Author(s):  
Martin Ian Ralph ◽  
Marcus Cattani

Abstract In the 2019-20 reporting period, nineteen mining operations in Western Australia were identified as having workers who were likely to be exposed to ionising radiation stemming from naturally occurring radioactive materials (NORMs), seventeen of which, known hereinafter as Reporting Entities (REs), were required to submit an annual report of the dose estimates of their workforce to the mining regulatory authority. In 2018 the International Commission for Radiological Protection published the revision of the Dose Coefficients (DCs) for occupational intakes of radionuclides of the uranium-238 and thorium-232 decay series, in ICRP-137 and ICRP-141. The 2019-20 annual reports are the first to apply the revised DCs to estimate worker doses. The mean effective dose (ED) reported by the 17 REs increased by 32.4% to 0.94 mSv in 2019-20 from 0.71 mSv reported in 2018-19, indicating that the mean ED is approaching the 1 mSv annual dose estimate at which regulatory intervention should be considered. The mean committed effective dose (CED) from inhalation of dusts containing long-lived alpha-emitting (LLα) nuclides has increased by 35% from 0.40 mSv in 2018-19 to 0.54 mSv in 2019-20. The maximum CED from LLα increased by 16.3% from 3.20 mSv in 2018-19 to 3.72 mSv in 2019-20. The authors consider that, in the absence of other explanations provided by the REs, the increase is largely attributable to the revised DC’s published in ICRP-137 and ICRP-141, but highlight that there are significant variations between REs that make a generalised conclusion problematic. The maximum reported ED in 2019-20 was 6.0 mSv, an increase of 36.4% from 2018-19 (4.4 mSv). The 2019-20 reporting period is the first time in a decade in which mine worker EDs have been elevated to the point that EDs have exceeded 5 mSv, a level at which personal monitoring and additional institutional controls are required.


2021 ◽  
Author(s):  
Zi Wu ◽  
Arvind Singh ◽  
Efi Foufoula-Georgiou ◽  
Michele Guala ◽  
Xudong Fu ◽  
...  

&lt;p&gt;Bedload particle hops are defined as successive motions of a particle from start to stop, characterizing one of the most fundamental processes describing bedload sediment transport in rivers. Although two transport regimes have been recently identified for short- and long-hops, respectively &lt;strong&gt;(Wu et al., &lt;em&gt;Water Resour Res&lt;/em&gt;, 2020)&lt;/strong&gt;, there still lacks a theory explaining how the mean hop distance-travel time scaling may extend to cover the phenomenology of bedload particle motions. Here we propose a velocity-variation based formulation, and for the first time, we obtain analytical solution for the mean hop distance-travel time relation valid for the entire range of travel times, which agrees well with the measured data &lt;strong&gt;(Wu et al., &lt;em&gt;J Fluid Mech&lt;/em&gt;, 2021)&lt;/strong&gt;. Regarding travel times, we identify three distinct regimes in terms of different scaling exponents: respectively as ~1.5 for an initial regime and ~5/3 for a transition regime, which define the short-hops; and 1 for the so-called Taylor dispersion regime defining long-hops. The corresponding probability density function of the hop distance is also analytically obtained and experimentally verified.&amp;#160;&lt;/p&gt;


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