Design Elements Inflatable Origami-Based Forceps

2020 ◽  
Author(s):  
Dina Joy K. Abulon ◽  
J. Michael McCarthy
Keyword(s):  
Shape Transformation ◽  
Design Elements ◽  
Stiffness Adjustment ◽  
Selection Of ◽  
Inflatable Structure

Abstract Forceps are a multifunctional tool that can solve various grasping needs. An action origami-based forcep design allows a structure to deploy from a flat state to 3D state plus create motion while in a final 3D state. The origami-based design allows the structure to compact. A fabric inflatable structure allows for shape transformation and stiffness adjustment. This paper explores the design of three prototypes and guides the selection of optimal features of inflatable action origami-based forceps.

scholarly journals Chimeric Fusion (F) and Attachment (G) Glycoprotein Antigen Delivery by mRNA as a Candidate Nipah Vaccine

2021 ◽  
Vol 12 ◽  
Author(s):  
Rebecca J. Loomis ◽  
Anthony T. DiPiazza ◽  
Samantha Falcone ◽  
Tracy J. Ruckwardt ◽  
Kaitlyn M. Morabito ◽  
...  
Keyword(s):  
Nipah Virus ◽  
Neutralizing Antibody ◽  
T Cell Response ◽  
Antigen Delivery ◽  
Design Elements ◽  
C Terminus ◽  
Glycoprotein Antigen ◽  
Pandemic Threat ◽  
Covalently Linked ◽  
Selection Of

Nipah virus (NiV) represents a significant pandemic threat with zoonotic transmission from bats-to-humans with almost annual regional outbreaks characterized by documented human-to-human transmission and high fatality rates. Currently, no vaccine against NiV has been approved. Structure-based design and protein engineering principles were applied to stabilize the fusion (F) protein in its prefusion trimeric conformation (pre-F) to improve expression and increase immunogenicity. We covalently linked the stabilized pre-F through trimerization domains at the C-terminus to three attachment protein (G) monomers, forming a chimeric design. These studies detailed here focus on mRNA delivery of NiV immunogens in mice, assessment of mRNA immunogen-specific design elements and their effects on humoral and cellular immunogenicity. The pre-F/G chimera elicited a strong neutralizing antibody response and a superior NiV-specific Tfh and other effector T cell response compared to G alone across both the mRNA and protein platforms. These findings enabled final candidate selection of pre-F/G Fd for clinical development.

All Is Right with the World

2015 ◽  
Vol 6 (4) ◽  
pp. 78-94
Author(s):  
Sharath Sasidharan
Keyword(s):  
Cognitive Dissonance ◽  
Important Determinant ◽  
Belief Systems ◽  
Consumer Trust ◽  
Website Design ◽  
Design Elements ◽  
Schema Congruity ◽  
Business To Consumer ◽  
The Impact ◽  
Selection Of

Business-to-Consumer e-commerce vendors view consumer trust as an important determinant of purchasing intent. Based on the cognitive dissonance and schema-congruity theories, this paper examines the impact of schema-congruity between the website design elements of color and typography with the product context in impacting trust. Websites perceived as compatible with subconsciously internalized belief systems and hence deemed schema-congruent by consumers are expected to engender higher levels of trust. A controlled experimental study involving 128 participants spanning eight different schema-congruency conditions was conducted. Results indicated that completely schema-congruent websites engendered higher levels of trust. Partially schema-congruent and schema-incongruent websites registered significantly lower levels of trust due to cognitive dissonance arising out of their incompatibility with consumer belief systems. The judicious selection of color and typography perceived as schema-congruent with the product context can serve to enhance consumer trust in e-commerce websites.

scholarly journals The association of typography with form and content in digital games

2016 ◽  
Author(s):  
Seza Soyluçiçek
Keyword(s):  
User Interface ◽  
Interface Design ◽  
Game Design ◽  
Digital Games ◽  
Concept Design ◽  
Environment Design ◽  
Design Elements ◽  
Printed Media ◽  
Correct Usage ◽  
Selection Of

The aim of this study is to define the correct usage of the connection between the typographic elements in digital games and the form and content of game concept. In this work, the points to take into consideration while utilizing this connection correctly and the effective usage of typographic elements with game graphics will be scrutinized. Along with the character, object and environment design that is composed of the story and concept design which underlies the game design, the selection of the typeface in games is also one of the points to be considered. The typographic elements are substantial design elements of a game design along with the character, environment and level design. The typographic elements of a game are helpful to enable the connection between the user and the game and to direct the user in the game. In this sense, from the game's opening scene, the selection of typefaces that are used in logos, menus, and directions increases in importance. Moreover, in both visual and technical manners the usage of typography in games brings different approaches compared to the ones used in the printed media. To illuminate these topics, successful game examples will be analyzed. The selection of typefaces used in the examples will be looked at from the point of subject, concept and audience and the principles of the correct usage of typography will be mentioned. Along with these, the rareness of the resources about the usage of typography in game design raises the importance of this work.Keywords: Game design, typography, type face, user interface design.

Exploring the design elements of open evaluation

2017 ◽  
Vol 10 (1) ◽  
pp. 40-65 ◽  
Author(s):  
Jörg B.A. Haller ◽  
Vivek K. Velamuri ◽  
Dirk Schneckenberg ◽  
Kathrin M. Möslein
Keyword(s):  
Design Methodology ◽  
Research Approach ◽  
Content Type ◽  
Design Elements ◽  
Wide Range ◽  
External Stakeholders ◽  
Innovation Contest ◽  
Innovation Processes ◽  
Practical Implications ◽  
Selection Of

Purpose Firms increasingly integrate a wide range of actors in the early ideation and concept creation phases of innovation processes leading to the collection of a large number of ideas. This creates the challenge of filtering the most promising ideas from a large number of submissions. The use of external stakeholders into the evaluation and selection of submissions (i.e. open evaluation (OE)) might be a viable alternative. The purpose of this paper is to provide a state-of-the-art analysis on how such OE systems are designed and structured. Design/methodology/approach Since OE is a new phenomenon, an exploratory qualitative research approach is adopted. In all, 122 instances of OE in 90 innovation contest cases are examined for their design elements. Findings This research reveals that OE systems are configured in many different ways. In total, 32 design elements and their respective parameters are identified and described along the six socio-technical system components of an OE system. This study allows for a comprehensive understanding of what OE is and what factors need to be taken into consideration when designing an OE system. Practical implications Scholars and professionals may draw insights on what design choices to make when implementing OE. Originality/value The comprehensive analysis performed in this study contributes to research on open and user innovation by examining the concept of OE. In particular, it extends knowledge on design elements of OE systems.

Illumination design patterns for homogenization and color mixing

2019 ◽  
Vol 8 (1) ◽  
pp. 13-32
Author(s):  
Julius Muschaweck ◽  
Henning Rehn
Keyword(s):  
Design Pattern ◽  
Design Patterns ◽  
Optical Design ◽  
Color Variation ◽  
Light Sources ◽  
Illumination Design ◽  
Design Elements ◽  
White Leds ◽  
Color Mixing ◽  
Selection Of

Abstract In illumination optics, color mixing is a key design task, but the realization can be a challenge. While tunable light sources based on multiple LEDs are commonplace, color homogenization is just as important for white LEDs, due to their spatial and angular color variation. In this tutorial, we first look at color mixing from an abstract, phase space-based viewpoint. From there, we derive a taxonomy of color mixing problems: How is the multi-color light source composed? What kind of homogeneity is required in the target? How is the homogenization influenced by source and target étendue? We categorize these problems and we present a toolbox: A selection of optical design elements, e.g. mixing rods and fly’s eye arrays, and we show for each design pattern how it fits into the taxonomy.

Selection of Product Design Configuration for Improved Sustainability Using the Product Sustainability Index (ProdSI) Scoring Method

2013 ◽  
Vol 315 ◽  
pp. 51-56 ◽  
Author(s):  
Mohd Fahrul Hassan ◽  
Muhamad Zameri Mat Saman ◽  
Safian Sharif ◽  
Badrul Omar ◽  
X. Zhang ◽  
...  
Keyword(s):  
Product Design ◽  
Sustainable Product Design ◽  
Scoring Method ◽  
New Approach ◽  
Design Elements ◽  
Sustainability Index ◽  
Sustainability Performance ◽  
Sustainable Product ◽  
Selection Of

Generating new variants for design elements of products, structuring them into a complete configuration and evaluating the alternate configurations are essential for product design. Evaluating the likely product configurations in terms of sustainability aspects continues to become a useful aspect of interest to product designers. This paper proposes a new approach for applying the Product Sustainability Index (ProdSI) in selecting the best possible configurations for product design. In this paper, the recently developed ProdSI methodology is used to evaluate sustainability performance of a product. The approach is useful for product designers to generate numerous likely product design configurations and subsequently select the most sustainable product design configuration. An example of an armed-chair is used to illustrate the proposed new approach.

scholarly journals Exploitation of AM-Potentials by Linking Manufacturing Processes to Function-Driven Product Design

2019 ◽  
Vol 1 (1) ◽  
pp. 739-748
Author(s):  
Jannik Reichwein ◽  
Jerome Kaspar ◽  
Michael Vielhaber ◽  
Eckhard Kirchner
Keyword(s):  
Design Guidelines ◽  
Design Elements ◽  
The Past ◽  
Component Design ◽  
Technological Growth ◽  
Manufactured Products ◽  
Innovative Products ◽  
Am Processes ◽  
Selection Of

AbstractAdditive Manufacturing (AM) processes had an extensively and substantially technological growth over the past years that directly influences the continuously increased and manifold possibilities for processing new and innovative products. However, additively manufactured products mostly are still fabricated with only small adaptions compared to conventional parts, and thus waste many design potentials although specific design guidelines have been widely developed to restrict geometrical deficiencies or suggest improvements in component design.As a result, this contribution furtherly aims to systematically consider AM potentials already on the functional level of product development offering significant but until now still not or just insufficiently exploited potentials. Therefore, the presented approach uses the already proven Design Pattern Matrix (DPM) approach for conventional technologies extended by a concurrent selection of materials and processes specifically for AM. Here, the DPM derives information about the manufacturing process in form of design elements and links them to the function carriers of the product including a methodological determination of requirements.

scholarly journals Design and Numerical Study of the Novel Manifold Header for the Evacuated Tube Solar Collector

Energies ◽  
2020 ◽  
Vol 13 (10) ◽  
pp. 2450
Author(s):  
Martin Beer ◽  
Radim Rybár ◽  
Michal Cehlár ◽  
Sergey Zhironkin ◽  
Peter Sivák
Keyword(s):  
Numerical Study ◽  
Cfd Analysis ◽  
The Novel ◽  
Design Elements ◽  
Serial Connection ◽  
Final Design ◽  
Computational Fluid Dynamics Cfd ◽  
Evacuated Tube ◽  
Prototype Phase ◽  
Selection Of

The presented paper dealt with the concept of an innovative manifold header for evacuated tube solar collectors. The proposed concept eliminates the drawbacks of conventional manifold headers, especially the serial connection of heat pipes that operate under uneven conditions. The advantage of the proposed design of the manifold header is also an increase in the heat exchange surface and the possibility of conducting the heat transfer media flow in a parallel flow arrangement, which increases the overall efficiency. The concept of the manifold header was evaluated on five variations of design with the use of the computational fluid dynamics (CFD) analysis. The results of the CFD analysis confirmed the functionality of the concept and also enabled the selection of the most suitable design elements, which were incorporated into the final design of a manifold header in the pre-prototype phase of manufacturing.

scholarly journals Design and Redesign of a Multimodal Classroom Task – Implications for Teaching and Learning

10.28945/2127 ◽  
2015 ◽  
Vol 14 ◽  
pp. 139-159 ◽  
Author(s):  
Anne Öman ◽  
Sylvana Sofkova Hashemi
Keyword(s):  
Teaching And Learning ◽  
School Level ◽  
Learning Trajectory ◽  
Digital Resources ◽  
Design Elements ◽  
Central Mode ◽  
Primary Focus ◽  
Introductory Classes ◽  
Selection Of

Digital technologies are increasingly implemented in Swedish schools, which impact on education in the contemporary classroom. Screen-based practice opens up for new forms and multiplicity of representations, taking into account that language in a globalized society is more than reading and writing skills. This paper presents a case study of technology-mediated instruction at the primary-school level including an analysis of the designed task and how the teacher orchestrated the digital resources during three introductory classes. The aim was also to explore the pupils’ redesigning of advertising films based on teacher’s instructions and available digital resources. Sequences of a learning trajectory were video recorded and analysed from a multimodal perspective with a focus on the designed task and the processes of how pupils orchestrate meaning through their selection and configuration of available designs. The findings show a distinction between the selection of design elements in the teacher’s orchestration of the laptop resources during instruction and the pupils’ redesigning of the task. Pupils’ work developed from the linguistic design provided by the teacher towards visual design and the use of images as the central mode of expression in the process of creating advertising films. The findings also indicate a lack of orientation towards subject content due to the teacher’s primary focus on introducing the software.

Cognitive gadgets and cognitive priors

2019 ◽  
Vol 42 ◽  
Author(s):  
Gian Domenico Iannetti ◽  
Giorgio Vallortigara
Keyword(s):  
Cognitive Neuroscience ◽  
Selection Of

Abstract Some of the foundations of Heyes’ radical reasoning seem to be based on a fractional selection of available evidence. Using an ethological perspective, we argue against Heyes’ rapid dismissal of innate cognitive instincts. Heyes’ use of fMRI studies of literacy to claim that culture assembles pieces of mental technology seems an example of incorrect reverse inferences and overlap theories pervasive in cognitive neuroscience.

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