A Parametric Study on Material Properties of Cortical Shell and Trabecular Core in an Osteoporotic, Lumbar Vertebral Bone Model
This study is about understanding the biomechanical parameters in osteoporosis phenomena. Experimental data are available on intact cadaver normal and osteoporotic lumbar vertebrae. It was observed that there is inconsistency between the clinical DEXA measurements and the mechanical measurements such as failure strength. The vertebral bone parameters include geometry (height, width, curvature, and thickness of the cortical shell) and material properties of cortical and trabecular bone. A non-linear Micromodel Finite Element Analysis (MFEA) program has been developed to include these parameters and obtain the compressive load. Response surface methodology (RSM) was developed to relate BMD to failure strength and is used in this study to see how the mechanical properties of bone influence the failure load. (Sindall, 2003)