scholarly journals Molecular Epidemiology of Staphylococcus spp. Contamination in the Ward Environment: Study on mecA and femA Genes in Methicillin-Resistant Strains

1995 ◽  
Vol 69 (1) ◽  
pp. 15-20
Author(s):  
Atsushi ASHIMOTO ◽  
Takeshi HAMADA ◽  
Akiko ADACHI ◽  
Takahiko TANIGAWA ◽  
Yoshinori TANAKA
Keyword(s):  
Molecular Epidemiology ◽  
Methicillin Resistant ◽  
Environment Study ◽  
Resistant Strains ◽  
Staphylococcus Spp

Multidrug resistant coagulase-negative Staphylococcus spp. isolated from cases of chronic rhinosinusitis in humans. Study from Poland

2021 ◽  
Keyword(s):  
Chronic Rhinosinusitis ◽  
Pathogenic Bacteria ◽  
Medical Center ◽  
Multidrug Resistant ◽  
Coagulase Negative Staphylococcus ◽  
Coagulase Negative Staphylococci ◽  
Methicillin Resistant ◽  
Resistant Strains ◽  
Ethmoid Sinuses ◽  
Staphylococcus Spp

Abstract For many years, coagulase-negative staphylococci (CoNS) have been considered non-pathogenic bacteria. However, recently, CoNS are becoming more common bacteriological factors isolated from cases of chronic rhinosinusitis in humans. Moreover, most of them represent the multidrug-resistant or/and methicillin-resistant profile, which significantly increases the therapeutic difficulties. The aim of the study was to characterize profile of resistant coagulase-negative staphylococci isolated from cases of chronic rhinosinusitis in patients treated in a Medical Center in Warsaw in 2015–2016. The study material was derived from patients with diagnosed chronic rhinosinusitis treated at the MML Medical Center in Warsaw. The material was obtained intraoperatively from maxillary, frontal, and ethmoid sinuses. In total, 1,044 strains were isolated from the studied material. Coagulase-negative staphylococci were predominant, with the largest share of Staphylococcus epidermidis. Isolated CoNS were mainly resistant to macrolide, lincosamide, and tetracycline. Among the S. epidermidis strains, we also showed 35.6% of MDR and 34.7% of methicillin-resistant strains. The same values for other non-epidermidis species were 31.5% and 18.5%, respectively and the percentage of strains with MAR >0.2 was greater in S. epidermidis (32.6%) than S. non-epidermidis (23.9%). Although the percentage of strains resistant to tigecycline, glycopeptides, rifampicin and oxazolidinones was very small (2.3%, 1.9%, 1.4% and 0.7% respectively), single strains were reported in both groups. The study has shown a high proportion of MDR and methicillin-resistant CoNS strains, which indicates a large share of drug-resistant microorganisms in the process of persistence of chronic rhinosinusitis; therefore, isolation of this group of microorganisms from clinical cases using aseptic techniques should not be neglected.

scholarly journals Methicillin-resistant Staphylococcus spp. isolated from curd cheese “requeijão” and “especialidade láctea type requeijão” sold in Brazil

2017 ◽  
Vol 47 (7) ◽  
Author(s):  
Jamile de Oliveira Hachiya ◽  
Gabriel Augusto Marques Rossi ◽  
Laryssa Freitas Ribeiro ◽  
Rafael Akira Sato ◽  
Higor Oliveira Silva ◽  
...  
Keyword(s):  
Dairy Products ◽  
Meca Gene ◽  
Multidrug Resistant ◽  
Human Medicine ◽  
Methicillin Resistant ◽  
Heat Treated ◽  
Antimicrobial Resistance Profile ◽  
Resistance To Penicillin ◽  
Resistant Strains ◽  
Staphylococcus Spp

ABSTRACT: This study focused on counting Staphylococcus spp. in curd cheeses “requeijão” and “especialidade láctea type requeijão” sold in Brazil, assessing the presence of mecA gene in obtained isolates and establishing antimicrobial resistance profile of the mecA gene positive isolates. To this, a set of 200 samples of these dairy products were evaluated. Low counts of Staphylococcus spp. were observed in these dairy products. All the isolates were determined as coagulase-negative strains using coagulase test and PCR. However, two isolates (3.70%) were carriers of mecA gene and they can be considered as risk for public health. These isolates presented resistance to penicillin, oxacillin and erythromycin. In conclusion, low counts of Staphylococcus were detected in curd cheese “requeijão” and “especialidade láctea type requeijão” sold in Brazil. However, coagulase-negative methicillin-resistant Staphylococcus spp. was detected in these dairy products. This is the first report of the detection of methicillin-resistant Staphylococcus spp. in heat-treated dairy products in Brazil. Results served as a warning to public sanitary authorities to control multidrug-resistant strains in veterinary and human medicine.

scholarly journals Update on major clones of methicillin-resistant Staphylococcus aureus colonizing and/or infecting humans and its distribution in Brazil

2017 ◽  
Vol 7 (19) ◽  
pp. 93
Author(s):  
Thaina Miranda Da Costa ◽  
Valéria Vieira ◽  
Fábio Aguiar Alves
Keyword(s):  
Staphylococcus Aureus ◽  
Molecular Epidemiology ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Therapeutic Option ◽  
Antibiotics Resistance ◽  
Healthy Individuals ◽  
Antimicrobial Drugs ◽  
Methicillin Resistant ◽  
Resistant Strains ◽  
Low Prevalence

Staphylococcus aureus is a bacterium well known for its ability to acquire genes for resistance to antimicrobial drugs. A few years after the discovery of penicillin, which initiated the era of antibiotics, resistance to this drug had already been reported in hospitals and in a few decades also became a problem within the communities. Likewise, shortly after the introduction of methicillin as a therapeutic option, the resistance was observed. The indiscriminate use of antibiotics is an important factor contributing to the emergence of new resistant strains. This pathogen has the ability to spread rapidly and asymptomatically among healthy individuals. Infections caused by Methicillin-Resistant Staphylococcus aureus (MRSA) have reached a global share and are increasing in hospitals and community, including countries that previously had a low prevalence of MRSA history, exposing a significant diversity of clones identified. Outbreaks of infections caused by strains of Community-Associated Methicillin-Resistant Staphylococcus aureus (CA-MRSA) have been reported worldwide, including Brazil, where there is currently an epidemic of CA-MRSA. The present article intends to review the molecular epidemiology of methicillin-resistant Staphylococcus aureus and its evolution, with a focus on the clones distributed in Brazil.

scholarly journals Update on major clones of methicillin-resistant Staphylococcus aureus colonizing and/or infecting humans and its distribution in Brazil

2017 ◽  
Vol 7 (19) ◽  
pp. 93-105
Author(s):  
Thaina Miranda Da Costa ◽  
Valéria Vieira ◽  
Fábio Aguiar Alves
Keyword(s):  
Staphylococcus Aureus ◽  
Molecular Epidemiology ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Therapeutic Option ◽  
Antibiotics Resistance ◽  
Healthy Individuals ◽  
Antimicrobial Drugs ◽  
Methicillin Resistant ◽  
Resistant Strains ◽  
Low Prevalence

Staphylococcus aureus is a bacterium well known for its ability to acquire genes for resistance to antimicrobial drugs. A few years after the discovery of penicillin, which initiated the era of antibiotics, resistance to this drug had already been reported in hospitals and in a few decades also became a problem within the communities. Likewise, shortly after the introduction of methicillin as a therapeutic option, the resistance was observed. The indiscriminate use of antibiotics is an important factor contributing to the emergence of new resistant strains. This pathogen has the ability to spread rapidly and asymptomatically among healthy individuals. Infections caused by Methicillin-Resistant Staphylococcus aureus (MRSA) have reached a global share and are increasing in hospitals and community, including countries that previously had a low prevalence of MRSA history, exposing a significant diversity of clones identified. Outbreaks of infections caused by strains of Community-Associated Methicillin-Resistant Staphylococcus aureus (CA-MRSA) have been reported worldwide, including Brazil, where there is currently an epidemic of CA-MRSA. The present article intends to review the molecular epidemiology of methicillin-resistant Staphylococcus aureus and its evolution, with a focus on the clones distributed in Brazil.

scholarly journals Antibiotic Resistance Profile and Biofilm Production of Staphylococcus pseudintermedius Isolated from Dogs in Thailand

2021 ◽  
Vol 14 (6) ◽  
pp. 592
Author(s):  
Pavarish Jantorn ◽  
Hawaree Heemmamad ◽  
Tanawan Soimala ◽  
Saowakon Indoung ◽  
Jongkon Saising ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Meca Gene ◽  
Staphylococcus Pseudintermedius ◽  
Methicillin Resistant ◽  
Antibiotic Resistance Profile ◽  
Biofilm Production ◽  
Southern Thailand ◽  
Life Threatening ◽  
Suitable Treatment ◽  
Resistant Strains

Staphylococcus pseudintermedius is a zoonotic pathogen that can cause life-threatening infections in animals and humans. The study of methicillin-resistant S. pseudintermedius (MRSP) and its ability to produce biofilms is important to select the most suitable treatment. The prevalence and characteristics of S. pseudintermedius isolated from dogs admitted at the Veterinary Teaching Hospital, Prince of Songkla University, Thailand were assessed. Results showed that 28.30% (15/53) of the isolates were MRSP. Amplification of the mecA gene was observed in 93.33% (14/15) MRSP. Methicillin-resistant strains revealed co-resistant patterns against other antibiotics, including chloramphenicol, clindamycin, tetracycline, clarithromycin, ciprofloxacin, and trimethoprim. In this study, all bacterial isolates produced biofilms, while 90.55% of S. pseudintermedius isolates were strong or moderate biofilm producers. Most (45–60%) of the resistant strains were strong biofilm producers, while the correlation between biofilm production and antibiotic resistance was not statistically significant. This is the first study in southern Thailand to investigate the drug-resistant profile of S. pseudintermedius and its ability to form biofilm. The results will contribute to a better understanding of the emergence and prevalence of antimicrobial resistance in S. pseudintermedius.

scholarly journals Pefloxacin therapy for experimental endocarditis caused by methicillin-susceptible or methicillin-resistant strains of Staphylococcus aureus.

1985 ◽  
Vol 27 (5) ◽  
pp. 685-687 ◽  
Author(s):  
P M Sullam ◽  
M G Tauber ◽  
C J Hackbarth ◽  
H F Chambers ◽  
K G Scott ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Methicillin Resistant ◽  
Resistant Strains

scholarly journals Ceftaroline Activity against Bacterial Pathogens Frequently Isolated in U.S. Medical Centers: Results from Five Years of the AWARE Surveillance Program

2015 ◽  
Vol 59 (4) ◽  
pp. 2458-2461 ◽  
Author(s):  
Helio S. Sader ◽  
Robert K. Flamm ◽  
Jennifer M. Streit ◽  
David J. Farrell ◽  
Ronald N. Jones
Keyword(s):  
Staphylococcus Aureus ◽  
Streptococcus Pneumoniae ◽  
Bacterial Pathogens ◽  
Surveillance Program ◽  
Broth Microdilution ◽  
Methicillin Resistant ◽  
Content Type ◽  
Medical Centers ◽  
Resistant Strains

ABSTRACTA total of 84,704 isolates were collected from 191 medical centers in 2009 to 2013 and tested for susceptibility to ceftaroline and comparator agents by broth microdilution methods. Ceftaroline inhibited allStaphylococcus aureusisolates at ≤2 μg/ml and was very active against methicillin-resistant strains (MIC at which 90% of the isolates tested are inhibited [MIC90], 1 μg/ml; 97.6% susceptible). AmongStreptococcus pneumoniaeisolates, the highest ceftaroline MIC was 0.5 μg/ml, and ceftaroline activity against the most commonEnterobacteriaceaespecies (MIC50, 0.12 μg/ml; 78.9% susceptible) was similar to that of ceftriaxone (MIC50, ≤0.25 μg/ml; 86.8% susceptible).

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