Pharmacological Targeting of the Integrated Protein Kinase B, Phosphatase and Tensin Homolog Deleted on Chromosome 10, and Transforming Growth Factor-β Pathways in Prostate Cancer

Protein Kinase B ◽

Chromosome 10 ◽

Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) and PH domain and leucine-rich repeat phosphatase cross-talk (PHLPP) in cancer cells and in transforming growth factor β-activated stem cells.

Journal of Biological Chemistry ◽

10.1074/jbc.a113.537241 ◽

2017 ◽

Vol 292 (2) ◽

pp. 760-760

Author(s):

Aram Ghalali ◽

Zhi-wei Ye ◽

Johan Högberg ◽

Ulla Stenius

Keyword(s):

Stem Cells ◽

Growth Factor ◽

Cancer Cells ◽

Leucine Rich Repeat ◽

Ph Domain ◽

Chromosome 10 ◽

Phosphatase and Tensin Homolog Deleted on Chromosome 10 (PTEN) and PH Domain and Leucine-rich Repeat Phosphatase Cross-talk (PHLPP) in Cancer Cells and in Transforming Growth Factor β-Activated Stem Cells

Journal of Biological Chemistry ◽

10.1074/jbc.m113.537241 ◽

2014 ◽

Vol 289 (17) ◽

pp. 11601-11615 ◽

Cited By ~ 9

Author(s):

Aram Ghalali ◽

Zhi-wei Ye ◽

Johan Högberg ◽

Ulla Stenius

Keyword(s):

Stem Cells ◽

Growth Factor ◽

Cancer Cells ◽

Leucine Rich Repeat ◽

Ph Domain ◽

Chromosome 10 ◽

Transforming Growth Factor β-regulated MicroRNA-29a Promotes Angiogenesis through Targeting the Phosphatase and Tensin Homolog in Endothelium

Journal of Biological Chemistry ◽

10.1074/jbc.m112.444463 ◽

2013 ◽

Vol 288 (15) ◽

pp. 10418-10426 ◽

Cited By ~ 43

Author(s):

Jun Wang ◽

Youliang Wang ◽

Yu Wang ◽

Ying Ma ◽

Yu Lan ◽

...

Keyword(s):

Growth Factor ◽

Phosphoinositide 3-kinase (PI3K); phosphatase and tensin homolog deleted on chromosome 10 (PTEN; MMAC1; TEP1); protein kinase B (PKB; PKBA; AKT; AKT1)

Science-Business eXchange ◽

10.1038/scibx.2013.578 ◽

2013 ◽

Vol 6 (23) ◽

pp. 578-578

Keyword(s):

Protein Kinase ◽

Protein Kinase B ◽

Chromosome 10 ◽

Tensin Homolog ◽

Phosphoinositide 3 Kinase

Type III Transforming Growth Factor-β Receptor Drives Cardiac Hypertrophy Through β-Arrestin2–Dependent Activation of Calmodulin-Dependent Protein Kinase II

Hypertension ◽

10.1161/hypertensionaha.116.07420 ◽

2016 ◽

Vol 68 (3) ◽

pp. 654-666 ◽

Cited By ~ 9

Author(s):

Jie Lou ◽

Dan Zhao ◽

Ling-Ling Zhang ◽

Shu-Ying Song ◽

Yan-Chao Li ◽

...

Keyword(s):

Growth Factor ◽

Protein Kinase ◽

Cardiac Hypertrophy ◽

Dependent Protein Kinase ◽

Type Iii ◽

Protein Kinase Ii ◽

Dependent Protein ◽

Β Receptor

Genistein Inhibits Matrix Metalloproteinase Type 2 Activation and Prostate Cancer Cell Invasion by Blocking the Transforming Growth Factor β-Mediated Activation of Mitogen-Activated Protein Kinase-Activated Protein Kinase 2-27-kDa Heat Shock Protein Pathway

Molecular Pharmacology ◽

10.1124/mol.106.023861 ◽

2006 ◽

Vol 70 (3) ◽

pp. 869-877 ◽

Cited By ~ 53

Author(s):

Li Xu ◽

Raymond C. Bergan

Keyword(s):

Prostate Cancer ◽

Protein Kinase ◽

Cell Invasion ◽

Prostate Cancer Cell ◽

Mitogen Activated Protein Kinase ◽

Cancer Cell Invasion ◽

Mitogen Activated Protein

Differential effects of transforming growth factor β on human prostate cancer cells in vitro

Molecular and Cellular Endocrinology ◽

10.1016/0303-7207(89)90115-9 ◽

1989 ◽

Vol 62 (1) ◽

pp. 79-87 ◽

Cited By ~ 111

Author(s):

George Wilding ◽

Gerhard Zugmeier ◽

Cornelius Knabbe ◽

Katherine Flanders ◽

Edward Gelmann

Keyword(s):

Prostate Cancer ◽

Growth Factor ◽

Cancer Cells ◽

Human Prostate ◽

Human Prostate Cancer ◽

Prostate Cancer Cells ◽

Differential Effects

Osthole protects against inflammation in a rat model of chronic kidney failure via suppression of nuclear factor-κB, transforming growth factor-β1 and activation of phosphoinositide 3-kinase/protein kinase B/nuclear factor (erythroid-derived 2)-like 2 signaling

Molecular Medicine Reports ◽

10.3892/mmr.2017.7125 ◽

2017 ◽

Vol 16 (4) ◽

pp. 4915-4921 ◽

Cited By ~ 6

Author(s):

Tao Huang ◽

Zhen Dong

Keyword(s):

Growth Factor ◽

Protein Kinase ◽

Rat Model ◽

Protein Kinase B ◽

Chronic Kidney Failure ◽

Nuclear Factor Κb ◽

Transforming Growth Factor Β1 ◽

Nuclear Factor ◽

Phosphoinositide 3 Kinase

Expression of human collagenase‐3 (MMP‐13) by fetal skin fibroblasts is induced by transforming growth factor‐β via p38 mitogen‐activated protein kinase

The FASEB Journal ◽

10.1096/fsb2fj000588fje ◽

2000 ◽

Vol 15 (6) ◽

pp. 1098-1100

Author(s):

Laura Ravanti ◽

Mervi Toriseva ◽

Risto Penttinen ◽

Timothy Crombleholme ◽

Marco Foschi ◽

...

Keyword(s):

Growth Factor ◽

Protein Kinase ◽

Skin Fibroblasts ◽

Mitogen Activated Protein Kinase ◽

Fetal Skin ◽

Mitogen Activated Protein

Editorial Comment from Dr Murtola to Reduction of prostate cancer incidence by naftopidil, an α1-adrenoceptor antagonist and transforming growth factor-β signaling inhibitor

International Journal of Urology ◽

10.1111/iju.12175 ◽

2013 ◽

Vol 20 (12) ◽

pp. 1227-1228

Author(s):

Teemu J Murtola

Keyword(s):

Prostate Cancer ◽

Growth Factor ◽

Editorial Comment ◽

Cancer Incidence ◽

Prostate Cancer Incidence ◽

Adrenoceptor Antagonist