Resveratrol Protects Mitochondria against Oxidative Stress through AMP-Activated Protein Kinase-Mediated Glycogen Synthase Kinase-3β Inhibition Downstream of Poly(ADP-ribose)polymerase-LKB1 Pathway

2009 ◽  
Vol 76 (4) ◽  
pp. 884-895 ◽  
Author(s):  
Sang Mi Shin ◽  
Il Je Cho ◽  
Sang Geon Kim
Keyword(s):  
Oxidative Stress ◽  
Protein Kinase ◽  
Glycogen Synthase ◽  
Glycogen Synthase Kinase ◽  
Glycogen Synthase Kinase 3Β ◽  
Amp Activated Protein Kinase

scholarly journals Knockdown of GSK3β increases basal autophagy and AMPK signalling in nutrient-laden human aortic endothelial cells

2016 ◽  
Vol 36 (5) ◽  
Author(s):  
Karen A. Weikel ◽  
José M. Cacicedo ◽  
Neil B. Ruderman ◽  
Yasuo Ido
Keyword(s):  
Endothelial Cells ◽  
Protein Kinase ◽  
Blood Vessels ◽  
Glycogen Synthase ◽  
Cellular Material ◽  
Glycogen Synthase Kinase ◽  
Glycogen Synthase Kinase 3Β ◽  
Aortic Endothelial Cells ◽  
Amp Activated Protein Kinase ◽  
Human Aortic Endothelial Cells

Suppression of the enzyme glycogen synthase kinase 3β (GSK3β) increases both the turnover of damaged cellular material and the activity of the enzyme AMP-activated protein kinase (AMPK) to potentially attenuate the damage inflicted by excess sugar and fat on blood vessels.

scholarly journals AMP-Activated Protein Kinase and Glycogen Synthase Kinase 3β Modulate the Severity of Sepsis-induced Lung injury

2015 ◽  
Vol 21 (1) ◽  
pp. 937-950 ◽  
Author(s):  
Zhongyu Liu ◽  
Nathaniel Bone ◽  
Shaoning Jiang ◽  
Dae Won Park ◽  
Jean-Marc Tadie ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Lung Injury ◽  
Glycogen Synthase ◽  
Glycogen Synthase Kinase ◽  
Glycogen Synthase Kinase 3Β ◽  
Amp Activated Protein Kinase
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