Coexistence ofmcr-1andblaNDM-1in Escherichia coli from Venezuela
2016 ◽
Vol 60
(10)
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pp. 6356-6358
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ABSTRACTWe studied the presence of the mobile colistin resistance genemcr-1in human, animal, and environmentalEnterobacteriaceaesamples from Cumana, Venezuela, that were collected in 2015. Themcr-1gene was detected in 2/93Escherichia coliisolates from swine (novel ST452) and human (ST19) samples that were resistant to colistin. Whole-genome sequencing and transformation experiments identifiedmcr-1on an IncI2 plasmid. One of the isolates also bore the widely spread carbapenemase NDM-1. A One Health approach is necessary to further elucidate the flux of these high-risk genes.
Keyword(s):
Keyword(s):
2016 ◽
Vol 60
(3)
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pp. 1935-1938
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2015 ◽
Vol 53
(11)
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pp. 3530-3538
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