An Immunocompromised Child with Bloodstream Infection Caused by Two Escherichia coli Strains, One Harboring NDM-5 and the Other Harboring OXA-48-Like Carbapenemase
2016 ◽
Vol 60
(6)
◽
pp. 3270-3275
◽
Keyword(s):
We describe a 16-year-old neutropenic patient from the Middle East with bloodstream infection caused by two carbapenemase-producingEscherichia coliisolates that we characterized by whole-genome sequencing. While one displayed meropenem resistance and wasblaNDMpositive, the other demonstrated meropenem susceptibility yet harboredblaOXA181(which encodes ablaOXA48-like enzyme). This report highlights the challenge of laboratory detection ofblaOXA48-like enzymes and the clinical implications of genotypic resistance detection in carbapenemase-producingEnterobacteriaceae.
2016 ◽
Vol 60
(3)
◽
pp. 1935-1938
◽
2016 ◽
Vol 60
(11)
◽
pp. 6962-6964
◽
Keyword(s):