scholarly journals Secretory immunoglobulin A response to Shiga toxin in rabbits: kinetics of the initial mucosal immune response and inhibition of toxicity in vitro and in vivo.

1989 ◽  
Vol 57 (7) ◽  
pp. 1885-1889 ◽  
Author(s):  
D F Keren ◽  
J E Brown ◽  
R A McDonald ◽  
J S Wassef
Keyword(s):  
Immune Response ◽  
Shiga Toxin ◽  
Immunoglobulin A ◽  
Mucosal Immune Response ◽  
Secretory Immunoglobulin A ◽  
Kinetics Of ◽  
Toxicity In Vitro ◽  
Secretory Immunoglobulin

scholarly journals Immunodiagnostics, immunotherapy and immunoprophylaxis in otorhinolaryngological practice. Report 3. Diagnostic approaches to the palatine tonsils functional state assessment for selecting a treatment strategy for patients with chronic tonsillitis (analytical summary)

2021 ◽  
pp. 22-31
Author(s):  
Oleg F. Melnikov ◽  
Dmitry I. Zabolotny ◽  
Alexander Yu. Bredun ◽  
Vasyl V. Kishchuk
Keyword(s):  
Immune Response ◽  
Stress Test ◽  
Immunoglobulin A ◽  
Low Frequency ◽  
Chronic Tonsillitis ◽  
Secretory Immunoglobulin A ◽  
Tonsil Tissue ◽  
Tonsillar Cells ◽  
Secretory Immunoglobulin

Experimental work carried out over the past 20 years to study the activity of various functional groups in tonsillar cells in patients with chronic tonsillitis (CT) under local exposure to various immune response modifiers showed that: - tonsillar cells from CT patients in 69.5% of cases are capable of increasing their immunofunctional activity under the influence of immune modifiers in vitro reactions; - the most active of the group of immunotropic immune response modifiers are T-activin and Thymogen; - it can be considered the optimal diagnostic technique to carry out a "stress" test on the tonsil tissue using nonspecific (alternating magnetic field of industrial (low) frequency and low-frequency ultrasound) and specific — a microbial vaccine when applied to the tonsil tissue; - a non-invasive method for recording changes in the tonsils after stimulation may be fluctuations in the level of secretory immunoglobulin A and α-interferon in saliva after the test; - an increase in the level of secretory immunoglobulin A and α-interferon by more than 1/3 of the initial level after the test is a clinically favorable sign and a recommendation for medical treatment to the managing of patients with CT.

A comparative study of secretory immunoglobulin A and immunoglobulin G in host defense in an in vitro pneumonia model

2006 ◽  
Vol 191 (3) ◽  
pp. 386-390 ◽  
Author(s):  
Lawrence N. Diebel ◽  
David M. Liberati ◽  
Michael T. White ◽  
Clement A. Diglio ◽  
William J. Brown
Keyword(s):  
Comparative Study ◽  
Host Defense ◽  
Immunoglobulin G ◽  
Immunoglobulin A ◽  
Secretory Immunoglobulin A ◽  
Secretory Immunoglobulin

Interaction of secretory immunoglobulin A antibodies withNaegleria fowleritrophozoites and collagen type I

2003 ◽  
Vol 49 (3) ◽  
pp. 164-170 ◽  
Author(s):  
Mineko Shibayama ◽  
José de Jesús Serrano-Luna ◽  
Saúl Rojas-Hernández ◽  
Rafael Campos-Rodríguez ◽  
Víctor Tsutsumi
Keyword(s):  
Collagen Type ◽  
Immunoglobulin A ◽  
Collagen Type I ◽  
Secretory Iga ◽  
Type I ◽  
Secretory Immunoglobulin A ◽  
Naegleria Fowleri ◽  
Nægleria Fowleri ◽  
Secretory Immunoglobulin

In this work, we analyzed the in vitro interaction of human secretory immunoglobulin A (sIgA) antibodies with Naegleria fowleri trophozoites and the capacity of these antibodies to inhibit amoeba adherence to collagen type I. We also studied N. fowleri antigens that are recognized by sIgA, using immunoblot assays. Immunocytochemical analysis of the interaction showed a redistribution of antigens on the surface of trophozoites by sIgA antibodies. Ultrastructural analysis of antibody–amoeba interaction showed that besides the patching and cap formation, parasites were capable of eliminating the antigen–antibody complex produced on the surface. sIgA antibodies were capable of inhibiting the in vitro adhesion of trophozoites to collagen type I. We suggest that nonsymptomatic infections by N. fowleri may stimulate a local specific immunity that prevents trophozoite adhesion and invasion of nasal mucosa.Key words: Naegleria fowleri, free-living amoebae, human antibodies, secretory IgA, mucosal immunity.

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