Isolation and Characterization of thenikR Gene Encoding a Nickel-Responsive Regulator inEscherichia coli
1999 ◽
Vol 181
(2)
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pp. 670-674
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Keyword(s):
ABSTRACT Expression of the nickel-specific transport system encoded by theEscherichia coli nikABCDE operon is repressed by a high concentration of nickel. By using random transposon Tn10 insertion, we isolated mutants in which expression of the nik operon became constitutive with respect to nickel. We have identified the corresponding nikR gene which encodes a nickel-responsive regulator. Expression of nikRwas partially controlled by Fnr through transcription from thenikA promoter region. In addition, a specific transcription start site for the constitutive expression of nikR was found 51 bp upstream of the nikR gene.
2001 ◽
Vol 3
(5)
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pp. 485-494
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Keyword(s):
1991 ◽
Vol 266
(26)
◽
pp. 17382-17387
1994 ◽
Vol 269
(17)
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pp. 12947-12953
2019 ◽
Vol 8
(2)
◽
pp. 43-48
1994 ◽
Vol 205
(2)
◽
pp. 1250-1256
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