scholarly journals The Atlas of Bacterial & Archaeal Cell Structure : an Interactive Open-Access Microbiology Textbook

2021 ◽  
Author(s):  
Catherine M. Oikonomou ◽  
Grant J. Jensen
Keyword(s):  
Open Access ◽  
Cell Structure ◽  
Digital Textbook ◽  
Link Type ◽  
Complex Functions

Here, we describe a new open-access digital textbook for microbiology, The Atlas of Bacterial & Archaeal Cell Structure (available at cellstructureatlas.org ). The book addresses a fundamental gap in existing textbooks, namely, what bacterial and archaeal cells look like and how the macromolecular structures they contain give rise to their diverse and complex functions.

scholarly journals The NALCN Channel Regulator UNC-80 Functions in a Subset of Interneurons To Regulate Caenorhabditis elegans Reversal Behavior

2019 ◽  
Vol 10 (1) ◽  
pp. 199-210 ◽  
Author(s):  
Chuanman Zhou ◽  
Jintao Luo ◽  
Xiaohui He ◽  
Qian Zhou ◽  
Yunxia He ◽  
...  
Keyword(s):  
Plant Hormone ◽  
Neuronal Excitability ◽  
Resting Membrane Potential ◽  
Loss Of Function ◽  
Wild Type ◽  
C Elegans ◽  
Link Type ◽  
Complex Functions ◽  
And Function ◽  
Multiple Loss

NALCN (Na+leak channel, non-selective) is a conserved, voltage-insensitive cation channel that regulates resting membrane potential and neuronal excitability. UNC79 and UNC80 are key regulators of the channel function. However, the behavioral effects of the channel complex are not entirely clear and the neurons in which the channel functions remain to be identified. In a forward genetic screen for C. elegans mutants with defective avoidance response to the plant hormone methyl salicylate (MeSa), we isolated multiple loss-of-function mutations in unc-80 and unc-79. C. elegans NALCN mutants exhibited similarly defective MeSa avoidance. Interestingly, NALCN, unc-80 and unc-79 mutants all showed wild type-like responses to other attractive or repelling odorants, suggesting that NALCN does not broadly affect odor detection or related forward and reversal behaviors. To understand in which neurons the channel functions, we determined the identities of a subset of unc-80-expressing neurons. We found that unc-79 and unc-80 are expressed and function in overlapping neurons, which verified previous assumptions. Neuron-specific transgene rescue and knockdown experiments suggest that the command interneurons AVA and AVE and the anterior guidepost neuron AVG can play a sufficient role in mediating unc-80 regulation of the MeSa avoidance. Though primarily based on genetic analyses, our results further imply that MeSa might activate NALCN by direct or indirect actions. Altogether, we provide an initial look into the key neurons in which the NALCN channel complex functions and identify a novel function of the channel in regulating C. elegans reversal behavior through command interneurons.

scholarly journals Erratum to: Voltage-gated Sodium Channels and Blockers: An Overview and Where Will They Go?

2020 ◽  
Author(s):  
Zhi-mei Li ◽  
Li-xia Chen ◽  
Hua Li
Keyword(s):  
Open Access ◽  
Sodium Channels ◽  
Voltage Gated ◽  
Internet Portal ◽  
Creative Commons ◽  
Link Type ◽  
Voltage Gated Sodium Channels

The article “Voltage-gated Sodium Channels and Blockers: An Overview and Where Will They Go?”, written by Zhi-mei LI, Li-xia CHEN, Hua LI, was originally published electronically on the publisher’s internet portal on December 2019 without open access. With the author(s)’ decision to opt for Open Choice, the copyright of the article is changed to © The Author(s) 2020 and the article is forthwith distributed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The original article has been corrected.Corresponding authors: Li-xia CHEN, Hua LI

scholarly journals Correction to: A review on the flow instability of nanofluids

2019 ◽  
Author(s):  
Jianzhong Lin ◽  
Hailin Yang
Keyword(s):  
Open Access ◽  
Flow Instability ◽  
Open Access Publication ◽  
Creative Commons ◽  
Link Type

The article [A review on the flow instability of nanofluids], written by [Jianzhong LIN, Hailin YANG], was originally published Online First without Open Access. After publication in volume [40], issue [9], page [1227-1238] the author decided to opt for Open Choice and to make the article an Open Access publication. Therefore, the copyright of the article has been changed to © The Author(s) [2019] and the article is forthwith distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits use, duplication, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

scholarly journals Erratum to: Anthropomorphism Indexes of the Kinematic Chain for Artificial Hands

2020 ◽  
Author(s):  
Immaculada Llop-Harillo ◽  
Antonio Pérez-González ◽  
Javier Andrés-Esperanza
Keyword(s):  
Open Access ◽  
Kinematic Chain ◽  
Internet Portal ◽  
Creative Commons ◽  
Link Type

The article “Anthropomorphism Indexes of the Kinematic Chain for Artificial Hands, written by Immaculada Llop-Harillo, Antonio Pérez-González, Javier Andrés-Esperanza, was originally published electronically on the publisher’s internet portal (currently SpringerLink) on May 23rd 2020 without open access. With the author(s)’ decision to opt for Open Choice the copyright of the article changed in October 2020 to © The Author(s) 2020 and the article is forthwith distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits use, duplication, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.The original article has been corrected.

scholarly journals SkewDB: A comprehensive database of GC and a 10 other skews for over 28,000 chromosomes and plasmids

2021 ◽  
Author(s):  
Bert Hubert
Keyword(s):  
Open Access ◽  
Codon Bias ◽  
Strand Bias ◽  
Equal Frequency ◽  
Link Type ◽  
Comprehensive Database ◽  
Parity Rule ◽  
Gc Skew ◽  
Open Access Database ◽  
Microbial Dna

ABSTRACTGC skew denotes the relative excess of G nucleotides over C nucleotides on the leading versus the lagging replication strand of eubacteria. While the effect is small, typically around 2.5%, it is robust and pervasive. GC skew and the analogous TA skew are a localized deviation from Chargaff’s second parity rule, which states that G and C, and T and A occur with (mostly) equal frequency even within a strand.Most bacteria also show the analogous TA skew. Different phyla show different kinds of skew and differing relations between TA and GC skew.This article introduces an open access database (https://skewdb.org) of GC and 10 other skews for over 28,000 chromosomes and plasmids. Further details like codon bias, strand bias, strand lengths and taxonomic data are also included. The SkewDB database can be used to generate or verify hypotheses. Since the origins of both the second parity rule, as well as GC skew itself, are not yet satisfactorily explained, such a database may enhance our understanding of microbial DNA.

scholarly journals Erratum zu: Wie verbindlich ist das Wissen vom Gene Editing? Ethische Reflexionen zu einem aktuellen Normierungsprozess

2019 ◽  
Vol 2 (2) ◽  
pp. 399-399
Author(s):  
Keyword(s):  
Open Access ◽  
Gene Editing ◽  
Link Type

Erratum zu:ZEMO 201910.1007/s42048-019-00043-6Der Artikel Wie verbindlich ist das Wissen vom Gene Editing? Ethische Reflexionen zu einem aktuellen Normierungsprozess von Stefanie Kiewitt-Straßburg wurde ursprünglich am 8. Oktober 2019 ohne „Open Access“ online auf der …

scholarly journals Correction to: Multi-fluid modelling of bubbly channel flows with an adaptive multi-group population balance method

2021 ◽  
Author(s):  
D. Papoulias ◽  
A. Vichansky ◽  
M. Tandon
Keyword(s):  
Open Access ◽  
Population Balance ◽  
Channel Flows ◽  
Balance Method ◽  
Open Access Publication ◽  
Internet Portal ◽  
Creative Commons ◽  
Link Type ◽  
Group Population

The article “Multi-fluid modelling of bubbly channel flows with an adaptive multi-group population balance method ” written by D. Papoulias, A. Vichansky, and M. Tandon, was originally published electronically on the publisher ’s internet portal (currently SpringerLink) on 21 October 2020 without open access. After publication in Volume 3, Issue 3, page 171–185, the author(s) decided to opt for Open Choice and to make the article an open access publication. Therefore, the copyright of the article has been changed to © The Author(s) 2021 and the article is forthwith distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits use, duplication, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

scholarly journals Clinical Case Reports: Why should health professionals care about them?

2015 ◽  
Keyword(s):  
Health Care ◽  
Open Access ◽  
Lifelong Learning ◽  
Health Care Professional ◽  
Clinical Case ◽  
Medical Literature ◽  
Case Reports ◽  
Diagnostic Methods ◽  
List Type ◽  
Link Type

I was born and raised in a medical family surrounded by physicians of various specialities and their friends. Although I dreamed of becoming a conductor of a symphony orchestra, my destiny was quite predetermined (genetically as well as epigenetically). So, I became a cardiologist. Right at the beginning of my career at the university hospital, I was told by senior physicians that to become a good medical professional you must read one clinical case report per day, at least. Indeed, it is not easy to see diverse patients every day and keep reading the medical literature. Eventually, I realized that following this rule I could easily come up with an initial diagnosis and selection of the right therapy for my patients. Clearly, clinical case reports remain an essential part of lifelong learning in medicine, contributing greatly to the progress of health care. That is why ScienceOpen aggregated extensive content from the medical literature published Open Access in the last 5-7 years and offers this invaluable material freely for every health care professional in the world. Another important aspect of continuing medical education involves the role of mentoring. Mentorship during the medical career can have an exceptional impact both professionally as well as personally. Supporting self-esteem and the importance of lifelong learning, a good mentor empowers a positive attitude and promotes the development of more open and flexible mindsets in medical trainees.  As a great example, I would like to mention a weekly clinical case reports discussion called clinical journal club presented by Professor Friedrich C. Luft, Director of the Experimental and Clinical Research Center (ECRC) at Charité and Max Delbrück Center in the Helmholtz Association in Berlin to his colleagues, physicians and researchers in a freely available open format: http://www.charite-buch.de/. During my own training as a physician-scientist, I met a few outstanding senior colleagues, unique leaders and incredible personalities such as Professor Mirsaid M. Mirrakhimov, Professor Rainer Dietz, Professor Detlev Ganten, and Professor Friedrich C. Luft. Now, Professor Friedrich C. Luft and I decided to initiate a special Open Access collection of clinical case reports across all medical disciplines. Friedrich Luft has expressed his thoughts and ideas on the Clinical Case Reports Collection in this short video:  https://youtu.be/XKKxxlPuUwM So, why should clinical case reports be published? Here are the top 4 reasons to publish clinical case reports Open Access: Everyone can learn about interesting and unique disease manifestations and diagnostic methods, Everyone can get an invaluable first-hand source of evidence about general and novel therapeutic approaches across the globe, It helps to discover life threatening adverse reactions to medications, Used in practice to exchange information and generate a more expanded search for evidence We hereby would like to encourage every medical doctor, nurse and health care professional to share their clinical knowledge and discuss openly and cross-border their thoughts to generate new research and hypotheses. This becomes even more important with the rise of the Open Access movement and has an invaluable role in disseminating knowledge. So, welcome to the clinical case reports collection and unlock your education, doc!

scholarly journals Correction to: MAGE‑C2/CT10 promotes growth and metastasis through upregulating c‑Myc expression in prostate cancer

2020 ◽  
Author(s):  
Jun Qiu ◽  
Bei Yang
Keyword(s):  
Prostate Cancer ◽  
Open Access ◽  
Internet Portal ◽  
Creative Commons ◽  
Link Type

The article “MAGE-C2/CT10 promotes growth and metastasis through upregulating c-Myc expression in prostate cancer”, written by “Jun Qiu and Bei Yang”, was originally published electronically on the publisher's internet portal on 06 July 2020 without open access. With the author(s)' decision to opt for Open Choice the copyright of the article changed on 19 October 2020 to © The Author(s) 2020 and the article is forthwith distributed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made.

Desulfosporosinus metallidurans sp. nov., an acidophilic, metal-resistant sulfate-reducing bacterium from acid mine drainage

2021 ◽  
Vol 71 (7) ◽  
Author(s):  
Inna A. Panova ◽  
Olga Ikkert ◽  
Marat R. Avakyan ◽  
Dmitry S. Kopitsyn ◽  
Andrey V. Mardanov ◽  
...  
Keyword(s):  
Mine Drainage ◽  
Sequence Similarity ◽  
Cell Structure ◽  
Draft Genome ◽  
Electron Acceptors ◽  
Rrna Gene ◽  
Protein Coding ◽  
Content Type ◽  
Sulfate Reducing ◽  
Link Type

A novel, spore-forming, acidophilic and metal-resistant sulfate-reducing bacterium, strain OLT, was isolated from a microbial mat in a tailing dam at a gold ore mining site. Cells were slightly curved immotile rods, 0.5 µm in diameter and 2.0–3.0 µm long. Cells were stained Gram-negative, despite the Gram-positive cell structure revealed by electron microscopy of ultrathin layers. OLT grew at pH 4.0–7.0 with an optimum at 5.5. OLT utilised H2, lactate, pyruvate, malate, formate, propionate, ethanol, glycerol, glucose, fructose, sucrose, peptone and tryptone as electron donors for sulfate reduction. Sulfate, sulfite, thiosulfate, nitrate and fumarate were used as electron acceptors in the presence of lactate. Elemental sulfur, iron (III), and arsenate did not serve as electron acceptors. The major cellular fatty acids were C16:1ω7c (39.0 %) and C16 : 0 (12.1 %). The draft genome of OLT was 5.29 Mb in size and contained 4909 protein-coding genes. The 16S rRNA gene sequence placed OLT within the phylum Firmicutes , class Clostridia , family Peptococcaceae , genus Desulfosporosinus. Desulfosporosinus nitroreducens 59.4BT was the closest relative with 97.6 % sequence similarity. On the basis of phenotypic and phylogenetic characteristics, strain OLT represents a novel species within the genus Desulfosporosinus , for which we propose the name Desulfosporosinus metallidurans sp. nov. with the type strain OLT (=DSM 104464T=VKM В−3021T).

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