Four EBNA2 Domains Are Important for EBNALP Coactivation
2004 ◽
Vol 78
(20)
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pp. 11439-11442
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Keyword(s):
ABSTRACT EBNA2 transcriptional activation and regulated EBNALP coactivation are critical for Epstein-Barr virus-infected primary B-lymphocyte growth transformation. EBNALP coactivation requires the EBNA2 acidic activation domain (E2AD); EBNALP can bind to E2AD. EBNALP has now been found to bind less well to EBNA2 amino acids 1 to 58, which has been identified to be a second transcriptional activation domain, E2AD2. E2AD2 was specifically coactivated by EBNALP. Moreover, E2AD, E2AD2, EBNA2 RG domain, and the intermediate domain between RG and E2AD had significant roles in EBNA2-mediated activation and EBNALP coactivation.
1998 ◽
Vol 72
(11)
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pp. 8559-8567
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1999 ◽
Vol 73
(12)
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pp. 10525-10530
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Keyword(s):
Keyword(s):
1999 ◽
Vol 19
(3)
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pp. 1617-1626
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1997 ◽
Vol 71
(9)
◽
pp. 6547-6554
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1997 ◽
Vol 17
(1)
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pp. 115-122
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