scholarly journals Influenza A H1N1 Induced Disturbance of the Respiratory and Fecal Microbiome of German Landrace Pigs – a Multi-Omics Characterization

2021 ◽  
Author(s):  
Laurin Christopher Gierse ◽  
Alexander Meene ◽  
Daniel Schultz ◽  
Theresa Schwaiger ◽  
Charlotte Schröder ◽  
...  
Keyword(s):  
Influenza A ◽  
Structure And Function ◽  
Biomedical Model ◽  
H1n1 Infection ◽  
Gastrointestinal Microbiome ◽  
Fecal Microbiome ◽  
Influenza A H1n1 ◽  
Influenza A Virus Infection ◽  
And Function ◽  
The Impact

Here, we used swine as a biomedical model to elucidate the impact of influenza A H1N1 infection on structure and function of the respiratory and gastrointestinal tract microbiome by employing a multi-omics analytical approach. To our knowledge, this is the first study to investigate the temporal development of the porcine microbiome and to provide insights into the functional capacity of the gastrointestinal microbiome during influenza A virus infection.

scholarly journals Long-Term Neuroinflammation Induced by Influenza A Virus Infection and the Impact on Hippocampal Neuron Morphology and Function

2018 ◽  
Vol 38 (12) ◽  
pp. 3060-3080 ◽  
Author(s):  
Shirin Hosseini ◽  
Esther Wilk ◽  
Kristin Michaelsen-Preusse ◽  
Ingo Gerhauser ◽  
Wolfgang Baumgärtner ◽  
...  
Keyword(s):  
Virus Infection ◽  
Influenza A Virus ◽  
Influenza A ◽  
Hippocampal Neuron ◽  
Neuron Morphology ◽  
Influenza A Virus Infection ◽  
And Function ◽  
The Impact

The Laryngeal Epithelium in Reflux

2011 ◽  
Vol 21 (3) ◽  
pp. 112-117 ◽  
Author(s):  
Elizabeth Erickson-Levendoski ◽  
Mahalakshmi Sivasankar
Keyword(s):  
Laryngopharyngeal Reflux ◽  
Critical Role ◽  
Structure And Function ◽  
Laryngeal Disease ◽  
Health And Disease ◽  
And Function ◽  
The Impact

The epithelium plays a critical role in the maintenance of laryngeal health. This is evident in that laryngeal disease may result when the integrity of the epithelium is compromised by insults such as laryngopharyngeal reflux. In this article, we will review the structure and function of the laryngeal epithelium and summarize the impact of laryngopharyngeal reflux on the epithelium. Research investigating the ramifications of reflux on the epithelium has improved our understanding of laryngeal disease associated with laryngopharyngeal reflux. It further highlights the need for continued research on the laryngeal epithelium in health and disease.

scholarly journals Metagenomic Analysis of the Fecal Archaeome in Suckling Piglets Following Perinatal Tulathromycin Metaphylaxis

Animals ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1825
Author(s):  
Mohamed Zeineldin ◽  
Ameer Megahed ◽  
Benjamin Blair ◽  
Brian Aldridge ◽  
James Lowe
Keyword(s):  
Sequencing Analysis ◽  
Metagenomic Sequencing ◽  
Post Intervention ◽  
Gastrointestinal Microbiome ◽  
Health And Wellbeing ◽  
Suckling Piglets ◽  
And Function ◽  
Changes Over Time ◽  
And Control ◽  
The Impact

The gastrointestinal microbiome plays an important role in swine health and wellbeing, but the gut archaeome structure and function in swine remain largely unexplored. To date, no metagenomics-based analysis has been done to assess the impact of an early life antimicrobials intervention on the gut archaeome. The aim of this study was to investigate the effects of perinatal tulathromycin (TUL) administration on the fecal archaeome composition and diversity in suckling piglets using metagenomic sequencing analysis. Sixteen litters were administered one of two treatments (TUL; 2.5 mg/kg IM and control (CONT); saline 1cc IM) soon after birth. Deep fecal swabs were collected from all piglets on days 0 (prior to treatment), 5, and 20 post intervention. Each piglet’s fecal archaeome was composed of rich and diverse communities that showed significant changes over time during the suckling period. At the phylum level, 98.24% of the fecal archaeome across all samples belonged to Euryarchaeota. At the genus level, the predominant archaeal genera across all samples were Methanobrevibacter (43.31%), Methanosarcina (10.84%), Methanococcus (6.51%), and Methanocorpusculum (6.01%). The composition and diversity of the fecal archaeome between the TUL and CONT groups at the same time points were statistically insignificant. Our findings indicate that perinatal TUL metaphylaxis seems to have a minimal effect on the gut archaeome composition and diversity in sucking piglets. This study improves our current understanding of the fecal archaeome structure in sucking piglets and provides a rationale for future studies to decipher its role in and impact on host robustness during this critical phase of production.

Nosocomial Influenza in a Pediatric Hospital: Comparison of Rates of Seasonal and Pandemic 2009 Influenza A/H1N1 Infection

2012 ◽  
Vol 33 (3) ◽  
pp. 292-294 ◽  
Author(s):  
Gholamabbas Amin Ostovar ◽  
Nina Kohn ◽  
Karl O. A. Yu ◽  
Susan Nullet ◽  
Lorry G. Rubin
Keyword(s):  
Influenza A ◽  
Infect Control Hosp ◽  
H1n1 Infection ◽  
Pediatric Hospital ◽  
Children's Hospital ◽  
Influenza A H1n1 ◽  
Children’S Hospital ◽  
Hospital Comparison

The rates of nosocomial seasonal (January 2008 to March 2009) and 2009 A/H1N1 (April 2009 to December 2010) influenza infections in a children's hospital were compared. Droplet precautions were used. The rates were similar during both periods, suggesting that use of droplet precautions did not result in a higher rate of influenza A/H1N1 infection.Infect Control Hosp Epidemiol 2012;33(3):292-294

scholarly journals Influenza A(H1N1) infection and severe cardiac dysfunction in adults: A case series

2011 ◽  
Vol 123 (3-4) ◽  
pp. 120-123 ◽  
Author(s):  
Jan A. Wiegand ◽  
Christian Torgersen ◽  
Stefan Bloechlinger ◽  
Jukka Takala ◽  
Martin W. Dünser
Keyword(s):  
Cardiac Dysfunction ◽  
Influenza A ◽  
Case Series ◽  
H1n1 Infection ◽  
Influenza A H1n1

scholarly journals Serum activin A and B, and follistatin in critically ill patients with influenza A(H1N1) infection

2014 ◽  
Vol 14 (1) ◽  
Author(s):  
Rita Linko ◽  
Mark P Hedger ◽  
Ville Pettilä ◽  
Esko Ruokonen ◽  
Tero Ala-Kokko ◽  
...  
Keyword(s):  
Critically Ill ◽  
Critically Ill Patients ◽  
Influenza A ◽  
Activin A ◽  
H1n1 Infection ◽  
Influenza A H1n1

Assessment of the impact of nanoparticles on the activity of biomimetic membrane

2021 ◽  
Vol XXXVII (1) ◽  
pp. 89-100
Author(s):  
Dorota Kondej
Keyword(s):  
Occupational Safety ◽  
Biological Membranes ◽  
Structure And Function ◽  
Lipid Monolayer ◽  
Biomimetic Membranes ◽  
Safety And Health ◽  
Biomimetic Membrane ◽  
And Function ◽  
The Impact

This paper presents basic information on a structure and function of biological membranes. Types of biomimetic membranes modelling properties of biological membranes were introduced. The method of testing surface properties of a lipid monolayer, which is the basic type of biomimetic membranes, was described. The presented method makes it possible to evaluate the effect of nanoparticles on the surface activity of biomimetic membranes based on the determination of the surface index MA. This article discusses the problems of occupational safety and health, which are covered by health sciences and environmental engineering.

scholarly journals Estrogen-related Receptor β (ERRβ) – Renaissance Receptor or Receptor Renaissance?

2016 ◽  
Vol 14 (1) ◽  
pp. nrs.14002 ◽  
Author(s):  
Shailaja D. Divekar ◽  
Deanna M. Tiek ◽  
Aileen Fernandez ◽  
Rebecca B. Riggins
Keyword(s):  
Alternative Splicing ◽  
Nuclear Receptor ◽  
Family Members ◽  
Structure And Function ◽  
The Other ◽  
Orphan Nuclear Receptor ◽  
Nuclear Receptor Superfamily ◽  
And Function ◽  
The Impact ◽  
Estrogen Related Receptor

Estrogen-related receptors (ERRs) are founding members of the orphan nuclear receptor (ONR) subgroup of the nuclear receptor superfamily. Twenty-seven years of study have yet to identify cognate ligands for the ERRs, though they have firmly placed ERRα (ESRRA) and ERRγ (ESRRG) at the intersection of cellular metabolism and oncogenesis. The pace of discovery for novel functions of ERRβ (ESRRB), however, has until recently been somewhat slower than that of its family members. ERRβ has also been largely ignored in summaries and perspectives of the ONR literature. Here, we provide an overview of established and emerging knowledge of ERRβ in mouse, man, and other species, highlighting unique aspects of ERRβ biology that set it apart from the other two estrogen-related receptors, with a focus on the impact of alternative splicing on the structure and function of this receptor.

Clinical Features of Hospitalized Adult Patients with Pneumonia in Novel Influenza A (H1N1) Infection

2010 ◽  
Vol 69 (1) ◽  
pp. 24 ◽  
Author(s):  
Chang Hoon Han ◽  
Yu Kyung Hyun ◽  
Yu Ri Choi ◽  
Na Young Sung ◽  
Yoon Seon Park ◽  
...  
Keyword(s):  
Clinical Features ◽  
Influenza A ◽  
Adult Patients ◽  
H1n1 Infection ◽  
Influenza A H1n1 ◽  
Novel Influenza A
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