Kinetics of Chemical Processes in the Human Brain. Proton Blockade of Acetylcholinesterase and pH-Impulse in the Mechanism of Functioning of the Cholinergic Synapse

2020 ◽  
Vol 491 (1) ◽  
pp. 85-88 ◽  
Author(s):  
S. D. Varfolomeev ◽  
V. I. Bykov ◽  
S. B. Tsybenova
2019 ◽  
Vol 488 (2) ◽  
pp. 157-161
Author(s):  
S. D. Varfolomeev ◽  
N. A. Semenova ◽  
V. I. Bykov ◽  
S. B. Tsybenova

A kinetic model describing the impulse of increasing oxygen in the excited nervous tissue of the human brain in response to an external signal is presented. The model is based on biochemical data and describes experimental data on an impulsed hemodynamic response. The model predicts the dynamic behavior of the process participants, which preceding the oxygen impulse and determining the level of the BOLD-signal.


2019 ◽  
Vol 484 (2) ◽  
pp. 23-27 ◽  
Author(s):  
S. D. Varfolomeev ◽  
N. A. Semenova ◽  
V. I. Bykov ◽  
S. B. Tsybenova

2019 ◽  
Vol 488 (1) ◽  
pp. 125-128 ◽  
Author(s):  
S. D. Varfolomeev ◽  
N. A. Semenova ◽  
V. I. Bykov ◽  
S. B. Tsybenova

1991 ◽  
Vol 238 ◽  
Author(s):  
G. J. Shiflet

ABSTRACTStresses are introduced in crystals at interphase boundaries where steps improve the registry of atoms. A model and mathematical analysis based on an approach previously taken by van der Merwe and Shiflet1–4 of the problem incorporating a coherent step are presented. Computed distributions of stresses, strains, dilatation and energy density in the form of contours and nets are given for a coherent monatomic step. It is concluded that the maximum stresses are quite large and the fields decay fairly rapidly with distance from the steps, the gradient of dilatation around steps will significantly affect diffusion kinetics of impurities and the strain energy seems too low to significantly enhance chemical processes.


2018 ◽  
Vol 3 (3) ◽  
pp. 230
Author(s):  
Salakhova A.A. ◽  
Suvorov V.A. ◽  
Firsova A. I. ◽  
Belozerov V.I. ◽  
Milinchuk V.K.

The results of investigations of the kinetics of hydrogen generation compositions with aluminum, chemical activators (hydrated sodium metasilicate, oxide and calcium hydroxide) boric acid. Aluminium and its alloys used for the manufacture of protective sheaths of fuel elements and control rod protection system management, pipelines, tanks, and various support structures in the active zone of atomic reactors RBMK, research water-cooled reactors. The aluminum is protected from direct contact with water and steam surface layer of metal oxide having a high corrosion resistance at high temperatures in powerful radiation fields. However, after removal or when the discontinuity of the oxide layer of activated metal efficiently decompose water to hydrogen. It is established that the hydrogen aluminum-containing compositions is dependent on the concentration of boric acid. The discovery of the involvement of boric acid in these reactions expands the ideas about regularities of chemical processes of formation of hydrogen flowing in the water coolant of VVER reactors with the participation of the corrective additives and impurities.


1997 ◽  
Vol 51 (1) ◽  
pp. 74-80 ◽  
Author(s):  
Peter Jacob ◽  
Bernhard Wehling ◽  
Wieland Hill ◽  
Dieter Klockow

The described investigations are focused on peroxides occurring as products in atmospheric chemical processes, namely, hydrogen peroxide, methylhydroperoxide, hydroxymethylhydroperoxide, bis-(hydroxymethyl)peroxide, 1-hydroxyethylhydroperoxide, bis-(hydroxyethyl)peroxide, and hydroxymethylmethylperoxide. The compounds are identified and determined through the position and intensity of their characteristic O–O stretching bands in the range between 767 and 878 cm−1. Time-resolved Raman spectroscopy of peroxide solutions permits the in situ investigation of pathways and kinetics of reactions between peroxides and aldehydes.


1996 ◽  
Vol 35 (6) ◽  
pp. 841-856
Author(s):  
E. F. Vainshtein ◽  
G. E. Zaikov

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