The association between objectively measured physical activity and knee structural change using MRI

ObjectivesThis study describes the longitudinal association between objectively assessed physical activity (PA) and knee structural change measured using MRI.Methods405 community-dwelling adults aged 51–81 years were measured at baseline and approximately 2.7 years later. MRI of the right knee at baseline and follow-up was performed to evaluate bone marrow lesions (BMLs), meniscal pathology, cartilage defects, and cartilage volume. PA was assessed at baseline by pedometer (steps/day).ResultsDoing ≥10 000 steps/day was associated with BML increases (RR 1.97, 95% CI 1.19 to 3.27, p=0.009). Participants doing ≥10 000 steps/day had a 1.52 times (95% CI 1.05 to 2.20, p=0.027) greater risk of increasing meniscal pathology score, which increased to 2.49 (95% CI 1.05 to 3.93, p=0.002) in those with adverse meniscal pathology at baseline. Doing ≥10 000 steps/day was associated with a greater risk of increasing cartilage defect score in those with prevalent BMLs at baseline (RR 1.36, 95% CI 1.03 to 1.69, p=0.013). Steps/day was protective against volume loss in those with more baseline cartilage volume but led to increased cartilage loss in those with less baseline cartilage volume. (p=0.046 for interaction).ConclusionsPA was deleteriously associated with knee structural change, especially in those with pre-existing knee structural abnormalities. This suggests individuals with knee abnormalities should avoid doing ≥10 000 steps/day. Alternatives to weight-bearing activity may be needed in order to maintain PA levels required for other aspects of health.

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Changes in Objectively Measured Lifestyle Factors During the COVID-19 Pandemic in Community-Dwelling Older Adults

10.21203/rs.3.rs-847301/v1 ◽

2021 ◽

Author(s):

Takuya Ataka ◽

Noriyuki Kimura ◽

Atsuko Eguchi ◽

Etsuro Matsubara

Keyword(s):

Physical Activity ◽

Older Adults ◽

Sedentary Time ◽

Vigorous Physical Activity ◽

Wearable Sensors ◽

Lifestyle Factors ◽

Community Dwelling ◽

Activity Level ◽

Objectively Measured ◽

Community Dwelling Older Adults

Abstract Background: In this manuscript, we aimed at investigating whether objectively measured lifestyle factors, including walking steps, sedentary time, amount of unforced physical activity, level of slight and energetic physical activity, conversation time, and sleep parameters altered before and during the COVID-19 pandemic among community-dwelling older adults.Methods: Data were obtained from a prospective cohort study conducted from 2015 to 2019 and a subsequent dementia prevention study undertaken in September 2020. Community-dwelling adults aged ≥65 years wore wearable sensors before and during the pandemic.Results: A total of 56 adults were enrolled in this study. The mean age was 74.2±3.9 years, and 58.9% (n=33) of the participants were female. The moderate and vigorous physical activity time significantly decreased and sedentary time significantly increased during the pandemic. Conclusions: This is the first study to demonstrate differences in objectively assessed lifestyle factors before and during the COVID-19 pandemic among community-dwelling older adults. The findings show that the pandemic has adversely affected physical activity among older adults living on their own in Japan.

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Every step counts: synthesising reviews associating objectively measured physical activity and sedentary behaviour with clinical outcomes in community-dwelling older adults

The Lancet Healthy Longevity ◽

10.1016/s2666-7568(21)00203-8 ◽

2021 ◽

Vol 2 (11) ◽

pp. e764-e772

Author(s):

Keenan A Ramsey ◽

Carel G M Meskers ◽

Andrea B Maier

Keyword(s):

Physical Activity ◽

Older Adults ◽

Sedentary Behaviour ◽

Clinical Outcomes ◽

Community Dwelling ◽

Step Counts ◽

Objectively Measured ◽

Community Dwelling Older Adults ◽

Objectively Measured Physical Activity

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Association of Perceived Built Environment Attributes with Objectively Measured Physical Activity in Community-Dwelling Ambulatory Patients with Stroke

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph16203908 ◽

2019 ◽

Vol 16 (20) ◽

pp. 3908

Author(s):

Masashi Kanai ◽

Kazuhiro P. Izawa ◽

Hiroki Kubo ◽

Masafumi Nozoe ◽

Kyoshi Mase ◽

...

Keyword(s):

Physical Activity ◽

Built Environment ◽

Vigorous Physical Activity ◽

Linear Regression Analysis ◽

Multiple Linear Regression Analysis ◽

Community Dwelling ◽

Cross Sectional ◽

Ambulatory Patients ◽

Objectively Measured ◽

Objectively Measured Physical Activity

There is little evidence on how perceptions of the built environment may influence physical activity among post-stroke patients. This study aimed to explore the associations between perceived built environment attributes and objectively measured physical activity outcomes in community-dwelling ambulatory patients with stroke. This cross-sectional study recruited patients who could walk outside without assistance. We assessed both objectively measured physical activity outcomes such as number of steps and duration of moderate-to-vigorous physical activity (MVPA) with an accelerometer and the patients’ perceived surrounding built environment with the International Physical Activity Questionnaire Environmental Module. Sixty-one patients (67.0 years old) were included. The multiple linear regression analysis showed significant associations of the presence of sidewalks (β = 0.274, p = 0.016) and access to recreational facilities (β = 0.284, p = 0.010) with the number of steps taken (adjusted R2 = 0.33). In contrast, no significant associations were found between perceived built environment attributes and MVPA. These findings may help to suggest an approach to promote appropriate physical activity in patients with stroke depending on their surrounding built environment.

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Lazy Sundays: role of day of the week and reactivity on objectively measured physical activity in older people

European Review of Aging and Physical Activity ◽

10.1186/s11556-019-0226-1 ◽

2019 ◽

Vol 16 (1) ◽

Cited By ~ 1

Author(s):

Jochen Klenk ◽

◽

Raphael Simon Peter ◽

Kilian Rapp ◽

Dhayana Dallmeier ◽

...

Keyword(s):

Physical Activity ◽

Older People ◽

Community Dwelling ◽

Activity Level ◽

Least Square ◽

Significant Difference ◽

Day Of The Week ◽

Linear Slope ◽

Objectively Measured ◽

Objectively Measured Physical Activity

Abstract Background The aim of this study was to assess the effect of day of the week and wearing a device (reactivity) on objectively measured physical activity (PA) in older people. Methods Walking duration as a measure for PA was recorded from 1333 German community-dwelling older people (≥65 years, 43.8% women) over 5 days using accelerometers (activPAL). Least-square means of PA with 95%-confidence intervals (95%-CI) from multi-level analysis were calculated for each day of the week and each measurement day (days after sensor attachment). Results Walking duration on Sundays was significantly lower compared to working days (Sunday vs. Monday-Friday: − 12.8 min (95%-CI: − 14.7; − 10.9)). No statistically significant difference compared to working days was present for Saturdays. The linear slope for measurement day and walking duration was marginal and not statistically significant. Conclusions Studies using PA sensors in older people should assess Sundays and working days to adequately determine the activity level of the participants.

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Concurrent Validity Between Electronically Administered Physical Activity Questionnaires and Objectively Measured Physical Activity in Danish Community-Dwelling Older Adults

Journal of Aging and Physical Activity ◽

10.1123/japa.2020-0214 ◽

2020 ◽

pp. 1-9

Author(s):

Rasmus T. Larsen ◽

Christoffer B. Korfitsen ◽

Carsten B. Juhl ◽

Henning Boje Andersen ◽

Henning Langberg ◽

...

Keyword(s):

Physical Activity ◽

Older Adults ◽

Concurrent Validity ◽

Short Form ◽

Community Dwelling ◽

World Health ◽

Moderate Physical Activity ◽

Physical Activity Questionnaire ◽

Objectively Measured ◽

Activity Questionnaire

Aim: To investigate the concurrent validity of the International Physical Activity Questionnaire-short form (IPAQ-SF) and the Nordic Physical Activity Questionnaire-short (NPAQ-short) when compared with objectively measured daily steps among older adults. Methods: Spearman’s ρ between IPAQ-SF and NPAQ-short and objectively measured steps using Garmin Vivofit 3 physical activity monitors. Results: A total of 54 participants were included. The IPAQ-SF subscales’ moderate physical activity (PA), moderate to vigorous PA (MVPA), and sedentary time showed little or no correlation with daily steps. The NPAQ-short subscales’ vigorous PA, moderate PA, and MVPA showed little or no correlation. The IPAQ-SF subscales’ vigorous PA and walking showed fair correlation. Only the IPAQ-SF metabolic equivalent of task minutes showed moderate to good correlation with daily steps. The IPAQ-SF categories and NPAQ-short categorization of World Health Organization compliance were significantly different, but the magnitudes were small and distributions indicated problems with the categorization. Conclusion: The concurrent validity is low, as the scores did not reflect objectively measured daily steps.

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Effect of Autologous Platelet Rich Fibrin on the Healing of Experimental Articular Cartilage Defects of the Knee in an Animal Model

BioMed Research International ◽

10.1155/2014/486436 ◽

2014 ◽

Vol 2014 ◽

pp. 1-10 ◽

Cited By ~ 18

Author(s):

Davoud Kazemi ◽

Ashraf Fakhrjou ◽

Vahid Mirzazadeh Dizaji ◽

Majid Khanzadeh Alishahi

Keyword(s):

Animal Model ◽

Articular Cartilage ◽

Hind Limb ◽

Weight Bearing ◽

Cartilage Defects ◽

Platelet Rich Fibrin ◽

Cartilage Lesions ◽

Hind Limbs ◽

The Right ◽

Autologous Platelet

The effect of autologous platelet rich fibrin (PRF), a second generation platelet product, on the healing of experimental articular cartilage lesions was evaluated in an animal model. Full thickness cartilage lesions with a diameter of 6 mm and depth of 5 mm were created in the weight bearing area of femoral condyles of both hind limbs in 12 adult mixed breed dogs. Defects in the left hind limb of each dog were repaired by PRF implantation whereas those in the right hind limb were left empty. The animals were euthanized at 4, 16, and 24 weeks following surgery and the resultant repair tissue was investigated macroscopically and microscopically. The results of macroscopic and histological evaluations indicated that there were significant differences between the PRF treated and untreated defects. In conclusion, the present study indicated that the use of platelet rich fibrin as a source of autologous growth factors leads to improvement in articular cartilage repair.

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