FRI0097 Factors Associated with Major Depressive Disorder in Rheumatoid Arthritis Patients

IntroductionDrinking has been shown to be a protective factor against the risk of rheumatoid arthritis (RA). On the other hand, high prevalence of depressive symptoms has been observed among RA patients.ObjectiveTo evaluate the association between depressive symptoms and somatic factors as well as drinking habits in RA patients.MethodsDrinking habits and physical symptoms in 182 female RA outpatients in Ivanovo, Russia (average [standard deviation] of age, 62.0 [11.7] years), were investigated. Drinking status was classified as current drinkers (alcohol consumption within the previous 12 months) and others. Depressive symptoms were evaluated with MINI, HADS and CES-D questionnaires. Outcomes were (a) presence or history of major depressive disorder, presence of melancholic major depressive disorder, presence of dysthymia, or 1 point or greater of suicidal risk score in MINI, (b) 8 points or greater in HADS-depression, (c) 8 points or greater in HADS-anxiety, and (d) 16 points or greater in CES-D. Stepwise logistic regression was used to evaluate somatic factors associated with depressive symptoms, with age and drinking status included.ResultsDrinking was rather protective against depression, but did not reach statistical significance. Symptomatic parts in the extremities associated with the outcomes were shoulders for MINI, elbows and knees for HADS-depression, shoulders for HADS-anxiety, and hands, elbows and shoulders for CES-D. In the stepwise selection, some symptoms in the extremities were positively associated with the outcomes.ConclusionSymptoms chiefly in large joints contributed to depressive symptoms.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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Predictors of Major Depressive Disorder in Older People

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph182211894 ◽

2021 ◽

Vol 18 (22) ◽

pp. 11894

Author(s):

Susana Sousa ◽

Constança Paúl ◽

Laetitia Teixeira

Keyword(s):

Major Depressive Disorder ◽

Depressive Disorder ◽

Older People ◽

Social Factors ◽

Common Mental Disorders ◽

Community Dwelling ◽

Major Depressive ◽

Factors Associated ◽

Status Mobility ◽

Community Dwelling Older People

Major depressive disorder (MDD) is one of the most common mental disorders in older people. There are several biological, psychological, and social factors associated with this disorder. This study aimed to describe the depressive state to identify the associated factors and potential predictors of MDD in a population of community-dwelling older people with probable MDD. The sample consisted of 378 participants with probable dementia, with 47.3% of them presenting MDD. The factors that were found to be associated with MDD were sex, living status, mobility, and nutritional status. Knowing the factors that can predict a condition such as MDD is extremely important, both for prevention and for the customization of interventions.

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Occupational factors associated with major depressive disorder: A Brazilian population-based study

Journal of Affective Disorders ◽

10.1016/j.jad.2018.07.022 ◽

2018 ◽

Vol 240 ◽

pp. 48-56 ◽

Cited By ~ 9

Author(s):

Nágila Soares Xavier Oenning ◽

Patrícia Klarmann Ziegelmann ◽

Bárbara Niegia Garcia de Goulart ◽

Isabelle Niedhammer

Keyword(s):

Major Depressive Disorder ◽

Depressive Disorder ◽

Population Based ◽

Brazilian Population ◽

Major Depressive ◽

Population Based Study ◽

Occupational Factors ◽

Factors Associated

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Factors associated with 30-day readmissions following medical hospitalizations among Medicaid beneficiaries with schizophrenia, bipolar disorder, and major depressive disorder

Psychiatry Research ◽

10.1016/j.psychres.2020.113168 ◽

2020 ◽

Vol 291 ◽

pp. 113168

Author(s):

Judith A. Cook ◽

Jane K. Burke-Miller ◽

Jessica A. Jonikas ◽

Frances Aranda ◽

Alberto Santos

Keyword(s):

Bipolar Disorder ◽

Major Depressive Disorder ◽

Depressive Disorder ◽

Major Depressive ◽

Factors Associated ◽

Medicaid Beneficiaries

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Extent and Factors Associated with Adherence to Antidepressant Treatment During Acute and Continuation Phase Depression Treatment Among Older Adults with Dementia and Major Depressive Disorder

Neuropsychiatric Disease and Treatment ◽

10.2147/ndt.s241749 ◽

2020 ◽

Vol Volume 16 ◽

pp. 1433-1450

Author(s):

Sandipan Bhattacharjee ◽

Jeannie K Lee ◽

Nina Vadiei ◽

Asad E Patanwala ◽

Daniel C Malone ◽

...

Keyword(s):

Older Adults ◽

Major Depressive Disorder ◽

Depressive Disorder ◽

Antidepressant Treatment ◽

Depression Treatment ◽

Major Depressive ◽

Continuation Phase ◽

Factors Associated

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Predictors of 1-year outcomes of major depressive disorder among individuals with a lifetime diagnosis: a population-based study

Psychological Medicine ◽

10.1017/s0033291711001218 ◽

2011 ◽

Vol 42 (2) ◽

pp. 327-334 ◽

Cited By ~ 14

Author(s):

J. L. Wang ◽

S. B. Patten ◽

S. Currie ◽

J. Sareen ◽

N. Schmitz

Keyword(s):

Major Depressive Disorder ◽

Depressive Disorder ◽

Longitudinal Studies ◽

Psychosocial Factors ◽

Composite International Diagnostic Interview ◽

Population Based ◽

World Health ◽

Major Depressive ◽

Factors Associated ◽

Lifetime Diagnosis

BackgroundExamining predictors of the outcomes of major depressive disorder (MDD) is important for clinical practice and population health. There are few population-based longitudinal studies on this topic. The objectives of this study were to (1) estimate the proportions of persistent and recurrent MDD among those with MDD over 1 year, and (2) identify demographic, socio-economic, workplace psychosocial and clinical factors associated with the outcomes.MethodFrom a population-based longitudinal study of the working population, participants with a lifetime diagnosis of MDD were selected (n=834). They were classified into two groups: those with and those without current MDD. The proportions of 1-year persistence and recurrence of MDD were estimated. MDD was assessed by the World Health Organization (WHO) Composite International Diagnostic Interview, CIDI-Auto 2.1, by telephone.ResultsThe proportions of persistent and recurrent MDD in 1 year were 38.5% [95% confidence interval (CI) 31.1–46.5] and 13.3% (95% CI 10.2–17.1) respectively. Long working hours, negative thinking and having co-morbid social phobia were predictive of persistence of MDD. Perceived work–family conflict, the severity of a major depressive episode and symptoms of depressed mood were significantly associated with the recurrence of MDD.ConclusionsClinical and psychosocial factors are important in the prognosis of MDD. The factors associated with persistence and recurrence of MDD may be different. More large longitudinal studies on this topic are needed so that clinicians may predict potential outcomes based on the clinical profile and provide interventions accordingly. They may also take clinical action to change relevant psychosocial factors to minimize the chance of persistence and/or recurrence of MDD.

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Factors associated with frovatriptan response in patients with migraine: A prospective, observational study

Cephalalgia ◽

10.1177/0333102415596443 ◽

2015 ◽

Vol 36 (5) ◽

pp. 493-498 ◽

Cited By ~ 3

Author(s):

Jong-Geun Seo ◽

Sung-Pa Park

Keyword(s):

Major Depressive Disorder ◽

Risk Factor ◽

Observational Study ◽

Confidence Interval ◽

Depressive Disorder ◽

Odds Ratio ◽

Prospective Observational Study ◽

Major Depressive ◽

Factors Associated ◽

Headache Clinic

Background Almost one-third of patients with migraine do not adequately respond to triptans. We examined factors contributing to frovatriptan response in patients with migraine. Methods We enrolled new patients with migraine who consecutively visited our headache clinic. Eligible patients were instructed to take 2.5 mg of frovatriptan as soon as possible after migraine attack. The responsiveness was determined by whether headache was relieved or absent within 4 hours after the intake of frovatriptan. We assessed frovatriptan to be efficacious when headache responded to its administration in at least one of two successive migraine attacks and inefficacious when headache was not relieved in either attack. We included demographic, clinical and psychiatric variables in the analysis of factors associated with frovatriptan response. Results Of 128 eligible patients, 28 (21.9%) experienced frovatriptan inefficacy. In 24 patients with current major depressive disorder, 12 (50.0%) had frovatriptan inefficacy. Only current major depressive disorder was identified as a risk factor for inefficacy (odds ratio = 5.500, 95% confidence interval 2.103–14.382, p = 0.001). Conclusions Depression may be a risk factor of frovatriptan inefficacy in patients with migraine, even though half of patients with major depressive disorder respond to frovatriptan.

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