The One-portal System: A Historical Study: III.--The Royal Commission of 1881 and the Act of 1886

BMJ ◽  
1898 ◽  
Vol 1 (1941) ◽  
pp. 720-721
Keyword(s):  
Portal System ◽  
Historical Study ◽  
Royal Commission ◽  
System A ◽  
The One

Purification of a Specific Placental Plasminogen Activator Inhibitor by Monoclonal Antibody and Its Complex Formation with Plasminogen Activator

1985 ◽  
Vol 53 (01) ◽  
pp. 122-125 ◽  
Author(s):  
B Åstedt ◽  
Ingegerd Lecander ◽  
T Brodin ◽  
A Lundblad ◽  
Karin Löw
Keyword(s):  
Monoclonal Antibody ◽  
Complex Formation ◽  
Plasminogen Activator ◽  
Plasminogen Activator Inhibitor ◽  
Tissue Type ◽  
System A ◽  
The One ◽  
Fast Acting ◽  
Chain Form ◽  
Activator Inhibitor

SummaryA monoclonal antibody of IgG2a-type was obtained against a specific fast acting plasminogen activator inhibitor found in placenta. The placental inhibitor was purified by affinity chromatography using the monoclonal antibody and additionally in a FPLC-system. A strong complex formation was found between the inhibitor and urokinase and also with the two-chain form of plasminogen activator of the tissue-type. A weaker complex was found between the placental inhibitor and the one- chain form of the tissue-type activator.

Clinical Notes on Haemorrhages in General Paralysis

1886 ◽  
Vol 31 (136) ◽  
pp. 504-507
Author(s):  
Geo. H. Savage
Keyword(s):  
Nervous System ◽  
Nervous Disease ◽  
General Paralysis ◽  
Clinical Notes ◽  
System A ◽  
General Pathology ◽  
Mental Symptoms ◽  
The One ◽  
Nutritional Changes

In so-called nervous disorders it is common to find changes occur in other of the bodily systems than the nervous. The pathology of nervous disease should be looked upon as a general pathology, and it is certain that we cannot look to the one system alone for causes of all the nervous disorders without greatly misunderstanding the whole subject. The more exact we become in limiting the causes, the more liable are we to error. We are all prepared to consider general paralysis of the insane as essentially a disease of the nervous system, a disease in which nearly every part of the nervous system may suffer sooner or later. But beside the essentially nervous symptoms which occur in the disease, we are constantly struck by the regular series of nutritional changes which occur in general paralysis, and this is so much the case that we are quite prepared to recognise as general paralysis a disorder in which any mental symptoms have been present, but have after a brief period of acuteness been followed by a state of fatness and weak-mindedness which again has been followed by a period of wasting and further mental weakness. We have here nervous symptoms related very directly with nutritional changes.

Man, Institutions and Bioeconomics

2003 ◽  
Vol 14 (4) ◽  
pp. 339-355
Author(s):  
Javier Alfonso Gil
Keyword(s):  
Methodological Approach ◽  
Natural Habitat ◽  
Social Technology ◽  
Activity System ◽  
Material Technology ◽  
Political Market ◽  
System A ◽  
Biological Capacity ◽  
Growth Of Knowledge ◽  
The One

Because bioeconomics is born of the interaction between the biological activity system and its socio-economic activity system, a holistic methodological approach is essential to study the relations between them. However, it must search for increasing levels of reductionism within each discipline to delve into the ultimate nature of each one of the intervening forces, whether economic or biological. This paper explores the economic forces. Through the biological capacity to comprehend, man and by extension, society, accumulates knowledge, the fulcrum from which he is able to dominate over his natural habitat. From this ‘point d’appui’, man builds two basic tools to assist him in achieving the goal of bettering his social condition. On the one hand, he creates institutions that allow him to “live with others” and, on the other, he develops technology that helps him to “live better with others”. Institutions, also referred to as ‘social technology’, tend toward stability over time while technology or ‘material technology’, tends toward instability, which would suggest that, normally, the mechanics of change will originate in material technology and, from there, progress to social technology by way of the political market. The level of progress and development attained depends on the quantity and rate of growth of knowledge applied by a society. In the process, man and his collectivity are forced to adopt new views of their environment through new shared mental models. The concurrence of equipment and political market will ultimately become the prime mover of institutional and economic change as well as change in mentality. Both technologies must keep on an adaptive course of stable evolution since discrepancies arising between them can cause tension between the various social groups. Adequate management of technological shock is essential to avoid extreme situations of social conflict. Herein lie the most important political decisions that a government must confront over the long term.

scholarly journals Gut microbiota and renin-angiotensin system: a complex interplay at local and systemic levels

2021 ◽  
Author(s):  
Kinga Jaworska ◽  
Mateusz Koper ◽  
Marcin Ufnal
Keyword(s):  
Gut Microbiota ◽  
Renin Angiotensin System ◽  
Gastrointestinal Diseases ◽  
Electrolyte Balance ◽  
Ample Evidence ◽  
Angiotensin System ◽  
Renin Angiotensin ◽  
System A ◽  
Potential Mediator ◽  
The One

Gut microbiota is a potent biological modulator of many physiological and pathological states. The renin-angiotensin system (RAS), including the local gastrointestinal RAS (GI RAS), emerges as a potential mediator of microbiota-related effects. The RAS is involved in cardiovascular system homeostasis, water-electrolyte balance, intestinal absorption, glycemic control, inflammation, carcinogenesis and aging-related processes. Ample evidence suggests a bidirectional interaction between the microbiome and RAS. On the one hand, gut bacteria and their metabolites may modulate GI and systemic RAS. On the other hand, changes in the intestinal habitat caused by alterations in RAS may shape microbiota metabolic activity and composition. Notably, the pharmacodynamic effects of the RAS-targeted therapies may be in part mediated by the intestinal RAS and changes in the microbiome. This review summarizes studies on gut microbiota and RAS physiology. Expanding the research on this topic may lay a foundation for new therapeutic paradigms in gastrointestinal diseases and multiple systemic disorders.

information. How do produced quantities influence the costs per unit? How can costs, calculated at different times, be compared? What is the best way to distribute the overheads? etc.. .. After the setting up of the accounting system, a long process of maturation began. This is evident, on the one hand, from the discussions of the Board of Directors and, on the other hand from the differences between the two sets of accounts approved by the Board of Directors in 1832 and 1872. The structure of the Com­ pany evolved considerably between 1832 and 1880: two mergers occurred, the first one in 1858 with Saint-Quirin, a glass manufac­ turer, and the second one in 1872 with Perret-Olivier, whose fields of activity were mining and chemistry. After the second merger, the sales figures for chemistry outstripped the sales of glass and mirrors and during this time the Company had grown to include 16 branches in France and Germany. DISCUSSIONS ON INDUSTRIAL ACCOUNTING All the questions dealing with the setting up of a management accounting system were discussed by the Boards of Directors. In most cases, the solutions were only practical ones. There never seemed any intent or desire by the Company to make any theory or any generalization of those practical solutions. Direct and indirect costs. The distinction between direct and indirect cost was made first in 1829 with regards to labor charges.9 Salaries, of which a comprehensive list is given above, will be separated into two groups: 1) Those concerning directly and specially with the manufacturing process. 2) Those concerning administration. At the end of the year, the former will be divided and included in the suitable items of expenses; then the latter will be included in the overheads. However, direct labor is likely to have included only the wages of workers having a permanent job, and excluded those of the day laborer, which are by their very nature fluctuating. In the soda factory, the majority of workers were day laborers, thus making it difficult to estimate precisely the ratio between direct and indirect labor charges. Production level and cost per unit. In the previously quoted chief accountant’s report concerning the financial year 1827-1828,

2014 ◽  
pp. 259-259
Keyword(s):  
Board Of Directors ◽  
Boards Of Directors ◽  
Indirect Costs ◽  
The Other ◽  
Production Level ◽  
Accounting System ◽  
Direct And Indirect Costs ◽  
System A ◽  
The Board Of Directors ◽  
The One

Integration of one-dimensional equations of motions

2020 ◽  
pp. 79-90
Author(s):  
Gleb L. Kotkin ◽  
Valeriy G. Serbo
Keyword(s):  
Potential Energy ◽  
Field Change ◽  
One Dimensional ◽  
System A ◽  
Small Correction ◽  
The Law ◽  
The One ◽  
The Given ◽  
Equations Of Motions

If the potential energy is independent of time, the energy of the system remains constant during the motion of a closed system. A system with one degree of freedom allows for the determination of the law of motion in quadrature. In this chapter, the authors consider motion of the particles in the one-dimensional fields. They discuss also how the law and the period of a particle moving in the potential field change due to adding to the given field a small correction.

One-Sided Control of Surge in a Centrifugal Compressor System

2000 ◽  
Author(s):  
Frank Willems ◽  
Bram de Jager
Keyword(s):  
Centrifugal Compressor ◽  
Band Pass Filter ◽  
Pass Filter ◽  
System A ◽  
Operating Region ◽  
Stable Operating ◽  
Surge Control ◽  
Small Band ◽  
Band Pass ◽  
The One

Active surge control is studied in a centrifugal compressor system. To stabilize surge, a bleed valve is applied which is nominally closed and only opens to stabilize the system around the desired operating point. This bleed valve is controlled using a linear output feedback controller based on plenum pressure measurements. In this study, the practical limitations of this one-sided surge controller are examined. Experiments show that the performance of the controller is affected by measurement noise and the desired equilibrium point in the controller, which is not accurately known in the unstable operating region. Fully-developed surge is stabilized with relatively small stationary bleed valve mass flow using the proposed controller in combination with a small band-pass filter. Measurements are compared with the results of the Greitzer model. This model shows qualitative agreement with experiments. For the examined compressor system, a 3.5% extension of the stable operating region is obtained using the one-sided surge controller.

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