scholarly journals Cross-sectional examination of the association of co-occurring alcohol misuse and traumatic brain injury on mental health and conduct problems in adolescents in Ontario, Canada

BMJ Open ◽  
2016 ◽  
Vol 6 (11) ◽  
pp. e011824 ◽  
Author(s):  
Gabriela Ilie ◽  
Robert E Mann ◽  
Angela Boak ◽  
Edward M Adlaf ◽  
Hayley Hamilton ◽  
...  
Keyword(s):  
Mental Health ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Conduct Problems ◽  
Alcohol Misuse ◽  
Cross Sectional

Rehabilitation outcomes of persons with severe traumatic brain injury: A cross-sectional survey

2021 ◽  
Vol 53 (1) ◽  
pp. 31
Author(s):  
Selvaraj Samuelkamaleshkumar ◽  
CatherineJudithHossanna ◽  
Ranjan Aruna ◽  
Suresh Annpatriciacatherine ◽  
Stephen Reethajanetsurekha ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Severe Traumatic Brain Injury ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Rehabilitation Outcomes

Mental health consequences of traumatic brain injury

2021 ◽  
Author(s):  
Jonathon R. Howlett ◽  
Lindsay D. Nelson ◽  
Murray B. Stein
Keyword(s):  
Mental Health ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Health Consequences

scholarly journals Exploring the intersection of traumatic brain injury and mental health in survivors of intimate partner violence

2021 ◽  
Vol 2 (2) ◽  
Author(s):  
Danielle Toccalino ◽  
Amy Moore ◽  
Sophia Chuon Gutierrez ◽  
Angela Colantonio ◽  
Christine M. Wickens ◽  
...  
Keyword(s):  
Mental Health ◽  
Traumatic Brain Injury ◽  
Intimate Partner Violence ◽  
Brain Injury ◽  
Partner Violence ◽  
The United States ◽  
Intimate Partner ◽  
Future Research ◽  
Heterosexual Relationships ◽  
Economic Implications

Introduction: One in four Canadian women experience intimate partner violence (IPV) in their lifetime. The COVID-19 pandemic has significantly increased rates of IPV globally and the level of violence encountered, exposing IPV survivors to greater risk of physical injury, including traumatic brain injury (TBI). Up to 75% of survivors are suspected of sustaining a TBI and 50-75% experience mental health or substance use challenges (MHSU) as a result of IPV, resulting in extensive personal, social, and economic implications. Objective: The objective of this scoping review was to synthesize what is currently known in the literature about MHSU and TBI among survivors of IPV and identify gaps. Methods: MEDLINE, EMBASE, PsycINFO, CINAHL, Cochrane, Scopus, and Web of Science were searched for relevant articles using a search strategy including text words and subject headings related to TBI, IPV, and MHSU. Two reviewers independently assessed articles for inclusion. Results: The search identified 399 unique articles, 34 of which were included in this study. Of these, 11 articles reported on MHSU in IPV-related TBI and 9 articles reported on both TBI and MHSU in IPV but did not discuss the groups together. The remainder were reviews or theses that noted MHSU in IPV-related TBI. Included articles predominantly focused on cis-gendered women in heterosexual relationships and were conducted in the United States. Only three articles focused on the experiences of Black or Indigenous women and none of the included studies discussed implications of co-occurring TBI and MHSU on survivor’s healthcare-related needs or access to care. Conclusions: Despite the high rates of co-occurring TBI and MHSU among survivors of IPV, there is little research on this intersection and no investigation of the impacts on the health system. Future research should focus on identifying the healthcare-related needs of survivors and identifying and mitigating barriers to access.

scholarly journals Factors Related To Outcome of Traumatic Brain Injury Patients at M Djamil Padang Hospital

2021 ◽  
Vol 5 (8) ◽  
pp. 811-817
Author(s):  
Nora Fitri ◽  
Syarif Indra ◽  
Hendra Permana
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Patient Outcomes ◽  
Significant Relationship ◽  
Traffic Accidents ◽  
Cross Sectional Study ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
Major Threat

Background: Traumatic brain injury is still a major threat because it can cause global morbidity and mortality. Many factors can affect the outcome of a traumatic brain injury. Some conditions that can exacerbate traumatic brain injury include GCS conditions, blood pressure variability, and pupillary reflexes.Methods: The research was conducted in M. Djamil Padang Hospital from October 2020 to March 2021. The study design was a cross-sectional study in traumatic brain injury patients with ≤ 48 hours of onset and the aged between 18-60 years. The subjects in this study consisted of 66 subjects. At 6 weeks after onset, a GOS assessment was performed to assess patient outcomes. Statistical analysis was performed computerized with SPSS 22.0. P-value <0.05 was considered statistically significant. Results: Most of the patients were male (71.2%) with an average age of 36.41 ± 14,275 years, and the most common injury mechanism was traffic accidents (95.5%). There was a significant relationship between onset of incidence, hypotension, pupillary reflexes, and Rotterdam score with the outcome of traumatic brain injury patients (p<0.05) and there was no significant relationship between age, gender, and mechanism of injury with the outcome patients with traumatic brain injury. Conclution: The onset of events, hypotension, pupillary reflexes, and Rotterdam scores significantly affect the outcome patients of traumatic brain injury.

Young Adults With Traumatic Brain Injury in Long-Term Care Homes: A Population-Based Study

2010 ◽  
Vol 11 (1) ◽  
pp. 31-36 ◽  
Author(s):  
Angela Colantonio ◽  
Dana Howse ◽  
Jigisha Patel
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Long Term Care ◽  
Secondary Data ◽  
Population Based ◽  
Care Homes ◽  
Care Needs ◽  
Cross Sectional ◽  
Term Care

AbstractThe aim of this research was to identify the number and characteristics of adults under the age of 65 with a diagnosis of traumatic brain injury (TBI) living in long-term care homes (nursing homes, homes for the aged and charitable homes) in Ontario, Canada. Methods: The study used a cross-sectional design. Secondary data analysis of a comprehensive provincial database of long-term care homes was conducted. Results: Of the 399 residents coded as having a TBI, 154 were < 65 years of age. Virtually all residents were limited in personal care and required assistance for eating (94.2%), toileting (92.2%) and dressing (99.4%). A large percentage also required care for challenging behaviours, while care needs due to substance abuse was common among 12.3% of TBI residents. Conclusion: As similar research in Australia has found, young persons in long-term care homes in Ontario, Canada, have high level personal health needs, however the appropriateness of this environment is questionable.

scholarly journals CNS disease-related protein variants as blood-based biomarkers in traumatic brain injury

Neurology ◽  
2018 ◽  
Vol 91 (15) ◽  
pp. 702-709 ◽  
Author(s):  
Stephanie M. Williams ◽  
Carrie Peltz ◽  
Kristine Yaffe ◽  
Philip Schulz ◽  
Michael R. Sierks
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Neurodegenerative Diseases ◽  
Cross Sectional Study ◽  
Single Chain ◽  
Characteristic Analysis ◽  
Cross Sectional ◽  
Increased Risk ◽  
Elisa Format ◽  
Protein Variants

ObjectiveTo utilize a panel of 11 single chain variable fragments (scFvs) that selectively bind disease-related variants of TAR DNA-binding protein (TDP)-43, β-amyloid, tau, and α-synuclein to assess damage following traumatic brain injury (TBI), and determine if the presence of protein variants could account for the increased risk of various neurodegenerative diseases following TBI.MethodsWe utilized the panel of 11 scFvs in a sensitive ELISA format to analyze sera from 43 older veterans, 25 who had experienced at least 1 TBI incident during their lifetime (∼29.4 years after TBI), and 18 controls who did not incur TBI, in a cross-sectional study.ResultsEach of the 11 scFvs individually could significantly distinguish between TBI and control samples, though they did not detect each TBI sample. Comparing the levels of all 11 variants, all 25 TBI cases displayed higher reactivity compared to the controls and receiver operating characteristic analysis revealed 100% sensitivity and specificity. Higher total protein variants levels correlated with TBI severity and with loss of consciousness. Oligomeric tau levels distinguished between single and multiple TBI incidents. While all TBI cases were readily selected with the panel, the binding pattern varied from patient to patient, suggesting subgroups that are at increased risk for different neurodegenerative diseases.ConclusionThe panel of protein variants-specific scFvs can be used to identify blood-based biomarkers indicative of TBI even 20 years or more after the initial TBI. Being able to identify subgroups of biomarker profiles allows for the possibility of individually targeted treatments.

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