scholarly journals Risk factors for gastric cancer and related serological levels in Fujian, China: hospital-based case–control study

BMJ Open ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. e042341
Author(s):  
Ping Yuan ◽  
Lan Lin ◽  
Kuicheng Zheng ◽  
Wen Wang ◽  
Sihan Wu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastric Cancer ◽  
Case Control Study ◽  
Early Stage ◽  
Case Control ◽  
Early Stage Cancer ◽  
Control Subjects ◽  
H Pylori ◽  
Pickled Vegetables ◽  
Control Study

ObjectiveTo explore the relationships between gastric cancer and serum pepsinogen I (PG I), PG II, PG I/II ratio, gastrin 17 (G-17) and Helicobacter pylori infection, and to investigate dietary and lifestyle risk factors for gastric cancer in Fujian Province, China.DesignA hospital-based, 1:1 matched case–control study.SettingPatients with newly diagnosed gastric cancer were recruited from the Fujian Provincial Hospital and the No. 900 Hospital of the Joint Support Force of the Chinese People’s Liberation Army between July 2014 and December 2016.ParticipantsA total of 180 pairs of patients with gastric cancer and control subjects were recruited in the study, including 134 (74.4%) male pairs and 46 (25.6%) female pairs.Investigation and analysis measuresSerological indicators were tested with ELISA kits. Dietary, lifestyle and psychological factors were investigated through face-to-face questionnaire. Relationships between gastric cancer and these influencing factors were examined by Χ2 test and conditional logistic regression.ResultsSerum PG II and G-17 levels and H. pylori infection rate were higher in patients with gastric cancer than in control subjects (p<0.05), while PG I/II ratio was lower in patients with gastric cancer (p<0.05). Serum G-17 levels were higher in patients with corpus gastric cancer than in patients with antral gastric cancer (p<0.05). Serum PG II levels were higher in patients with advanced gastric cancer than in patients with early-stage cancer (p<0.05), however, PG I/II ratio was lower in patients with advanced-stage gastric cancer than in patients with early-stage cancer (p<0.05). Eating hot food (OR=2.32), eating pickled vegetables (OR=4.05) and often feel troubled (OR=2.21) were found to significantly increase the risk of gastric cancer (all p<0.05), while consuming onion or garlic (OR=0.35), drinking tea (OR=0.26), eating fresh fruits (OR=0.55), and high serum PG I (OR=0.99) or PG I/II ratio (OR=0.73) were found to be protective against gastric cancer.ConclusionStudy results showed that serum PG, G-17 and H. pylori antibodies could be useful indicators for early diagnosis of gastric cancer. Increase in serum G-17 level might indicate the location of gastric cancer. Increase in serum PG II level and decrease in PG I/II ratio might imply the clinical stage. Eating hot food, eating pickled vegetables and often feel troubled may be risk factors for gastric cancer, while eating fresh fruits, eating onion or garlic, and drinking tea may be protective factors against the disease.

Ethnicity and H. Pylori as Risk Factors for Gastric Cancer in Malaysia: A Prospective Case Control Study

2007 ◽  
Vol 102 (1) ◽  
pp. 40-45 ◽  
Author(s):  
Khean-Lee Goh ◽  
Phaik-Leng Cheah ◽  
Noorfaridah Md ◽  
Kia-Fatt Quek ◽  
Navaratnam Parasakthi
Keyword(s):  
Risk Factors ◽  
Gastric Cancer ◽  
Case Control Study ◽  
Case Control ◽  
H Pylori ◽  
Control Study ◽  
Prospective Case Control Study

scholarly journals Risk factors associated with the development of gastric cancer — case-control study

2018 ◽  
Vol 64 (7) ◽  
pp. 611-619 ◽  
Author(s):  
Marcus Fernando Kodama Pertille Ramos ◽  
Ulysses Ribeiro Júnior ◽  
Juliana Kodaira Yukari Viscondi ◽  
Bruno Zilberstein ◽  
Ivan Cecconello ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastric Cancer ◽  
Case Control Study ◽  
Case Control ◽  
Cancer Case ◽  
Gastric Cancer Case ◽  
Factors Associated ◽  
Control Study ◽  
Development Of Gastric Cancer

Risk factors for the gastric cancer: A case–control study in Tibet

2009 ◽  
Vol 41 (1) ◽  
pp. 78-79 ◽  
Author(s):  
K. Li ◽  
Y.L. Zhang ◽  
Z. Dan ◽  
C.M. Zhaxi ◽  
J. Nie
Keyword(s):  
Risk Factors ◽  
Gastric Cancer ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

scholarly journals Difficulty of predicting the presence of lymph node metastases in patients with clinical early stage gastric cancer: a case control study

BMC Cancer ◽  
2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Masatoshi Nakagawa ◽  
Yoon Young Choi ◽  
Ji Yeong An ◽  
Hyunsoo Chung ◽  
Sang Hyuk Seo ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Lymph Node ◽  
Lymph Node Metastases ◽  
Case Control Study ◽  
Early Stage ◽  
Case Control ◽  
Node Metastases ◽  
Control Study

scholarly journals Gastric Cancer and the Daily Intake of the Major Dish Groups Contributing to Sodium Intake: A Case-Control Study in Korea

Nutrients ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 1365
Author(s):  
Jung-Hyun Kwak ◽  
Chang-Soo Eun ◽  
Dong-Soo Han ◽  
Yong-Sung Kim ◽  
Kyu-Sang Song ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Case Control Study ◽  
Sodium Intake ◽  
Daily Intake ◽  
Case Control ◽  
Behavioral Risk ◽  
High Sodium ◽  
Pickled Vegetables ◽  
Control Study ◽  
Current Alcohol

Studies on the association between gastric cancer (GC) and the intake of soup-based dish groups (noodles and dumplings, soups, and stews), which are sodium-contributing foods, in Korea are insufficient, and the results of studies on the intake of pickled vegetables such as kimchi are inconsistent. This study aimed to determine the association between the incidence of GC and the daily intake of high-sodium dish groups (noodles and dumplings, soups, stews, and pickled vegetables) and whether these associations differ depending on behavioral risk factors for GC. In this case-control study, subjects aged 20–79 years were recruited from two hospitals between December 2002 and September 2006. A total of 440 cases and 485 controls were recruited, of which 307 pairs were matched and included for the analysis. In our results, a higher intake of noodles and dumplings was associated with a significantly increased incidence of GC. In the participants who consumed past or current alcohol, a higher intake of noodles and dumplings was associated with a significantly increased incidence of GC. Our results suggest that efforts to reduce the daily sodium intake from noodles and dumplings are needed to prevent and reduce the incidence of GC.

scholarly journals Genitourinary Procedures as Risk Factors for Prosthetic Hip or Knee Infection: A Hospital-Based Prospective Case-Control Study

2015 ◽  
Vol 2 (3) ◽  
Author(s):  
Arjun Gupta ◽  
Douglas R. Osmon ◽  
Arlen D. Hanssen ◽  
Deborah J. Lightner ◽  
Walter R. Wilson ◽  
...  
Keyword(s):  
Risk Factors ◽  
Antibiotic Prophylaxis ◽  
Case Control Study ◽  
Joint Infection ◽  
Case Control ◽  
Total Hip ◽  
Control Subjects ◽  
Increased Risk ◽  
The Impact ◽  
Control Study

Abstract Background.  The purpose of this study was to determine the risk of prosthetic joint infection (PJI) as a complication of routine genitourinary (GU) procedures in patients with total hip arthroplasty (THA) or total knee arthroplasty (TKA) and to study the impact of antibiotic prophylaxis administered prior to these procedures. Methods.  We conducted a prospective, single-center, case-control study between December 1, 2001 and May 31, 2006. Case patients were hospitalized with total hip or knee PJI. Control subjects underwent a THA or TKA and were hospitalized during the same period on the same orthopedic floor without a PJI. Data regarding demographic features and potential risk factors were collected. The outcome measure was the odds ratio (OR) of PJI after GU procedures performed within 2 years of admission. Results.  A total of 339 case patients and 339 control subjects were enrolled in the study. Of these, 52 cases (15%) and 55 controls (16%) had undergone a GU procedure in the preceding 2 years. There was no increased risk of PJI for patients undergoing a GU procedure with or without antibiotic prophylaxis (adjusted OR [aOR] = 1.0, 95% confidence interval [CI] = 0.2–4.5, P = .95 and aOR = 1.0, 95% CI = 0.6–1.7, P = .99, respectively). Results were similar in a subset of patients with a joint age less than 6 months, less than 1 year, or greater than 1 year. Conclusions.  Genitourinary procedures were not risk factors for subsequent PJI. The use of antibiotic prophylaxis before GU procedures did not decrease the risk of subsequent PJI in our study.

scholarly journals Dietary Carotenoids Intake and the Risk of Gastric Cancer: A Case—Control Study in Korea

Nutrients ◽  
2018 ◽  
Vol 10 (8) ◽  
pp. 1031 ◽  
Author(s):  
Ji Hyun Kim ◽  
Jeonghee Lee ◽  
Il Ju Choi ◽  
Young-Il Kim ◽  
Oran Kwon ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Fruits And Vegetables ◽  
Case Control Study ◽  
Case Control ◽  
Cancer Center ◽  
Inverse Association ◽  
Tomato Ketchup ◽  
Center Hospital ◽  
H Pylori ◽  
Control Study

Although the incidence of gastric cancer (GC) has declined, it remains the second most common cancer in Korea. As a class of phytochemicals, carotenoids are fat-soluble pigments that are abundant in fruits and vegetables and have health-promoting properties, including cancer prevention effects. This case-control study investigated the effects of total dietary carotenoids, dietary carotenoid subclasses (α-carotene, β-carotene, β-cryptoxanthin, lutein/zeaxanthin, and lycopene), and foods contributing to the dietary intake of each carotenoid on the risk of GC. Four hundred and fifteen cases and 830 controls were recruited from the National Cancer Center Hospital in Korea between March 2011 and December 2014. A significant inverse association between total dietary carotenoids and GC risk was observed among women (odds ratio (OR) 0.56, 95% confidence interval (CI) 0.32–0.99). A higher intake of dietary lycopene was inversely associated with GC risk overall in the subjects (OR 0.60, 95% CI 0.42–0.85, p for trend = 0.012), men (OR 0.60, 95% CI 0.39–0.93), and women (OR 0.54, 95% CI 0.30–0.96, p for trend = 0.039). This significant association between dietary lycopene intake and GC risk was also observed in the subgroups of Helicobacter pylori (H. pylori)-positive subjects and those who had ever smoked. Among the major contributing foods of dietary lycopene, consumption of tomatoes and tomato ketchup was inversely associated with GC risk in the overall subjects, men, and women. Based on our findings, a higher intake of dietary lycopene and contributing foods of lycopene (tomatoes and tomato ketchup) may be inversely associated with the risk of GC.

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