scholarly journals Net survival differences of breast cancer between stages at diagnosis and age groups in the east coast region of West Malaysia: a retrospective cohort study

BMJ Open ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. e043642
Author(s):  
Tengku Muhammad Hanis ◽  
Najib Majdi Yaacob ◽  
Suhaily Mohd Hairon ◽  
Sarimah Abdullah

ObjectiveEstimation of the net survival of breast cancer helps in assessing breast cancer burden at a population level. Thus, this study aims to estimate the net survival of breast cancer at different cancer staging and age at diagnosis in the east coast region of West Malaysia.SettingKelantan, Malaysia.ParticipantsAll breast cancer cases diagnosed in 2007 and 2011 identified from Kelantan Cancer Registry.DesignThis retrospective cohort study used a relative survival approach to estimate the net survival of patients with breast cancer. Thus, two data were needed; breast cancer data from Kelantan Cancer Registry and general population mortality data for Kelantan population.Primary and secondary outcome measuresNet survival according to stage and age group at diagnosis at 1, 3 and 5 years following diagnosis.ResultsThe highest net survival was observed among stage I and II breast cancer cases, while the lowest net survival was observed among stage IV breast cancer cases. In term of age at diagnosis, breast cancer cases aged 65 and older had the best net survival compared with the other age groups.ConclusionThe age at diagnosis had a minimal impact on the net survival compared with the stage at diagnosis. The finding of this study is applicable to other populations with similar breast cancer profile.

2009 ◽  
Vol 100 (8) ◽  
pp. 1479-1484 ◽  
Author(s):  
Masaaki Kawai ◽  
Shinichi Kuriyama ◽  
Akihiko Suzuki ◽  
Yoshikazu Nishino ◽  
Takanori Ishida ◽  
...  

The Lancet ◽  
2003 ◽  
Vol 361 (9352) ◽  
pp. 125-129 ◽  
Author(s):  
David L Page ◽  
Peggy A Schuyler ◽  
William D Dupont ◽  
Roy A Jensen ◽  
W Dale Plummer ◽  
...  

BDJ Open ◽  
2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Deborah Moore ◽  
Thomas Allen ◽  
Stephen Birch ◽  
Martin Tickle ◽  
Tanya Walsh ◽  
...  

Abstract Background Tooth decay can cause pain, sleepless nights and loss of productive workdays. Fluoridation of drinking water was identified in the 1940s as a cost-effective method of prevention. In the mid-1970s, fluoride toothpastes became widely available. Since then, in high-income countries the prevalence of tooth decay in children has reduced whilst natural tooth retention in older age groups has increased. Most water fluoridation research was carried out before these dramatic changes in fluoride availability and oral health. Furthermore, there is a paucity of evidence in adults. The aim of this study is to assess the clinical and cost-effectiveness of water fluoridation in preventing invasive dental treatment in adults and adolescents aged over 12. Methods/design Retrospective cohort study using 10 years of routinely available dental treatment data. Individuals exposed to water fluoridation will be identified by sampled water fluoride concentration linked to place of residence. Outcomes will be based on the number of invasive dental treatments received per participant (fillings, extractions, root canal treatments). A generalised linear model with clustering by local authority area will be used for analysis. The model will include area level propensity scores and individual-level covariates. The economic evaluation will focus on (1) cost-effectiveness as assessed by the water fluoridation mean cost per invasive treatment avoided and (2) a return on investment from the public sector perspective, capturing the change in cost of dental service utilisation resulting from investment in water fluoridation. Discussions There is a well-recognised need for contemporary evidence regarding the effectiveness and cost-effectiveness of water fluoridation, particularly for adults. The absence of such evidence for all age groups may lead to an underestimation of the potential benefits of a population-wide, rather than targeted, fluoride delivery programme. This study will utilise a pragmatic design to address the information needs of policy makers in a timely manner.


2021 ◽  
Vol 63 ◽  
pp. 102144
Author(s):  
Sumadi Lukman Anwar ◽  
Roby Cahyono ◽  
Widya Surya Avanti ◽  
Heru Yudhanto Budiman ◽  
Wirsma Arif Harahap ◽  
...  

The Breast ◽  
2017 ◽  
Vol 32 ◽  
pp. 102-104 ◽  
Author(s):  
Navid Mohamadpour Toyserkani ◽  
Mads Gustaf Jørgensen ◽  
Karen Haugaard ◽  
Jens Ahm Sørensen

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