Abstract
Background: Some previous studies have suggested that elevated TG/HDL ratio is a risk factor for the development of insulin resistance.There is also evidence that TG/HDL ratios are ethnically diverse.Currently, there is still insufficient evidence on whether TG/HDL is a risk factor for the occurrence of insulin resistance in the US population. Therefore, we attempted to find out whether TG/HDL represents a risk factor for the occurrence of insulin resistance in the US population by studying the NHANES database (2017-2108).Methods: After adjusting the potential influencing factors, we used the method of multiple logistic regression to analyze the risk between TG/HDL and insulin resistance, and determined whether there was a linear relationship between TG/HDL and insulin resistance by smoothing curve fitting.At the same time, in order to verify the reliability of the results, we conducted a subgroup analysis.Results: We found that in the American population, increased TG/HDL ratio was a risk factor for insulin resistance (OR=2.47 (2.01,3.04)).At the same time, we found a saturation effect between TG/HDL ratio and insulin resistance.When the ratio was <0.84, the relationship between TG/HDL and the occurrence of insulin resistance was very significant (OR=21.24 (9.29,48.56)), and when the ratio was ≥0.84, the effect value was relatively reduced (OR=1.45(1.10,1.92)).Conclusions:In this study, we found that TG/HDL is negatively correlated with insulin resistance in the American population (except Hispanic Americans), and this effect is especially significant in people with higher education.
P67 The associations of serum 25-hydroxy-vitamin D and ionised calcium with lung function and allergen skin prick tests in adolescents and adults: findings from a cross-sectional study using the US Third National Health and Nutrition Examination Survey (NHANES III)
