Anti-plague vaccine: Its effects on the normal individual

1918 ◽  
Vol 4 (2) ◽  
pp. 212.1-212
Author(s):  
R. H Mcgiffin
Keyword(s):  
Normal Individual ◽  
Plague Vaccine

Influence of Freeze-Drying Modes on the Quality of Live Plague Vaccine

2019 ◽  
Vol 35 (4) ◽  
pp. 73-78
Author(s):  
S.E. Gostischeva ◽  
D.V. Rostovtseva ◽  
G.F. Ivanova ◽  
A.V. Kostrominov ◽  
M.V. Pilipenko
Keyword(s):  
Heating Rate ◽  
Freeze Drying ◽  
Eutectic Point ◽  
Freezing Temperature ◽  
Freezing Time ◽  
Residual Moisture ◽  
High Viability ◽  
Plague Vaccine ◽  
Selection Of

The optimization of the drying schedule has been carried out to improve the quality indicators of the live plague vaccine. Based on the data obtained on the eutectic point of the vaccine suspension, the freezing temperature and freezing time were set to -50 °С and 6-7 h, respectively. A pressure of 40 mTorr over the surface of the drying suspension and 20 mTorr during the desorption were shown to be the best conditions for sublimation. The drying tests with different options for the shelf heating rate, vacuum depth and duration of intermediate temperature indicators were carried out to develop the improved freeze-drying mode providing the selection of the most adapted bacteria. A vaccine lyophilized under the developed conditions has low residual moisture (up to 2%) and high viability index that persists over the whole shelf life. lyophilization, sublimation, eutectic, live plague vaccine, residual moisture, viability

THE ADMINISTRATION OF PLAGUE VACCINE

BMJ ◽  
1924 ◽  
Vol 2 (3315) ◽  
pp. 83-83
Author(s):  
R. Mansoor
Keyword(s):  
Plague Vaccine

The value of X rays as a research method in medicine

1908 ◽  
Vol 8 (1-2) ◽  
pp. 1-17
Author(s):  
M. Chalusov
Keyword(s):  
Research Method ◽  
Normal Individual ◽  
Individual Case ◽  
Human Organism ◽  
Wide Sense ◽  
X Rays ◽  
Normal Human ◽  
Clear Idea

The task of our science of medicine, to put it briefly, is to heal the suffering man; but this simple and briefly expressed task is extremely difficult, extremely responsible, and the possibility of its fulfillment is achievable only with the satisfaction of certain well-known requirements. Among these requirements, it is necessary to mention the desire to establish an understanding of the average normal human organism, a clear idea of ​​normal individual deviations, the study of conditions that are conducive not only to the preservation, but also to the prosperity of these two types of life in the study of the wide sense of the causes of this organism; hence the need to establish an understanding of "diseases", their types, signs, reasons in each individual case ...

scholarly journals A Phase I Safety and Immunogenicity Dose Escalation Trial of Plague Vaccine, Flagellin/F1/V, in Healthy Adult Volunteers (DMID 08-0066)

2015 ◽  
Vol 2 (suppl_1) ◽  
Author(s):  
Sharon E Frey ◽  
Kathleen Lottenbach ◽  
Irene Graham ◽  
Edwin Anderson ◽  
Kanwaldeep Bajwa ◽  
...  
Keyword(s):  
Phase I ◽  
Dose Escalation ◽  
Healthy Adult ◽  
Plague Vaccine ◽  
Adult Volunteers

APPARENT FIELD SAFETY OF A RACCOON POXVIRUS-VECTORED PLAGUE VACCINE IN FREE-RANGING PRAIRIE DOGS (CYNOMYS SPP.), COLORADO, USA

2015 ◽  
Vol 51 (2) ◽  
pp. 401-410 ◽  
Author(s):  
Daniel W. Tripp ◽  
Tonie E. Rocke ◽  
Sean P. Streich ◽  
Rachel C. Abbott ◽  
Jorge E. Osorio ◽  
...  
Keyword(s):  
Prairie Dogs ◽  
Free Ranging ◽  
Plague Vaccine

scholarly journals EFFECT OF ALCOHOLISM ON LIVER FUNCTION TEST IN RURAL POPULATION IN INDIA

2020 ◽  
Vol 4 (8) ◽  
Author(s):  
Richa K Lath ◽  
Aniruddha Jibhkate
Keyword(s):  
Liver Function ◽  
Liver Function Test ◽  
Liver Damage ◽  
Total Protein ◽  
Liver Enzymes ◽  
Normal Individual ◽  
Public Health Problem ◽  
Albumin Level ◽  
Study Group ◽  
Function Test

Background: alcoholism is one of the major socioeconomic as well as public health problem in India. The problem is occurring equally in urban as well as in rural India. This study was carried out in essence of liver damage in alcoholics and alteration in the biochemical enzymes in the serum with respect to liver damage. Method: 100 alcoholics and 100 non alcoholic patients were selected from the hospital OPD. Liver function test was performed in both the study group. Liver  enzymes ALT,AST,ALP and the total protein and albumin level were compared in  the study group and controls. Results: The results showed there is significant increase in the liver enzymes ALT,AST,ALP in the alcoholic patients as compared to normal individual and significant fall in concentration of the total protein and albumin level in the alcoholics. Keywords: Alcoholics, liver function test

scholarly journals Proliferative state of blast cell progenitors in acute myeloblastic leukemia (AML)

Blood ◽  
1978 ◽  
Vol 52 (3) ◽  
pp. 592-600 ◽  
Author(s):  
MD Minden ◽  
JE Till ◽  
EA McCulloch
Keyword(s):  
T Lymphocyte ◽  
High Frequency ◽  
Proliferative Activity ◽  
Normal Individual ◽  
S Phase ◽  
Blast Cell ◽  
Acute Myeloblastic Leukemia ◽  
Low Concentrations ◽  
Blast Cells ◽  
Small Subpopulation

Abstract Peripheral blood from patients with acute myeloblastic leukemia (AML) contains cells capable of giving rise to colonies in culture when stimulated by media conditioned by leukocytes (LCM) in the presence of phytohemagglutinin (PHA). Two types of colonies are recognized with high frequency: The first grows in the presence of low concentrations of PHA LCM, have a blast-like morphology, and are numerically correlated with morphologically identified blast cells. The second requires either high PHA LCM concentrations or PHA alone with or without 2-mercaptoethanol and consists of cells capable of forming rossettes with sheep erythrocytes and resembles. T-lymphocyte colonies from normal blood. Precursors of blast cell colonies from 15 leukemic patients were tested for cycle state, using either the 3H-thymidine or hydroxyurea techniques. All were found to have a high proportion of cells in the S phase of the cycle. In contrast, T lymphocyte precursors from three normal individual were quiescent. The data are consistent with the maintenance of the leukemic blast cell populations by the proliferative activity of a small subpopulation of blasts.

PLAGUE VACCINE

The Lancet ◽  
1946 ◽  
Vol 248 (6422) ◽  
pp. 462
Keyword(s):  
Plague Vaccine
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