The added value of peripheral blood cell morphology in the diagnosis and management of infectious diseases--part 2: illustrative cases

2008 ◽  
Vol 84 (997) ◽  
pp. 586-589 ◽  
Author(s):  
I Potasman ◽  
M Prokocimer
Keyword(s):  
Infectious Diseases ◽  
Blood Cell ◽  
Cell Morphology ◽  
Peripheral Blood ◽  
Peripheral Blood Cell ◽  
Added Value ◽  
Diagnosis And Management ◽  
Blood Cell Morphology

Recommendation for the Peripheral Blood Cell Morphology Report

2019 ◽  
Vol 9 (3) ◽  
pp. 115
Author(s):  
Jung Ah Kwon ◽  
Young-gon Kim ◽  
Geon Park ◽  
Ji-myung Kim ◽  
Young-Uk Cho ◽  
...  
Keyword(s):  
Blood Cell ◽  
Cell Morphology ◽  
Peripheral Blood ◽  
Peripheral Blood Cell ◽  
Blood Cell Morphology

scholarly journals Detection of Intracellular Parasites by Use of the CellaVision DM96 Analyzer during Routine Screening of Peripheral Blood Smears

2014 ◽  
Vol 53 (1) ◽  
pp. 167-171 ◽  
Author(s):  
Lori D. Racsa ◽  
Rita M. Gander ◽  
Paul M. Southern ◽  
Erin McElvania TeKippe ◽  
Christopher Doern ◽  
...  
Keyword(s):  
Blood Cell ◽  
Cell Morphology ◽  
Red Blood Cell ◽  
Peripheral Blood ◽  
Detection Rate ◽  
Detection Rates ◽  
Content Type ◽  
Blood Smears ◽  
Blood Cell Morphology ◽  
Peripheral Blood Smears

Conventional microscopy is the gold standard for malaria diagnosis. The CellaVision DM96 is a digital hematology analyzer that utilizes neural networks to locate, digitize, and preclassify leukocytes and characterize red blood cell morphology. This study compared the detection rates ofPlasmodiumandBabesiaspecies on peripheral blood smears utilizing the CellaVision DM96 with the rates for a routine red blood cell morphology scan. A total of 281 slides were analyzed, consisting of 130 slides positive forPlasmodiumorBabesiaspecies and 151 negative controls. Slides were blinded, randomized, and analyzed by CellaVision and microscopy for red cell morphology scans. The technologists were blinded to prior identification results. The parasite detection rate was 73% (95/130) for CellaVision and 81% (105/130) for microscopy for positive samples. The interobserver agreement between CellaVision and microscopy was fair, as Cohen's kappa coefficient equaled 0.36. Pathologist review of CellaVision images identified an additional 15 slides with parasites, bringing the total number of detectable positive slides to 110 of 130 (85%).Plasmodium ovalehad the lowest rate of detection at 56% (5 of 9);Plasmodium malariaeandBabesiaspp. had the highest rate of detection at 100% (3/3 and 6/6, respectively). The detection rate by CellaVision was 100% (23/23) when the parasitemia was ≥2.5%. The detection rate for <0.1% parasitemia was 63% (15/24). Technologists appropriately classified all negative specimens. The percentage of positive specimens detectable by CellaVision (73%) approaches results for microscopy on routine scan of peripheral blood smears for red blood cell morphology.

Evaluation of a Flow-Cytometric Osmotic Fragility Test for Hereditary Spherocytosis in Chinese Patients

2015 ◽  
Vol 135 (2) ◽  
pp. 88-93 ◽  
Author(s):  
Yi-Feng Tao ◽  
Zeng-Fu Deng ◽  
Lin Liao ◽  
Yu-Ling Qiu ◽  
Xue-Lian Deng ◽  
...  
Keyword(s):  
Blood Cell ◽  
Red Blood Cells ◽  
Cell Morphology ◽  
Red Blood Cell ◽  
Peripheral Blood ◽  
Blood Cells ◽  
Hereditary Spherocytosis ◽  
Osmotic Fragility ◽  
Flow Cytometric ◽  
Blood Cell Morphology

Background: Osmotic fragility testing based on flow cytometry was recently introduced for the screening of hereditary spherocytosis (HS). This study was undertaken to evaluate the clinical diagnostic value of a flow-cytometric osmotic fragility test for HS. Methods: Peripheral blood was collected from 237 subjects at the First Affiliated Hospital of Guangxi Medical University, including 56 HS patients, 86 thalassemia patients and 95 healthy controls. The samples were examined by flow-cytometric osmotic fragility test and the percentage of residual red blood cells was used to determine HS. Peripheral blood smears were performed to examine the red blood cell morphology. Results: With clinical diagnosis of HS as the gold standard and the percentage of residual red blood cells <23.6% as the diagnostic threshold in the flow-cytometric osmotic fragility test, the sensitivity of the flow-cytometric osmotic fragility test for HS was 85.71% and the specificity was 97.24%. Conclusion: The flow-cytometric osmotic fragility test combined with a red blood cell morphology test by peripheral blood smear could be a simple, practical and accurate laboratory screening method for HS.

scholarly journals RED BLOOD CELL MORPHOLOGY: STILL AN IMPORTANT TOOL FOR ANEMIA TYPING

2018 ◽  
Vol 6 (3) ◽  
pp. 298-301
Author(s):  
Ekta Patidar
Keyword(s):  
Blood Cell ◽  
Physical Examination ◽  
Cell Morphology ◽  
Red Blood Cell ◽  
Peripheral Blood ◽  
Clinical History ◽  
Blood Examination ◽  
Diagnostic Interpretation ◽  
Blood Cell Morphology ◽  
Laboratory Investigations

Anemia is a common entity which every clinician and pathologist faces very frequently. Proper clinical history, physical examination and laboratory investigations are essential for diagnostic interpretation of anemia. Peripheral blood examination is a basic screening haematological tool used for its evaluation.

scholarly journals Blood cell morphology and leukocyte differential of Morelet’s crocodile (Crocodylus moreletii) (Crocodylidae)

2021 ◽  
Vol 27 (1) ◽  
Author(s):  
Adrián Gutiérrez-Cervantes ◽  
Concepción del Carmen Ahuja-Aguirre ◽  
Lorena López-deBuen ◽  
Sergio Alberto Viveros-Peredo
Keyword(s):  
Blood Cell ◽  
Cell Morphology ◽  
Peripheral Blood ◽  
Blood Cells ◽  
Morphological Characteristics ◽  
Differential Count ◽  
Adult Males ◽  
Leukocyte Differential Count ◽  
Blood Cell Morphology ◽  
Crocodylus Moreletii

The objective of the study was to determine the morphological characteristics of peripheral blood cells (erythrocytes, leukocytes, thrombocytes) and the leukocyte differential count (heterophils, eosinophils, basophils, lymphocytes, monocytes, azurophils) of captive Morelet’s crocodiles (Crocodylus moreletii) from Veracruz, Mexico. Peripheral blood from 80 apparently healthy farmed crocodiles (39 subadults [19 females, 20 males] and 41 adults [18 females, 23 males]) was examined for morphology through stained blood smears and manual count was used for the leukocyte differential. Blood was collected during the non-breeding (n = 42) and breeding (n = 38) seasons. Blood examination indicated similar morphological characteristics of blood cells in subadult and adult individuals and in females and males in both seasons. Erythrocytes were the largest blood cells and lymphocytes the smallest. The leukocyte differential count showed that lymphocytes were the most abundant leukocytes and basophils the least numerous. The percentages of some leukocytes showed difference by season (non-breeding and breeding) in subadult and adult males (p < 0.05) and by size (subadults and adults) in males and females but only in the non-breeding season (p < 0.05). The leukocytes that showed the greatest variation were lymphocytes, heterophils and eosinophils. The knowledge of blood cell morphology and the leukocyte differential count in healthy farmed Morelet’s crocodiles will allow the accurate diagnosis of some diseases of captive and wild individuals.  

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