Chemistry of the aminochromes. Part XI. Studies on 2-methylaminochromes
Keyword(s):
2-Methyladrenochrome and 1-ethyl-2-methylnoradrenochrome have been prepared by oxidation of 3,4-dihydroxyephedrine and 3,4-dihydroxyhomoephedrine with silver oxide. The corresponding 7-iodoaminochromes were obtained when the oxidations were carried out with potassium iodate. The expected 3,5,6-triacetoxyindoles were formed by treatment of these aminochromes with acetic anhydride and pyridine and the corresponding 5,6-dihydroxyindoles (isolated as their diacetyl derivatives) were obtained by reduction of the aminochromes with sodium borohydride or sodium hydrosulfite. An improved procedure for the synthesis of 3,4-dihydroxyephedrine (α-methyladrenaline) is also described.
2021 ◽
Vol ahead-of-print
(ahead-of-print)
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Keyword(s):
1969 ◽
Vol 47
(21)
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pp. 4091-4093
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Keyword(s):
Keyword(s):
2005 ◽
Vol 70
(4)
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pp. 479-486
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1968 ◽
Vol 23
(11)
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pp. 1430-1443
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1975 ◽
Vol 33
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pp. 318-319