DIFFERENTIAL ABSORPTION OF PLANT STEROLS IN THE DOG

1962 ◽  
Vol 40 (1) ◽  
pp. 1493-1504 ◽  
Author(s):  
A. Kuksis ◽  
T. C. Huang

Eight adult female dogs (8 to 10 kg) with thoracic duct fistula were fed 5 to 10% solutions of mixed plant sterols in oleic acid, corn oil, or butter. The lymph, which flowed at a rate of 20 to 50 ml per hour, was drained for 18 to 26 hours. Each 2-hour collection was analyzed separately for cholesterol and plant sterols. Under comparable conditions and following a single meal containing plant sterol, about 35 mg of this sterol was transferred to lymph in 24 hours when corn oil was fed and 130 mg in the case of butterfat. At the time of maximum sterol absorption (8 to 12 hours after feeding) as much as 15% of the total lymph sterol was contributed by the plant sterols. Significant absorption of both β- and γ-sitosterol was observed, the γ-isomer being assimilated some 4 to 5 times as readily as the β-isomer. About 50% of the total lymph cholesterol was esterified. Essentially all of the absorbed plant sterol was free.

1962 ◽  
Vol 40 (11) ◽  
pp. 1493-1504 ◽  
Author(s):  
A. Kuksis ◽  
T. C. Huang

Eight adult female dogs (8 to 10 kg) with thoracic duct fistula were fed 5 to 10% solutions of mixed plant sterols in oleic acid, corn oil, or butter. The lymph, which flowed at a rate of 20 to 50 ml per hour, was drained for 18 to 26 hours. Each 2-hour collection was analyzed separately for cholesterol and plant sterols. Under comparable conditions and following a single meal containing plant sterol, about 35 mg of this sterol was transferred to lymph in 24 hours when corn oil was fed and 130 mg in the case of butterfat. At the time of maximum sterol absorption (8 to 12 hours after feeding) as much as 15% of the total lymph sterol was contributed by the plant sterols. Significant absorption of both β- and γ-sitosterol was observed, the γ-isomer being assimilated some 4 to 5 times as readily as the β-isomer. About 50% of the total lymph cholesterol was esterified. Essentially all of the absorbed plant sterol was free.


2001 ◽  
Vol 131 (7) ◽  
pp. 1942-1945 ◽  
Author(s):  
Anne Tammi ◽  
Tapani Rönnemaa ◽  
Liisa Valsta ◽  
Ritva Seppänen ◽  
Leena Rask-Nissilä ◽  
...  

2016 ◽  
Vol 7 (1) ◽  
pp. 110-117 ◽  
Author(s):  
Silvia Vaghini ◽  
Antonio Cilla ◽  
Guadalupe Garcia-Llatas ◽  
María Jesús Lagarda

The bioaccessibility (BA) of total and individual plant sterols (PS) of four commercial PS-enriched fermented milk beverages (designated as A to D) was evaluated using in vitro gastrointestinal digestion including the formation of mixed micelles.


Author(s):  
Carrillo W ◽  
Carpio C ◽  
Morales D ◽  
Vilcacundo E ◽  
Álvarez M ◽  
...  

  Objective: The aim of this work was to determine the fatty acids content in corn seeds oil (Zea mays) sample cultivated in Ecuador.Methods: Corn oil was obtained from corn oil seeds using the cold pressing method. Methyl esters fatty acids analysis were carried out using the gas chromatography (GC) method with a mass selective detector and using the database library NIST 14.L to identify the compounds present in the corn seed oil.Results: Methyl esters fatty acids were identified from corn (Z. mays) seeds using the GC mass spectrometer (GC-MS) analytical method. Fatty acids were analyzed as methyl esters on a capillary column DB-WAX 122-7062 with a good separation of palmitic acid, stearic acid, oleic acid, elaidic acid, linoleic acid, arachidic acid, and linolenic acid. The structure of methyl esters fatty acids was determined using the GS-MS method. Corn oil has a high content of linoleic acid (omega 6) with a value of 52.68% of the total content of fatty acids in corn oil and 29.70% of oleic acid (omega 9) of the total content of fatty acids in corn oil. The sample presented a value of 12.57% of palmitic acid.Conclusions: Corn oil shows a good content of fatty acids omega 6 and 9. The higher value was of omega 6 with 52.68% content. Corn oil has a good proportion of polyunsaturated of lipids (53.80%) and 14.86% of saturated lipids.


2002 ◽  
Vol 47 (3) ◽  
pp. 416-420 ◽  
Author(s):  
Cintia B. Gonçalves ◽  
Eduardo Batista ◽  
Antonio J. A. Meirelles

Author(s):  
Helena Gylling ◽  
Tatu A Miettinen

Phytosterols are plant sterols, mainly campesterol and sitosterol, and their respective stanols (5α-saturated derivatives), which chemically resemble cholesterol. They are present in a normal diet and are absorbed proportionally to cholesterol, but to a much lesser extent, such that less than 0.1% of serum sterols are plant sterols. Phytosterols inhibit intestinal cholesterol absorption, and fat-soluble plant stanol esters were introduced as a functional food for lowering serum cholesterol in the early 1990s; plant sterol esters entered the market at the end of the 1990s. Inhibition of the intestinal absorption of cholesterol stimulates cholesterol synthesis, a factor which limits serum cholesterol lowering to about 10% with phytosterols. Enrichment of the diet with plant stanol esters reduces absorption and serum concentrations of both cholesterol and plant sterols, whereas enrichment of the diet with plant sterol esters, especially in combination with statins, lowers serum cholesterol but increases serum plant sterol levels. Recent studies have suggested that high-serum plant sterol levels may be associated with increased coincidence of coronary heart disease. Estimates of coronary heart disease reduction by 20-25% with plant sterols/stanols is based mainly on short-term studies. Long-term cholesterol lowering, needed for the prevention of coronary heart disease, may be successful with plant stanol esters, which lower serum cholesterol in both genders over at least a year.


1961 ◽  
Vol 39 (2) ◽  
pp. 195-201 ◽  
Author(s):  
Joyce L. Beare ◽  
E. R. W. Gregory ◽  
D. Morison Smith ◽  
J. A. Campbell

Rats fed corn oil or a mixture of lard and olive oil produced as many offspring as those receiving no fat supplement with a low-fat commercial meal, but the weanling weight was lower. Although rats fed rapeseed oil continued to reproduce they had fewer and smaller offspring than rats fed other diets.The composition of fatty acids in the milk varied with the dietary fat of the mother. Animals receiving the low-fat diet secreted predominantly saturated fatty acids. A high proportion of linoleic acid appeared in the milk when corn oil was fed, and of oleic acid when the mixture of lard and olive oil was fed. Eicosenoic and erucic acids were present in the milk of rats receiving rapeseed oil, but were less prevalent than in the original oil.


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