Gender effects of tall oil versus soybean phytosterols as cholesterol-lowering agents in hamsters

1998 ◽  
Vol 76 (7-8) ◽  
pp. 780-787 ◽  
Author(s):  
Fady Y Ntanios ◽  
Diane E MacDougall ◽  
Peter JH Jones
Keyword(s):  
Total Cholesterol ◽  
Cholesterol Level ◽  
Cholesterol Metabolism ◽  
Total Cholesterol Level ◽  
Cholesterol Biosynthesis ◽  
Gender Effects ◽  
Plasma Total Cholesterol ◽  
Tall Oil ◽  
Cholesterol Lowering ◽  
Plasma Total Cholesterol Level

To examine the effect of gender on the mechanisms of action of phytosterols extracted from tall oil (TO) and soybean (SB) on cholesterol and phytosterol metabolism, male and female hamsters were fed cholesterol-enriched diets containing 0.5 or 1% (w/w) TO or SB phytosterols for 90 days. Plasma lipoprotein cholesterol profile and tissue phytosterol and cholesterol biosynthesis levels were determined. Mean plasma total-cholesterol level in females fed 1% (w/w) SB was reduced (p < 0.05) by 44%, while in males it was lowered (p < 0.05) by 25% compared with their respective controls. Moreover, mean plasma total-cholesterol level was reduced (p < 0.05) in male hamsters by -31% and female hamsters by -32% when fed 1% (w/w) TO. Cholesterol biosynthesis was higher (p < 0.05) by twofold in groups fed TO at 0.5 and 1% (w/w) concentrations, compared with SB. Hamsters fed TO at 0.5 and 1% (w/w) levels also had higher (p < 0.05) hepatic and enterocytic campesterol contents than SB-fed animals. These findings demonstrate gender differences in cholesterol metabolism in TO- and SB-fed hamsters. The results suggest that TO, conversely to SB phytosterol, is a more effective cholesterol-lowering agent in male, but not as much in female, hamsters, over a feeding period of 90 days.Key words: phytosterols, cholesterol, sitosterol, sitostanol, gender, hamster.

scholarly journals Plasma total cholesterol level and some related factors in northern Iranian people

2013 ◽  
Vol 4 (2) ◽  
pp. 359 ◽  
Author(s):  
Gholamreza Veghari ◽  
Mehdi Sedaghat ◽  
Hamidraza Joshghani ◽  
Farhad Niknezad ◽  
Abdolhamid Angizeh ◽  
...  
Keyword(s):  
Total Cholesterol ◽  
Cholesterol Level ◽  
Total Cholesterol Level ◽  
Plasma Total Cholesterol ◽  
Related Factors ◽  
Plasma Total Cholesterol Level

scholarly journals Relationship Between Plasma Total Cholesterol Level and Ovarian Response in Superovulated Japanese Black Cows

1987 ◽  
Vol 58 (8) ◽  
pp. 711-713
Author(s):  
Yoshiyuki MARUO ◽  
Tutomu SAWADA ◽  
Toshio INABA ◽  
Kazuyuki KONISHI ◽  
Norio SAITO ◽  
...  
Keyword(s):  
Total Cholesterol ◽  
Cholesterol Level ◽  
Total Cholesterol Level ◽  
Ovarian Response ◽  
Plasma Total Cholesterol ◽  
Plasma Total Cholesterol Level

scholarly journals Plasma Total Cholesterol Level as a Risk Factor for Alzheimer Disease

2003 ◽  
Vol 163 (9) ◽  
pp. 1053 ◽  
Author(s):  
Zaldy Sy Tan ◽  
Sudha Seshadri ◽  
Alexa Beiser ◽  
Peter W. F. Wilson ◽  
Douglas P. Kiel ◽  
...  
Keyword(s):  
Risk Factor ◽  
Alzheimer Disease ◽  
Total Cholesterol ◽  
Cholesterol Level ◽  
Total Cholesterol Level ◽  
Plasma Total Cholesterol ◽  
Plasma Total Cholesterol Level

scholarly journals PENGARUH PEMBERIAN KEFIR SUSU SAPI TERHADAP KADAR KOLESTEROL TOTAL TIKUS JANTAN SPRAGUE DAWLEY

2012 ◽  
Vol 1 (1) ◽  
pp. 224-228
Author(s):  
Finta Wahdania ◽  
Adriyan Pramono
Keyword(s):  
Total Cholesterol ◽  
Cholesterol Level ◽  
Serum Cholesterol ◽  
Serum Cholesterol Level ◽  
Total Cholesterol Level ◽  
Control Group ◽  
High Cholesterol Diet ◽  
Sprague Dawley ◽  
Control Group Design ◽  
Cholesterol Lowering

Background : A high serum cholesterol level might become one of contributing risk factor for development of cardiovascular disease (CVD). Serum cholesterol level could decreased by acid lactic bacteria (ALB) content. Kefir, one of probiotic product have been claimed as a cholesterol-lowering agent. The purpose of this research was to determine effect of cwo milk kefir to serum total cholesterol level in animal model. Method : true-experimental by using pre post test with randomized control group design. Twenty eight male Sprague dawley rat were divided into four group (K,P1, P2, P3) and induced by high cholesterol diet. Intervention started from 1,5 ml; 2 ml and 3 ml of kefir respectively to P1, P2 and P3 for fifteen days. Cholesterol level was examined by CHOD-PAP method. Data was examined by using one way ANOVA. Result : Total cholesterol level decreased significantly in all group but there is no defference between group. The highest reduction of total cholesterol was 31,45%, found in group P3 followed by 31,40% for K; 30,90% for P2 and 27,04 % for P1. Conclusion : kefir administration did not contribute in lowered total cholesterol level, result of this study did not support administration of kefir as a cholesterol-lowering agent

Pengaruh Pemberian Terapi Oksigen Hiperbarik Terhadap Kadar Kolesterol Total Pada Tikus Putih (Rattus novergicus) Jantan Galur Wistar Yang Di Induksi Diet Tinggi Lemak

2018 ◽  
Vol 16 (1) ◽  
pp. 1 ◽  
Author(s):  
AZRUL HILDAN SAFRIZAL
Keyword(s):  
Cardiovascular Disease ◽  
Total Cholesterol ◽  
Cholesterol Level ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
High Fat Diet ◽  
Oxygen Therapy ◽  
Total Cholesterol Level ◽  
High Fat ◽  
Cholesterol Levels

<p>The pattern and lifestyle of today's society with the presence of an interner facility makes people spend more time sitting out than on exercise and increased consumption of high-fat foods may increase the risk of cardiovascular disease. An effective therapy is needed in preventing the occurrence of cardiovascular disease. Hyperbaric oxygen now starts to develop for the treatment of several diseases, which in turn can increase the gene forming antioxidant enzymes and ROS. To determine effect of hyperbaric oxygen therapy on total cholesterol levels of wistar white rats (Rattusnovergicus) induced bye high fat. The study was carried out in an expeative post test only group control of three groups. One group is given standard feed. All groups induced high-fat diet and standard feed. Of the two groups induced, one group was given hyperbaric oxygen therapy with a dose of 3 x 30 minutes for six days on day 7 at a blood test to determine total cholesterol levels<strong>. </strong>One way Anova parametric statistic test showed that p = 0.007 &lt; α proved hypothesis that hyperbaric oxygen therapy giving effect to total cholesterol level of white mice of jantangalurist rings induced by high fat diet. Total cholesterol was significantly different between K (-) and K (+) and between K (-) and P. It was found that hyperbaric oxygen therapy had an effect on total cholesterol level dose of 3x30 minutes for six days.</p>

Tracking of Serum Cholesterol Levels in a Multiracial Sample of Preschool Children

PEDIATRICS ◽  
1992 ◽  
Vol 90 (1) ◽  
pp. 80-86 ◽  
Author(s):  
David S. Freedman ◽  
Tim Byers ◽  
Karen Sell ◽  
Sarah Kuester ◽  
Eva Newe1l ◽  
...  
Keyword(s):  
Total Cholesterol ◽  
Cholesterol Level ◽  
Initial Level ◽  
Total Cholesterol Level ◽  
Relative Weight ◽  
Cholesterol Levels ◽  
Final Measurement ◽  
Subsequent Measurement ◽  
Initial Measurement

The relation of an initial measurement of serum total cholesterol to subsequent levels over a (mean) 13-month interval was examined in a multiracial (white, Hispanic, American Indian, and black) sample of 1680 one- to four-year-olds. Although the relation of the initial level to the final measurement (r = .54) did not vary by race, sex, relative weight, or changes in relative weight, the association increased with age at the time of the initial measurement (eg, r .64 among 4-year-olds). Based on the initial and final total cholesterol determinations, the within-person standard deviation was 21 mg/dL and the coefficient of variation was 13%. Although the final total cholesterol level was within 5 mg/dL of the initial level for 18% of the children, the two determinations differed by ≥25 mg/dL for about 35% of the children and by ≥50 mg/dL for about 8%. Of the 149 children who had an initial cholesterol level ≥200 mg/dL, 34% (about five times the expected number) had a follow-up level that was similarly elevated whereas 25% had a subsequent measurement below 170 mg/dL. The results indicate that although an initial cholesterol level in early life is moderately predictive of subsequent levels, it may be difficult to interpret a single total cholesterol determination because of substantial within-person variability.

scholarly journals Diabetic retinopathy with or without clinically significant macular edema: The influencing factors

2016 ◽  
Vol 7 (2) ◽  
pp. 142-147
Author(s):  
Barsha Suwal ◽  
Jeevan Kumar Shrestha ◽  
Sagun Narayan Joshi ◽  
Ananda Kumar Sharma
Keyword(s):  
Diabetic Retinopathy ◽  
Glycemic Control ◽  
Macular Edema ◽  
Total Cholesterol ◽  
Cholesterol Level ◽  
Total Cholesterol Level ◽  
Density Lipoprotein ◽  
Diabetic Patients ◽  
Clinically Significant Macular Edema ◽  
Clinically Significant

Introduction: Diabetic retinopathy is the commonest micro vascular complication in patients with diabetes and remains a leading cause of blindness in people of working age group. Objective: to determine the prevalence of clinically significant macular edema (CSME) and the influence of systemic risk factors Materials and methods: It is a hospital based comparative study conducted in 220 eyes of 110 diabetic patients. DR was graded according to International Clinical Diabetic Retinopathy Severity Scale and CSME was defined according to Early Treatment Diabetic Retinopathy Study (ETDRS) system. The patients were grouped as 1) CSME group (DR and CSME in one or both eyes) and 2) Non- CSME group(CSME in none of the eyes but with any grade of DR).Level of glycosylated hemoglobin (HbA1C), serum total cholesterol, triglyceride (TG), low density lipoprotein (LDL), high density lipoprotein (HDL) and urine for albumin were studied in both groups. Results: CSME was present in 36% of 110 patients. Poor glycemic control and high total cholesterol level showed positive association with CSME (p<0.05). LDL and TG levels were higher and HDL lower in CSME group. However, no statistical significance was found. Conclusion: The CSME is significantly associated with poorer glycemic control and elevated total cholesterol level.

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