MODELLING OF NON-EQUILIBRIUM SYSTEMS: REACTION NETWORKS FOR BIOINSPIRED BEHAVIOUR

2021 ◽  
Author(s):  
ANNETTE F. TAYLOR
Keyword(s):  
Reaction Networks ◽  
Non Equilibrium

scholarly journals Parasitic Behavior in Competing Chemically Fueled Reaction Cycles

2021 ◽  
Author(s):  
Patrick S. Schwarz ◽  
Sudarshana Laha ◽  
Jacqueline Janssen ◽  
Tabea Huss ◽  
Job Boekhoven ◽  
...  
Keyword(s):  
Dynamic Behavior ◽  
Model Systems ◽  
Reaction Networks ◽  
Reaction Cycles ◽  
Non Equilibrium

Non-equilibrium, fuel-driven reaction cycles serve as model systems of the intricate reaction networks of life. Rich and dynamic behavior is observed when reaction cycles regulate assembly processes, such as phase...

scholarly journals Chemical Basis of Biological Homochirality during the Abiotic Evolution Stages on Earth

Symmetry ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 814 ◽  
Author(s):  
Josep M. Ribó ◽  
David Hochberg
Keyword(s):  
Symmetry Breaking ◽  
Chemical Evolution ◽  
Mirror Symmetry ◽  
Reaction Network ◽  
Reaction Networks ◽  
Stationary States ◽  
Cell Systems ◽  
Basic Model ◽  
Stochastic Distribution ◽  
Non Equilibrium

Spontaneous mirror symmetry breaking (SMSB), a phenomenon leading to non-equilibrium stationary states (NESS) that exhibits biases away from the racemic composition is discussed here in the framework of dissipative reaction networks. Such networks may lead to a metastable racemic non-equilibrium stationary state that transforms into one of two degenerate but stable enantiomeric NESSs. In such a bifurcation scenario, the type of the reaction network, as well the boundary conditions, are similar to those characterizing the currently accepted stages of emergence of replicators and autocatalytic systems. Simple asymmetric inductions by physical chiral forces during previous stages of chemical evolution, for example in astrophysical scenarios, must involve unavoidable racemization processes during the time scales associated with the different stages of chemical evolution. However, residual enantiomeric excesses of such asymmetric inductions suffice to drive the SMSB stochastic distribution of chiral signs into a deterministic distribution. According to these features, we propose that a basic model of the chiral machinery of proto-life would emerge during the formation of proto-cell systems by the convergence of the former enantioselective scenarios.

scholarly journals Reaction Networks as Systems for Resource Allocation: A Variational Principle for Their Non-Equilibrium Steady States

PLoS ONE ◽  
2012 ◽  
Vol 7 (7) ◽  
pp. e39849 ◽  
Author(s):  
Andrea De Martino ◽  
Daniele De Martino ◽  
Roberto Mulet ◽  
Guido Uguzzoni
Keyword(s):  
Resource Allocation ◽  
Variational Principle ◽  
Steady States ◽  
Reaction Networks ◽  
Non Equilibrium

scholarly journals Organocatalytic Control over a Fuel-Driven Transient Esterification Network

2020 ◽  
Author(s):  
Michelle van der Helm ◽  
Chang-Lin Wang ◽  
Mariano Macchione ◽  
Eduardo Mendes ◽  
Rienk Eelkema
Keyword(s):  
Chemical Change ◽  
Polymer System ◽  
Reaction Networks ◽  
Polymer Conformation ◽  
Controlled Processes ◽  
Full Control ◽  
Ester Formation ◽  
Driven System ◽  
Ester Yield ◽  
Non Equilibrium

<p>Signal transduction in living systems is the conversion of information into a chemical change and the principal process by which cells communicate. This process enables phenomena such as time-keeping and signal amplification. In nature, these functions are encoded in non-equilibrium (bio)chemical reaction networks (CRNs) controlled by enzymes. While these catalytically controlled processes are an integral part of biocatalytic pathways, man-made analogs are rare. Here, we incorporate catalysis in an artificial fuel driven out-of-equilibrium CRN. The study entails the design of an organocatalytically controlled fuel driven esterification CRN, where the forward (ester formation) and backward reaction (ester hydrolysis) are controlled by varying the ratio of two different organocatalysts: pyridine and imidazole. This catalytic regulation enables full control over ester yield and lifetime. The fuel-driven strategy is subsequently used in the design of a responsive polymer system, where transient polymer conformation and aggregation can be controlled through variation of fuel and catalysts levels. Altogether, we show how organocatalysis is an important tool to exert control over a man-made fuel driven system and induce a change in a macromolecular superstructure, as ubiquitously found in natural non-equilibrium systems. </p>

scholarly journals Lyapunov Functions, Stationary Distributions, and Non-equilibrium Potential for Reaction Networks

2015 ◽  
Vol 77 (9) ◽  
pp. 1744-1767 ◽  
Author(s):  
David F. Anderson ◽  
Gheorghe Craciun ◽  
Manoj Gopalkrishnan ◽  
Carsten Wiuf
Keyword(s):  
Lyapunov Functions ◽  
Equilibrium Potential ◽  
Reaction Networks ◽  
Stationary Distributions ◽  
Non Equilibrium

scholarly journals Organocatalytic Control over a Fuel-Driven Transient Esterification Network

2020 ◽  
Author(s):  
Michelle van der Helm ◽  
Chang-Lin Wang ◽  
Mariano Macchione ◽  
Eduardo Mendes ◽  
Rienk Eelkema
Keyword(s):  
Chemical Change ◽  
Polymer System ◽  
Reaction Networks ◽  
Polymer Conformation ◽  
Controlled Processes ◽  
Full Control ◽  
Ester Formation ◽  
Driven System ◽  
Ester Yield ◽  
Non Equilibrium

<p>Signal transduction in living systems is the conversion of information into a chemical change and the principal process by which cells communicate. This process enables phenomena such as time-keeping and signal amplification. In nature, these functions are encoded in non-equilibrium (bio)chemical reaction networks (CRNs) controlled by enzymes. While these catalytically controlled processes are an integral part of biocatalytic pathways, man-made analogs are rare. Here, we incorporate catalysis in an artificial fuel driven out-of-equilibrium CRN. The study entails the design of an organocatalytically controlled fuel driven esterification CRN, where the forward (ester formation) and backward reaction (ester hydrolysis) are controlled by varying the ratio of two different organocatalysts: pyridine and imidazole. This catalytic regulation enables full control over ester yield and lifetime. The fuel-driven strategy is subsequently used in the design of a responsive polymer system, where transient polymer conformation and aggregation can be controlled through variation of fuel and catalysts levels. Altogether, we show how organocatalysis is an important tool to exert control over a man-made fuel driven system and induce a change in a macromolecular superstructure, as ubiquitously found in natural non-equilibrium systems. </p>

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