Common Causes of Failure in Tissue Transplant and the Preventive Measures

Author(s):  
Zhu Shen-Xiu
2015 ◽  
Vol 69 (5-6) ◽  
pp. 443-452
Author(s):  
Marjan Kosec ◽  
Natasa Sterbenc ◽  
Janko Mrkun ◽  
Igor Klobucar ◽  
Primoz Klinc

The most frequent problems in horses reproduction are generally divided into those of infectious and non infectious etiology. Common causes of infectious diseases are usual?ly viruses and bacteria, and less frequently protozoa, mykoplasma and fungi. In this work there are presented the most important fact about sexually transmitted diseases, their clinical picture, risk factors, preventive measures as well as measures to prevent and eradicate the diseases. The biggest risk factor for sexually transmitted diseases in horses are breeding stallions, both in natural mating and in artificial insemination. Therefore, in order to prevent genital infections in horses, it is essential that the stallions used for breeding are healthy (non-infected). That can be determined with certainty only if the stallions are examined (tested) just before the breeding season on most frequent sexually transmitted diseases (CEM,EAV). It is well known that in most cases the clinical picture of sexually transmitted diseses is not manifested on genitals. As well, variations in clinical picture can be expected also in mares, depending on the stage of the disease and its etiology. Harms arising from sexually transmitted diseases can be divided into direct and indirect. Direct damage occurs in the form of endometritis, miscarriage, stillbirths and births of weak foals, and indirect in restricting the traffic of infected and suspicios animals, isolation of the infected ones as well as medical treatment and interrupting mating.


1990 ◽  
Vol 10 (2) ◽  
pp. 119-126 ◽  
Author(s):  
Claudio Ronco ◽  
Mariano Feriani ◽  
Stefano Chiaramonte ◽  
Alessandra Brendolan ◽  
Luisa Bragantini ◽  
...  

Pathophysiology of peritoneal ultrafiltration is analyzed in the present study. Peritoneal equilibration test is the easiest procedure to study in detail the possible causes of failure to control the ultrafiltration rate in patients undergoing peritoneal dialysis. Membrane failure, reduction in peritoneal blood flow, excessive lymphatic reabsorption catheter malposition, and fluid sequestration are the most common causes of ultrafiltration loss. Pharmacologic manipulation of peritoneal membrane, correction of mechanical inconvenients, reduction in peritonitis rate and in the level of immunostimulation of the mesotelial macrophages, together with a careful policy in terms of glucose concentration in the dialysate and dwell times may contribute not only to treat different forms of ultrafiltration loss but also to prevent their incidence.


2016 ◽  
Vol 10 (01) ◽  
pp. 144-147 ◽  
Author(s):  
Sadia Tabassum ◽  
Farhan Raza Khan

ABSTRACTInappropriate mechanical debridement, persistence of bacteria in the canals and apex, poor obturation quality, over and under extension of the root canal filling, and coronal leakage are some of the commonly attributable causes of failure. Despite the high success rate of endodontic treatment, failures do occur in a large number of cases and most of the times can be attributed to the already stated causes. With an ever increasing number of endodontic treatments being done each day, it has become imperative to avoid or minimize the most fundamental of reasons leading to endodontic failure. This paper reviews the most common causes of endodontic failure along with radiographic examples.


2019 ◽  
Vol 35 (06) ◽  
pp. 627-632
Author(s):  
Likith Reddy ◽  
Daniel Lee ◽  
Aurora Vincent ◽  
Tom Shokri ◽  
Mofiyinfolu Sokoya ◽  
...  

AbstractMandibular fractures are the most common facial fractures that need surgical intervention. If untreated, these fractures affect a patient's occlusion, degree of mouth opening, and facial symmetry, and could cause infection with significant pain. The goal of any surgical intervention is to restore the preinjury occlusion, even if the preinjury occlusion is abnormal. Initial therapies, whether surgical or conservative, are not always successful, however, and revision or delayed surgical intervention can be challenging. Herein, we review common causes of failure of primary surgical management of mandibular fractures and provide tips to successful secondary intervention.


2020 ◽  
Vol 405 ◽  
pp. 312-317
Author(s):  
Patrícia Hanusová ◽  
Peter Palček ◽  
Mária Chalupová ◽  
Milan Uhríčik

This paper deals with applications of biomaterial in the human body. Each biomaterial is characterized by biofunctionality and biocompatibility [1]. The choice of biomaterial for medical applications is established on mechanical properties. Therefor the Ti6Al4V alloys, which properties are relatively low modulus, good fatigue strength, formability, machinability, corrosion resistance [2], are most widely used in biomedical replacements, implants, and prosthesis. Despite the excellent properties of the titanium alloy, endoprosthesis often fails and the hip replacement is necessary. Common causes are overloading and cracking, static or dynamic. Other causes of failure include injury, implantation failure, manufacturing inaccuracies, and non-compliance with the manufacturing process.


2019 ◽  
Vol 33 (05) ◽  
pp. 459-465
Author(s):  
Matthew Nagle ◽  
Aaron Glynn

AbstractInstability is one of the most common causes of failure in total knee arthroplasty. Traditionally, it has been classified into three types: extension instability, flexion instability, and hyperextension instability. More recently, a fourth type of instability has been proposed, namely “midflexion instability” (MFI). Whether MFI is distinct from the aforementioned types of instability is contentious, and at present, the condition is yet to be clearly defined. This article reviews the current literature and identifies the best available evidence relevant to the concept of MFI. Our aim is to present an overview of the proposed causes and mechanisms for MFI. By doing so, we also aim to provide a focus on how MFI presents, whether it is indeed a discrete form of instability, and if it influences clinical results.


Author(s):  
Thuc-Quyen D. Nguyen ◽  
James Guido DiStefano ◽  
Andrew Y. Park ◽  
Gerd Diederichs ◽  
Jenni M. Buckley ◽  
...  

The reverse design of the total shoulder arthroplasty has been utilized for elderly patients with severely degenerated glenohumoral joints that are rotator cuff deficient. One of the most common causes of failure in shoulder arthroplasty involves loosening or catastrophic failure of the glenoid component. Such problems can be related to suboptimal fixation due to bone loss from fractures, severe degenerative changes and from previous failed arthroplasty surgery [1]. This emphasizes the need to secure the glenoid component with sound screw purchase beyond the glenoid vault. However, such fixation can often be tenuous as scapula bone quality is heterogeneous with a wide variation across short distances [2, 3]. Moreover, it can be difficult to identify regions with the best bone stock intraoperatively. This often requires multiple passes with the drill, which leads to further bone loss and potential decreased screw purchase. Thus, it is important for the surgeon to have a firm understanding of scapular anatomy with potential screw trajectories in mind.


2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Cattram D. Nguyen ◽  
John B. Carlin ◽  
Katherine J. Lee

AbstractMultiple imputation is a recommended method for handling incomplete data problems. One of the barriers to its successful use is the breakdown of the multiple imputation procedure, often due to numerical problems with the algorithms used within the imputation process. These problems frequently occur when imputation models contain large numbers of variables, especially with the popular approach of multivariate imputation by chained equations. This paper describes common causes of failure of the imputation procedure including perfect prediction and collinearity, focusing on issues when using Stata software. We outline a number of strategies for addressing these issues, including imputation of composite variables instead of individual components, introducing prior information and changing the form of the imputation model. These strategies are illustrated using a case study based on data from the Longitudinal Study of Australian Children.


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