Bioboard

2009 ◽  
Vol 13 (03) ◽  
pp. 5-20
Keyword(s):  
Clinical Trial ◽  
Stem Cell ◽  
North America ◽  
South Korea ◽  
Adult Stem Cells ◽  
Vaccine Development ◽  
Research Centre ◽  
Ips Cell ◽  
Bird Flu ◽  
Flu Vaccine

AUSTRALIA – First iPS Cell Line Puts Australia in the Lead of Stem Cell Research. AUSTRALIA – New Treatment Hope for Prostate Cancer. CHINA – AIDS Is China's Top Killer Among Infectious Diseases. CHINA – Anti-bird Flu Drug for Human Clinical Trial Approved by China. CHINA – China Plans 120 Billion Dollar Health Reform By 2011. CHINA – 13 000 Fowl Culled in China After Bird flu. CHINA – China-Russia Joint Research Center. CHINA – Pig's Adult Stem Cells Produce Better Skins. CHINA – More Health Scares Amid Slowdown, Warns China. INDIA – Indian Experts Find Bacteria to Beat Global Heat. INDIA – Two Indian Firms to set up Pre-clinical Trial Units in Malaysia. JAPAN – Breakthrough in Universal Flu Vaccine Development. SINGAPORE – Taiwan Pork Banned by AVA. SINGAPORE – Stem-Cell Treatment For Joint Pain Gives New Hope. SINGAPORE – Next Generation Healthcare Information System. SINGAPORE – Top US University Sets up Research Centre in Singapore. SINGAPORE – Increase in Life-saving Umbilical Cord Donations. SINGAPORE – Singapore and China Scientists Report Breakthrough Research in Psoriasis. SOUTH KOREA – Harmful Bacteria in French Baby Formula. SOUTH KOREA – World's First Cloned Wolves to Test Reproductive Fitness. TAIWAN – Genetic Testing on the Rise. TAIWAN – Chinese Herbal Medicines Contain Western Drug Ingredients. VIETNAM – Bird Flu Strikes in Five Provinces in Vietnam. VIETNAM – Opening of Vietnam's First Stem Cell Bank, "MekoStem". VIETNAM – Hanoi Suffers Worst Measles Outbreak in Decade. OTHER REGIONS — EUROPE – Social Networking = Disease? OTHER REGIONS — EUROPE – Cancer Morbidity 'to Double in 40 Years'. OTHER REGIONS — NORTH AMERICA – Scientists Close in on 'Universal' Vaccine for Flu. OTHER REGIONS — NORTH AMERICA – Hong Kong and US Scientists Develop New Bird Flu Vaccine.

Bioboard

2008 ◽  
Vol 12 (08) ◽  
pp. 5-17
Keyword(s):  
South Korea ◽  
Local Governments ◽  
Tamil Nadu ◽  
Joint Venture ◽  
The Philippines ◽  
Treatment Center ◽  
Bird Flu ◽  
Flu Vaccine ◽  
Biomedical Electronics ◽  
Set Up

AUSTRALIA — New Meningococcal Test to Identify Genetic Predisposition AUSTRALIA — Scientists Discover the Double Life of Proteins AUSTRALIA — Gene Discovery Offers Cancer Hope CHINA — The American Psychiatric Association's Awards for Young Scientists Encourage Research Expertise in China CHINA — DuPont Partners with China to Increase Farm Productivity CHINA — Deadly Enterovirus Afflicts Chinese Children CHINA — CAS Researchers Decode Genome of Mosquito-Killing Bacterium CHINA — CAS, Local Governments to Jointly Set Up a Biomedical Institute in Suzhou CHINA — Chinese and US Scientists Map Papaya Genes CHINA — Genzyme to Build New R&D Center in Beijing INDIA — Avesthagen Launches Bioactive Teestar INDIA — Scientists Find Kala-azar Protein INDIA — Bayer Launches Disease-Resistant Hybrid Rice Arize Dhani INDIA — SCHOTT Forms Pharmaceutical Joint Venture in India INDIA — IIT Mumbai Develops Chip to Detect Myocardial Infarction INDIA — Tamil Nadu Plans Poison Treatment Center in Every District INDIA — RFCL Opens Integrated Manufacturing Plant in India JAPAN — Pfizer to Launch Champix® – The First Prescription Oral Smoking Cessation Aid in the Country NEW ZEALAND — Asthma Linked to High Fat Diet PHILIPPINES — Surge in Dengue Cases in the Philippines SOUTH KOREA — Bird Flu Outbreaks Spread in South Korea SINGAPORE — Edwards Lifesciences Opens Its First Heart Valve Manufacturing Facility in Singapore SINGAPORE — Bioimaging and Stem Cell Research in Singapore gets a Million Dollar Boost from Latest Grant Calls by A*STAR SINGAPORE — Maccine Receives Bio-Industry Award for Best Preclinical or Clinical CRO in Asia TAIWAN — New Group for Biomedical Electronics Established TAIWAN — Stroke Evaluation Indicator Discovered VIETNAM — Vietnam Bird Flu Vaccine Returns Positive Results

Bioboard

2009 ◽  
Vol 13 (02) ◽  
pp. 5-22
Keyword(s):  
North America ◽  
Medical Tourism ◽  
Vaccine Development ◽  
Drug Hypersensitivity ◽  
Bird Species ◽  
Hypersensitivity Syndrome ◽  
Direct Access ◽  
Bird Flu ◽  
Resistant Tuberculosis ◽  
Diabetes Drug

AUSTRALIA – Mosquito Parasite Could Control Dengue CHINA – China has Twice the Global Average of Drug-Resistant Tuberculosis CHINA – 80 000 Antibiotics Abuse-related Deaths Annually CHINA – Bird Flu Found in Chicken from China CHINA – China on Alert following Bird Flu Death CHINA – Chinese Dairies to Compensate Tainted Milk Victims' Families CHINA – New Insulin Resistance Tricks Found CHINA – World's First Plant Chromosome Atlas CHINA – Project Launched to Study Structure of Proteins CHINA – Fake Diabetes Drug Linked to Two Deaths CHINA – Birth Defects Rising in Polluted China INDIA – India Culls Poultry in Darjeeling After Bird Flu INDIA – India Introduces Second-Line Anti-retroviral Treatment in Eight States INDIA – Indian Medical Tourism to Reach US$1.9 billion by 2015 INDIA – Canadian and Indian Ministers Sign Pact on Agriculture Cooperation INDIA – 6000 year-old Rice Species Discovered in Meghalaya INDIA – Genetics to Help Conserve Rare Bird Species JAPAN – Coating the Protein Enhances Disease-fighting Capability JAPAN – Scientists Isolate Genes that Made 1918 Flu Lethal JAPAN – Researchers in Japan Develop All-round Flu Vaccine PHILIPPINES – Ebola Reston Virus Found in Filipino Farm Worker SINGAPORE – New Method to Create iPS Cells SINGAPORE – Ray of Hope for Liver Cancer Sufferers SINGAPORE – Bacteria Improve Energy and Cost Efficiency in Water Treatment TAIWAN – Secrets of “Speciation” Gene Unravelled TAIWAN – Initial Breakthrough in Poultry Vaccine Development TAIWAN – Taiwan Gains Direct Access to WHO VIETNAM – Doctors Report First Drug Hypersensitivity Syndrome VIETNAM – Public Advised Serious Caution Against Bird Flu NORTH AMERICA – Kids of Pregnant Drinking Mums will Like Booze NORTH AMERICA – High Functional Diversity in Mycobacterium Tuberculosis Driven By Genetic Drift And Human Demography NORTH AMERICA – Newly Discovered Tuberculosis Protein May Help Explain Bacterium's Resilience NORTH AMERICA – U.S. Patent For Diagnostic Technology Awarded To URMC, Lighthouse Biosciences EUROPE – Structure Mediating Spread of Antibiotic Resistance Discovered EUROPE – New EU Pesticide Regulations Could Undermine Battle against Malaria EUROPE – iPill – The Smart Drug Delivery that can “Call” the Doctor EUROPE – What Drives Locusts to Swarm

BioBoard

2007 ◽  
Vol 11 (03) ◽  
pp. 129-138
Keyword(s):  
South Korea ◽  
Generic Drugs ◽  
Cancer Therapeutics ◽  
Cooperative Research ◽  
Indian Government ◽  
Bird Flu ◽  
Cooperative Research Center ◽  
Flu Vaccine ◽  
Set Up ◽  
National Disaster

Australia — New Cooperative Research Center for Cancer Therapeutics in Melbourne. Australia — WEHI Collaborates with Genentech to Develop New Cancer Drugs. Australia — Australia Prepares to Vaccinate its Entire Population Against Bird Flu. China — China Revokes Licenses of 160 Drug Firms. China — Three More National Laboratories to be Set up at CAS. China — Covance Expands Operations in China. China — CAS Launches a New Round of Academician Selection with Strict Procedures. China — China Slashes Cost of Overpriced Drugs. China — New Diabetic Drug Manufactured in Shanghai. Japan — Japan Confirms 32nd Mad Cow Case. Japan — New Bird Flu Outbreak Suspected in Japan. Indonesia — Indonesia to Declare Bird Flu a National Disaster. Indonesia — Baxter Collaborates with the Indonesian Government. Indonesia — Indonesia Develops a Bird Flu Vaccine. India — India to Carry Out First Multi-centric Clinical Trial with Stem Cells. India — Lotus Labs and Labindia Team Up to Build a Clinical Research Academy. India — Bangalore to Build Knowledge City. India — Indian Companies to Bid for Merck's Generics Business. India — India and Croatia Pledge One million Euros for Scientific Research. India — India to Lead in Global Stem Cell Market by 2010. India — Biotech Leaders Receive Indian Government Awards. Malaysia — Malaysia Opens a New Laboratory for Hazardous Disease Research. Philippines — Philippines Bans Imports of Live Birds and Poultry from Japan. Singapore — Singapore Keeping up Vigilance Against Infectious Diseases. Singapore — Singapore Health Ministry Considering Legislation on Biomedical Research. Singapore — TNT Appoints Onno Boots as South East Asia's Regional Managing Director. South Korea — South Korea Aims to Become Top 10 Science Nation by 2010. Taiwan — Taiwan Works on Bird Flu Vaccine. Taiwan — Taiwan Introduces World's First DNA chip. Thailand — Bird Flu Strikes in Thailand Again. Thailand — Thai Pharma Industry Against Thai Government's Decision to Produce Generic Drugs.

Bird flu vaccine not up to scratch

Nature ◽  
2005 ◽  
Author(s):  
Declan Butler
Keyword(s):  
Bird Flu ◽  
Flu Vaccine

Application of Nanomaterials in Regulating the Fate of Adipose-derived Stem Cells

2021 ◽  
Vol 16 (1) ◽  
pp. 3-13
Author(s):  
Lang Wang ◽  
Yong Li ◽  
Maorui Zhang ◽  
Kui Huang ◽  
Shuanglin Peng ◽  
...  
Keyword(s):  
Stem Cells ◽  
Stem Cell ◽  
Stem Cell Research ◽  
Adult Stem Cells ◽  
Adipose Derived Stem Cells ◽  
Proliferation And Differentiation ◽  
Recent Developments ◽  
Good Biocompatibility ◽  
Regulatory Effects ◽  
New Treatment

Adipose-derived stem cells are adult stem cells which are easy to obtain and multi-potent. Stem-cell therapy has become a promising new treatment for many diseases, and plays an increasingly important role in the field of tissue repair, regeneration and reconstruction. The physicochemical properties of the extracellular microenvironment contribute to the regulation of the fate of stem cells. Nanomaterials have stable particle size, large specific surface area and good biocompatibility, which has led them being recognized as having broad application prospects in the field of biomedicine. In this paper, we review recent developments of nanomaterials in adipose-derived stem cell research. Taken together, the current literature indicates that nanomaterials can regulate the proliferation and differentiation of adipose-derived stem cells. However, the properties and regulatory effects of nanomaterials can vary widely depending on their composition. This review aims to provide a comprehensive guide for future stem-cell research on the use of nanomaterials.

scholarly journals GSK3β, a Master Kinase in the Regulation of Adult Stem Cell Behavior

Cells ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 225
Author(s):  
Claire Racaud-Sultan ◽  
Nathalie Vergnolle
Keyword(s):  
Stem Cells ◽  
Stem Cell ◽  
Adult Stem Cells ◽  
Glycogen Synthase ◽  
Inflammatory Diseases ◽  
Adult Stem Cell ◽  
Leukemic Cells ◽  
Cell Phenotype ◽  
Epithelial Regeneration ◽  
Cell Functions

In adult stem cells, Glycogen Synthase Kinase 3β (GSK3β) is at the crossroad of signaling pathways controlling survival, proliferation, adhesion and differentiation. The microenvironment plays a key role in the regulation of these cell functions and we have demonstrated that the GSK3β activity is strongly dependent on the engagement of integrins and protease-activated receptors (PARs). Downstream of the integrin α5β1 or PAR2 activation, a molecular complex is organized around the scaffolding proteins RACK1 and β-arrestin-2 respectively, containing the phosphatase PP2A responsible for GSK3β activation. As a consequence, a quiescent stem cell phenotype is established with high capacities to face apoptotic and metabolic stresses. A protective role of GSK3β has been found for hematopoietic and intestinal stem cells. Latters survived to de-adhesion through PAR2 activation, whereas formers were protected from cytotoxicity through α5β1 engagement. However, a prolonged activation of GSK3β promoted a defect in epithelial regeneration and a resistance to chemotherapy of leukemic cells, paving the way to chronic inflammatory diseases and to cancer resurgence, respectively. In both cases, a sexual dimorphism was measured in GSK3β-dependent cellular functions. GSK3β activity is a key marker for inflammatory and cancer diseases allowing adjusted therapy to sex, age and metabolic status of patients.

Equitable Access to Research Benefits: Considerations for COVID-19 Vaccine Development and Clinical Trial Crossover

2021 ◽  
Vol 21 (3) ◽  
pp. 86-88
Author(s):  
Danish Zaidi ◽  
Jennifer Miller ◽  
Tanvee Varma ◽  
Dowin Boatright ◽  
Phoebe Friesen
Keyword(s):  
Clinical Trial ◽  
Vaccine Development ◽  
Equitable Access

scholarly journals The dyskerin ribonucleoprotein complex as an OCT4/SOX2 coactivator in embryonic stem cells

eLife ◽  
2014 ◽  
Vol 3 ◽  
Author(s):  
Yick W Fong ◽  
Jaclyn J Ho ◽  
Carla Inouye ◽  
Robert Tjian
Keyword(s):  
Stem Cell ◽  
Es Cells ◽  
Embryonic Stem ◽  
In Vitro Transcription ◽  
Specific Gene ◽  
Transcriptional Level ◽  
Ips Cell ◽  
Ribonucleoprotein Complex ◽  
Transcription System

Acquisition of pluripotency is driven largely at the transcriptional level by activators OCT4, SOX2, and NANOG that must in turn cooperate with diverse coactivators to execute stem cell-specific gene expression programs. Using a biochemically defined in vitro transcription system that mediates OCT4/SOX2 and coactivator-dependent transcription of the Nanog gene, we report the purification and identification of the dyskerin (DKC1) ribonucleoprotein complex as an OCT4/SOX2 coactivator whose activity appears to be modulated by a subset of associated small nucleolar RNAs (snoRNAs). The DKC1 complex occupies enhancers and regulates the expression of key pluripotency genes critical for self-renewal in embryonic stem (ES) cells. Depletion of DKC1 in fibroblasts significantly decreased the efficiency of induced pluripotent stem (iPS) cell generation. This study thus reveals an unanticipated transcriptional role of the DKC1 complex in stem cell maintenance and somatic cell reprogramming.

BioBoard

2006 ◽  
Vol 10 (22) ◽  
pp. 1267-1273
Keyword(s):  
Hong Kong ◽  
New Zealand ◽  
South Korea ◽  
Drug Approval ◽  
Influenza Virus Vaccine ◽  
Biomedical Ethics ◽  
Bird Flu ◽  
H5n1 Avian Influenza Virus ◽  
H5n1 Avian Influenza ◽  
Speed Up

Australia — Politicians Chastise Australia's Science Institute. Australia — GE Healthcare and WA Government Collaborate on Cell-based Imaging Equipment. Australia — The Goal of Imugene's H5N1 Avian Influenza Virus Vaccine. China — East China University Sparks Debate on Education Funding. China — 3D Map of SARS virus Drawn. China — Researchers Comment that Global Loss of Biodiversity is Harming Ocean Bounty. China — China Insists that there are No Variant Bird Flu Strain. China — Gene involved in Eye Lens Development. China — Cancer-causing Dye Found in Duck Eggs in China. Hong Kong — Scientists in Hong Kong Found Clues to Pandemic Bird Flu. Hong Kong — Hong Kong Bird Flu Expert Picked to Head WHO. India — Ranbaxy Signs Licensing Agreement with Swiss Company Debiopharm. India — Indian Biotechnology Park. Japan — Japan's New Premier Chases Innovation. Japan — Japan Reforms Screening to Speed up Drug Approval. New Zealand — New Zealand Invests in Neurology Project. South Korea — South Korea Gives Funding Boost to Stem-Cell Research. South Korea — South Korea Plans to Inject $253 million into Biotech. South Korea — Scientists Discover Stem Cells Might Help to Treat Mental Illness. Singapore — Renowned French Cancer Development Biologist Moves to Singapore's Biopolis. Singapore — Singapore Plans to Build Bigger Heart Center to Handle Spiraling Patient Numbers. Singapore — New Centre for Biomedical Ethics at NUS. Taiwan — Taiwan's CDC Places Order for H5N1 Vaccine. Taiwan — Tenders sought for Pingtung Agricultural Biotech Park Housing.

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