TRANSITION AND LAMINAR FLOWS IN A REALISTIC GEOMETRY OF HUMAN UPPER AIRWAY

Author(s):  
REZA TABE ◽  
ROOHOLLAH RAFEE ◽  
MOHAMMAD SADEGH VALIPOUR ◽  
GOODARZ AHMADI

In this study, a realistic respiratory airway model extending from oral to the end of the trachea including all the key details of the passage was produced. A series of CT scan images were used to generate the topological data of airway cross-sections that were used to generate the computational model, as well as the three-dimensional (3D) printed model of the passage for experimental study. The airflow velocity field and pressure drop in the airway for different breathing rates of 5, 7.5, 10, and 12.5[Formula: see text]L/min were investigated numerically (by laminar and transition models) and experimentally. The velocity distributions, pressure variation, and streamlines along the oral–trachea airway model were studied. The maximum pressure drop was shown to occur in the narrowest part of the larynx region. It was also concluded that the laryngeal jet could significantly influence the airway flow patterns in the trachea. A comparison between the numerical results and experimental data showed that the transition [Formula: see text]–kl–[Formula: see text] model can give better predictions of pressure losses, especially for flow rates higher than 10[Formula: see text]L/min. The simulation results for the velocity profiles in the trachea were also compared with the available particle image velocimetry (PIV) data and earlier simulations. Despite inter-personal variability and difference in the flow regime, the qualitative agreement was found.

2007 ◽  
Vol 102 (3) ◽  
pp. 1178-1184 ◽  
Author(s):  
Mark Brouns ◽  
Santhosh T. Jayaraju ◽  
Chris Lacor ◽  
Johan De Mey ◽  
Marc Noppen ◽  
...  

Patients referred for treatment of tracheal stenosis typically are asymptomatic until critical narrowing of the airway occurs, which then requires immediate intervention. To understand how tracheal stenosis affects local pressure drops and explore how a dramatic increase in pressure drop could possibly be detected at an early stage, a computational fluid dynamics (CFD) study was undertaken. We assessed flow patterns and pressure drops over tracheal stenoses artificially inserted into a realistic three-dimensional upper airway model derived from multislice computed tomography images obtained in healthy men. Solving the Navier-Stokes equations (with a Yang-shih k-ε turbulence model) for different degrees of tracheal constriction located approximately one tracheal diameter below the glottis, the simulated pressure drop over the stenosis (ΔP) was seen to dramatically increase only when well over 70% of the tracheal lumen was obliterated. At 30 l/min, ΔP increased from 7 Pa for a 50% stenosis to, respectively, 46 and 235 Pa for 80% and 90% stenosis. The pressure-flow relationship in the entire upper airway model (between mouth and end of trachea) in the flow range 0–60 l/min showed a power law relationship with best-fit flow exponent of 1.77 in the absence of stenosis. The exponent became 1.92 and 2.00 in the case of 60% and 85% constriction, respectively. The present simulations confirm that the overall pressure drop at rest is only affected in case of severe constriction, and the simulated flow dependence of pressure drop suggests a means of detecting stenosis at a precritical stage.


Author(s):  
Matthew McCormack ◽  
Fengzhou Fang ◽  
Jufan Zhang

AbstractConjugate heat transfer is numerically investigated using a three-dimensional computational fluid dynamics approach in various microchannel geometries to identify a high-performance cooling method for piezoelectric ceramic stacks and spindle units in high-precision machines. Straight microchannels with rectangular cross sections are first considered, showing the performance limitations of decreasing the size of the microchannels, so other solutions are needed for high applied heat fluxes. Next, many microchannel designs, focusing on streamwise geometric variation, are compared to straight channels to assess their performances. Sinusoidally varying channels produce the highest heat transfer rates of those studied. Thus, their optimization is considered at a channel width and height of 35 and 100 μm, respectively. Heat transfer increases as the amplitude and spatial frequencies of the channels increase due to increased interfacial surface area and enhanced Dean flow. The highest performance efficiencies are observed at intermediate levels of amplitude and frequency, with efficiency decreasing as these geometric parameters are increased further at the onset of flow separation. The sinusoidal channel geometries are then optimized with respect to minimizing the system’s pressure drop for all applied heat fluxes between 5690 and 6510 kW/m2. Doing so created an optimal geometry curve and showed that all geometries in this region had amplitudes close to 40 μm. Therefore, imposing a fixed heat flux requirement for a case study of cooling piezoelectric ceramics, the optimized sinusoidal geometry decreases the system pressure drop by 79% relative to a straight channel while maintaining a larger minimum feature size.


2013 ◽  
Vol 716 ◽  
pp. 280-315 ◽  
Author(s):  
H. V. Moradi ◽  
J. M. Floryan

AbstractAnalysis of pressure losses in laminar flows through annuli fitted with longitudinal grooves has been carried out. The additional pressure gradient required in order to maintain the same flow rate in the grooved annuli, as well as in the reference smooth annuli, is used as a measure of the loss. The groove-induced changes can be represented as a superposition of a pressure drop due to a change in the average position of the bounding cylinders and a pressure drop due to flow modulations induced by the shape of the grooves. The former effect can be evaluated analytically while the latter requires explicit computations. It has been demonstrated that a reduced-order model is an effective tool for extraction of the features of groove geometry that lead to flow modulations relevant to drag generation. One Fourier mode from the Fourier expansion representing the annulus geometry is sufficient to predict pressure losses with an accuracy sufficient for most applications in the case of equal-depth grooves. It is shown that the presence of the grooves may lead to a reduction of pressure loss in spite of an increase of the surface wetted area. The drag-decreasing grooves are characterized by the groove wavenumber $M/ {R}_{1} $ being smaller than a certain critical value, where $M$ denotes the number of grooves and ${R}_{1} $ stands for the radius of the annulus. This number marginally depends on the groove amplitude and does not depend on the flow Reynolds number. It is shown that the drag reduction mechanism relies on the re-arrangement of the bulk flow that leads to the largest mass flow taking place in the area of the largest annulus opening. The form of the optimal grooves from the point of view of the maximum drag reduction has been determined. This form depends on the type of constraints imposed. In general, the optimal shape can be described using the reduced-order model involving only a few Fourier modes. It is shown that in the case of equal-depth grooves, the optimal shape can be approximated using a special form of trapezoid. In the case of unequal-depth grooves, where the groove depth needs to be determined as part of the optimization procedure, the optimal geometry, consisting of the optimal depth and the corresponding optimal shape, can be approximated using a delta function. The maximum possible drag reduction, corresponding to the optimal geometry, has been determined.


2020 ◽  
Vol 31 (6) ◽  
pp. 900-903
Author(s):  
Jesse Xu ◽  
Cameron Sullivan ◽  
Hui Xin Ong ◽  
Jonathan P Williamson ◽  
Daniela Traini ◽  
...  

Abstract Airway stents are used to manage central airway obstructions by restoring airway patency. Current manufactured stents are limited in shape and size, which pose issues in stent fenestrations needed to be manually created to allow collateral ventilation to airway branches. The precise location to place these fenestrations can be difficult to predict based on 2-dimensional computed tomography images. Inspiratory computed tomography scans were obtained from 3 patients and analysed using 3D-Slicer™, Blender™ and AutoDesk® Meshmixer™ programmes to obtain working 3D-airway models, which were 3D printed. Stent customizations were made based on 3D-model dimensions, and fenestrations into the stent were cut. The modified stents were then inserted as per usual technique. Two patients reported improved airway performance; however, stents were later removed due to symptoms related to in-stent sputum retention. In a third patient, the stent was removed a few weeks later due to the persistence of fistula leakage. The use of a 3D-printed personalized airway model allowed for more precise stent customization, optimizing stent fit and allowing for cross-ventilation of branching airways. We determine that an airway model is a beneficial tool for stent optimization but does not prevent the development of some stent-related complications such as airway secretions.


2018 ◽  
Vol 25 (4) ◽  
pp. 349-354 ◽  
Author(s):  
Alfonso Fiorelli ◽  
Roberto Scaramuzzi ◽  
Ivana Minerva ◽  
Emanuele De Ruberto ◽  
Teresa Califano ◽  
...  

2003 ◽  
Vol 3 ◽  
pp. 208-219
Author(s):  
A.M. Ilyasov

In this paper we propose a model for determining the pressure loss due to friction in each phase in a three-layer laminar steady flow of immiscible liquid and gas flow in a flat channel. This model generalizes an analogous problem for a two-layer laminar flow, proposed earlier. The relations obtained in the final form for the pressure loss due to friction in liquids can be used as closing relations for the three-fluid model. These equations take into account the influence of interphase boundaries and are an alternative to the approach used in foreign literature. In this approach, the wall and interphase voltages are approximated by the formulas for a single-phase flow and do not take into account the mutual influence of liquids on the loss of pressure on friction in phases. The distribution of flow parameters in these two models is compared.


Author(s):  
Zhonghua Sun

Three-dimensional (3D) printing is increasingly used in medical applications with most of the studies focusing on its applications in medical education and training, pre-surgical planning and simulation, and doctor-patient communication. An emerging area of utilising 3D printed models lies in the development of cardiac computed tomography (CT) protocols for visualisation and detection of cardiovascular disease. Specifically, 3D printed heart and cardiovascular models have shown potential value in the evaluation of coronary plaques and coronary stents, aortic diseases and detection of pulmonary embolism. This review article provides an overview of the clinical value of 3D printed models in these areas with regard to the development of optimal CT scanning protocols for both diagnostic evaluation of cardiovascular disease and reduction of radiation dose. The expected outcomes are to encourage further research towards this direction.


Author(s):  
Matthew J. Genge

Drawings, illustrations, and field sketches play an important role in Earth Science since they are used to record field observations, develop interpretations, and communicate results in reports and scientific publications. Drawing geology in the field furthermore facilitates observation and maximizes the value of fieldwork. Every geologist, whether a student, academic, professional, or amateur enthusiast, will benefit from the ability to draw geological features accurately. This book describes how and what to draw in geology. Essential drawing techniques, together with practical advice in creating high quality diagrams, are described the opening chapters. How to draw different types of geology, including faults, folds, metamorphic rocks, sedimentary rocks, igneous rocks, and fossils, are the subjects of separate chapters, and include descriptions of what are the important features to draw and describe. Different types of sketch, such as drawings of three-dimensional outcrops, landscapes, thin-sections, and hand-specimens of rocks, crystals, and minerals, are discussed. The methods used to create technical diagrams such as geological maps and cross-sections are also covered. Finally, modern techniques in the acquisition and recording of field data, including photogrammetry and aerial surveys, and digital methods of illustration, are the subject of the final chapter of the book. Throughout, worked examples of field sketches and illustrations are provided as well as descriptions of the common mistakes to be avoided.


2020 ◽  
Vol 12 (05) ◽  
pp. 2050051
Author(s):  
Khawla Essassi ◽  
Jean-Luc Rebiere ◽  
Abderrahim El Mahi ◽  
Mohamed Amine Ben Souf ◽  
Anas Bouguecha ◽  
...  

In this research contribution, the static behavior and failure mechanisms are developed for a three-dimensional (3D) printed dogbone, auxetic structure and sandwich composite using acoustic emissions (AEs). The skins, core and whole sandwich are manufactured using the same bio-based material which is polylactic acid reinforced with micro-flax fibers. Tensile tests are conducted on the skins and the core while bending tests are conducted on the sandwich composite. Those tests are carried out on four different auxetic densities in order to investigate their effect on the mechanical and damage properties of the materials. To monitor the invisible damage and damage propagation, a highly sensitive AE testing method is used. It is found that the sandwich with high core density displays advanced mechanical properties in terms of bending stiffness, shear stiffness, facing bending stress and core shear stress. In addition, the AE data points during testing present an amplitude range of 40–85[Formula: see text]dB that characterizes visible and invisible damage up to failure.


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