scholarly journals Scientific Experimental Data Representation Standard through Knowledge Metadata Representation Model

2019 ◽  
Vol 18 (02) ◽  
pp. 1950022
Author(s):  
Nur Adila Azram ◽  
Rodziah Atan

The growth of data from scientific experiments is increasing nowadays. These data came from different experiments done through various laboratory instruments or machines. It became an issue to manage and analyse scientific experimental data because of the heterogeneous nature of data structure and format. This paper proposed a knowledge metadata representation model to standardise the scientific experimental data representation to make it a standard structure. We discussed the methodology of the proposed model and gives the analysis of results. The evaluation and validation of the knowledge metadata representation model, as well as the verification of the metadata elements extraction, show promising results.

Personalized medicine exploits the patient data, for example, genetic compositions, and key biomarkers. During the data mining process, the key challenges are the information loss, the data types heterogeneity and the time series representation. In this paper, a novel data representation model for personalized medicine is proposed in light of these challenges. The proposed model will account for the structured, temporal and non-temporal data and their types, namely, numeric, nominal, date, and Boolean. After the "Date and Boolean" data transformation, the nominal data are treated by dispersion while several clustering techniques are deployed to control the numeric data distribution. Ultimately, the transformation process results in three homogeneous representations with these representations having only two dimensions to ease the exploration of the represented dataset. Compared to the Symbolic Aggregate Approximation technique, the proposed model preserves the time-series information, conserves as much data as possible and offers multiple simple representations to be explored.


2020 ◽  
Vol 17 (6) ◽  
pp. 511-522 ◽  
Author(s):  
Alicia Graciela Cid ◽  
María Verónica Ramírez-Rigo ◽  
María Celeste Palena ◽  
Elio Emilio Gonzo ◽  
Alvaro Federico Jimenez-Kairuz ◽  
...  

Background: Mathematical modeling in modified drug release is an important tool that allows predicting the release rate of drugs in their surrounding environment and elucidates the transport mechanisms involved in the process. Objective: The aim of this work was to develop a mathematical model that allows evaluating the release profile of drugs from polymeric carriers in which the swelling phenomenon is present. Methods: Swellable matrices based on ionic complexes of alginic acid or carboxymethylcellulose with ciprofloxacin were prepared and the effect of adding the polymer sodium salt on the swelling process and the drug release was evaluated. Experimental data from the ciprofloxacin release profiles were mathematically adjusted, considering the mechanisms involved in each stage of the release process. Results: A proposed model, named “Dual Release” model, was able to properly fit the experimental data of matrices presenting the swelling phenomenon, characterized by an inflection point in their release profile. This entails applying the extended model of Korsmeyer-Peppas to estimate the percentage of drug released from the first experimental point up to the inflection point and then a model called Lumped until the final time, allowing to adequately represent the complete range of the drug release profile. Different parameters of pharmaceutical relevance were calculated using the proposed model to compare the profiles of the studied matrices. Conclusion: The “Dual Release” model proposed in this article can be used to predict the behavior of complex systems in which different mechanisms are involved in the release process.


2021 ◽  
Vol 11 (2) ◽  
Author(s):  
María Jiménez-Buedo

AbstractReactivity, or the phenomenon by which subjects tend to modify their behavior in virtue of their being studied upon, is often cited as one of the most important difficulties involved in social scientific experiments, and yet, there is to date a persistent conceptual muddle when dealing with the many dimensions of reactivity. This paper offers a conceptual framework for reactivity that draws on an interventionist approach to causality. The framework allows us to offer an unambiguous definition of reactivity and distinguishes it from placebo effects. Further, it allows us to distinguish between benign and malignant forms of the phenomenon, depending on whether reactivity constitutes a danger to the validity of the causal inferences drawn from experimental data.


Author(s):  
Adam Barylski ◽  
Mariusz Deja

Silicon wafers are the most widely used substrates for fabricating integrated circuits. A sequence of processes is needed to turn a silicon ingot into silicon wafers. One of the processes is flattening by lapping or by grinding to achieve a high degree of flatness and parallelism of the wafer [1, 2, 3]. Lapping can effectively remove or reduce the waviness induced by preceding operations [2, 4]. The main aim of this paper is to compare the simulation results with lapping experimental data obtained from the Polish producer of silicon wafers, the company Cemat Silicon from Warsaw (www.cematsil.com). Proposed model is going to be implemented by this company for the tool wear prediction. Proposed model can be applied for lapping or grinding with single or double-disc lapping kinematics [5, 6, 7]. Geometrical and kinematical relations with the simulations are presented in the work. Generated results for given workpiece diameter and for different kinematical parameters are studied using models programmed in the Matlab environment.


Author(s):  
Fakhreddine Landolsi ◽  
Fathi H. Ghorbel ◽  
James B. Dabney

AFM-based nanomanipulation is very challenging because of the complex mechanics in tip-sample interactions and the limitations in AFM visual sensing capabilities. In the present paper, we investigate the modeling of AFM-based nanomanipulation emphasizing the effects of the relevant interactions at the nanoscale. The major contribution of the present work is the use of a combined DMT-JKR interaction model in order to describe the complete collision process between the AFM tip and the sample. The coupling between the interactions and the friction at the nanoscale is emphasized. The efficacy of the proposed model to reproduce experimental data is demonstrated via numerical simulations.


2020 ◽  
pp. 93-98
Author(s):  
Viktar V. Tur ◽  
Radoslaw Duda ◽  
Dina Khmaruk ◽  
Viktar Basav

In this paper, a modified strains development model (MSDM) for expansive concrete-filled steel tube (ECFST) was formulated and verified on the experimental data, obtained from testing specimens on the expansion stage. The modified strain development model for restraint strains and self-stresses values estimation in concrete with high expansion energy capacity under any type of the symmetrical and unsymmetrical finite stiffness restraint conditions was proposed. Based on proposed MSDM a new model for expansive concrete-filled steel tubes is developed. The main difference between this model and other previously developed models consists in taking into account in the basic equations an induced force in restrain that is considered as an external load applied to the concrete core of the member. For verification of the proposed model-specific experimental studies were performed. As follows from comparison results restrained expansion strains values calculated following the proposed model shows good compliance with experimental data. The values predicted by the proposed MSDM for concrete-filled steel and obtained experimental data demonstrated good agreement that confirms the validity of the former.


2020 ◽  
Vol 9 (9) ◽  
pp. e49996648
Author(s):  
David da Silva Vasconcelos ◽  
Sirlene Barbosa Lima ◽  
Ana Cristina Morais da Silva ◽  
José Mário Ferreira Júnior ◽  
Carlos Augusto de Moraes Pires

In a previous study, a statistical model was developed using the experimental planning technique for evaluating the influence of its variables on fluidization velocity. In this study, we investigated the Vasconcelos-statistical model (VSM) in data representation, considering fluidization with and without segregation. The methodology used was based on the simulation of the fluidization velocity of nine binary systems, comprising sand, and eight biomasses published by six authors. In addition, the results obtained using VSM were compared with those obtained using five other models, reported by different authors, but adjusted to the experimental data of these biomasses. The result obtained by the proposed models mainly indicated a discrepancy between the experimental and calculated fluidization velocities. VSM, using only three variables (particle size, particle diameter, and biomass mass fraction), yielded results of smaller discrepancy values in all simulations (2.23–12.51%), as opposed to the other comparative models, which presented more significant numbers of variables. Thus, VSM is defined as one of the most interesting models for predicting the fluidization velocity of several biomasses.


2005 ◽  
Vol 480-481 ◽  
pp. 197-200
Author(s):  
Y. Sayad ◽  
A. Nouiri

An increasing of donor centres has been detected in n-InSb when it was submitted to anneal/quench with various annealing temperature (450 °C - 850 °C) and various annealing time (5 - 100 hours). A theoretical study of the kinetics of the conduction conversion of n-InSb at temperature annealing above 250 °C has been made. The present analysis indicates that the donor concentration increases with increasing of annealing time. In order to study this variation and to give a model for donor centres generated, a proposed model based on the simple kinetic is used to fit the variation of donor concentration as a function of annealing time. However, from the best fit of experimental data using the proposed model, the activation energy is determined.


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