Antimicrobial photodynamic therapy against Staphylococcus aureus using zinc phthalocyanine and zinc phthalocyanine-integrated TiO2 nanoparticles

2019 ◽  
Vol 23 (01n02) ◽  
pp. 206-212 ◽  
Author(s):  
Ayça Tunçel ◽  
İsmail Öztürk ◽  
Mine Ince ◽  
Kasim Ocakoglu ◽  
Mine Hoşgör-Limoncu ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Antibiotic Resistance ◽  
Photodynamic Therapy ◽  
Minimum Inhibitory Concentration ◽  
Inhibitory Concentration ◽  
Light Emitting Diode ◽  
High Light ◽  
Zinc Phthalocyanine ◽  
Antimicrobial Photodynamic Therapy ◽  
Light Emitting

Antibiotic resistance is an increasing healthcare problem worldwide. In the present study, the effects of antimicrobial photodynamic therapy (APDT) of ZnPc and ZnPc-integrated TiO2 nanoparticles (ZnPc-TiO[Formula: see text] were investigated against Staphylococcus aureus. A light emitting diode (LED) (630–700 nm, 17.4 mW/cm[Formula: see text] was used on S. aureus at different light doses (8 J/cm2 for 11 min, 16 J/cm2 for 22 min, 24 J/cm2 for 33 min) in the presence of the compounds under the minimum inhibitory concentration values. Both compounds showed similar phototoxicity toward S. aureus when high light doses (16 and 24 J/cm[Formula: see text] were applied. In addition, the success of APDT increased with an increasing light dose.

scholarly journals Application of Teeth Whitening LED for Prevention of Dental Caries : Antimicrobial Photodynamic Therapy Approach

2020 ◽  
Vol 47 (1) ◽  
pp. 70-77
Author(s):  
Choa Park ◽  
Howon Park ◽  
Juhyun Lee ◽  
Hyunwoo Seo ◽  
Siyoung Lee
Keyword(s):  
Photodynamic Therapy ◽  
Laser Scanning ◽  
Light Emitting Diode ◽  
Antimicrobial Effect ◽  
Laser Scanning Microscopy ◽  
Confocal Laser ◽  
Control Group ◽  
Antimicrobial Photodynamic Therapy ◽  
Group Dynamic ◽  
Light Emitting

The present study is aimed to assess the effect of antimicrobial photodynamic therapy (aPDT) on <i>Streptococcus mutans</i> biofilm through teeth whitening light emitting diode (LED).<br/>Planktonic and dynamic biofilm state cultures of <i>S. mutans</i> were used. Erythrosine 20 μM/L was used as the photosensitizer. Irradiation was performed by exposing cultures to clinic and homecare whitening LEDs for 15 minutes. The viability was measured through Colony Forming Unit counts and confocal laser scanning microscopy.<br/>aPDT using whitening LEDs and erythrosine significantly decreased the CFU count of <i>S. mutans</i> compared to that in the control group. Dynamic biofilm group showed more resistant features to aPDT compared with planktonic state. Clinic and homecare whitening LED device showed similar antimicrobial effect.<br/>The whitening LED, which could irradiate the entire oral arch, showed a significant photodynamic effect on cariogenic <i>S. mutans</i> biofilm. aPDT mediated by erythrosine and LEDs used for teeth whitening exhibited promising antimicrobial activity.

Organic Light Emitting Diode for in vitro Antimicrobial Photodynamic Therapy of Candida Strains

2021 ◽  
pp. 102567
Author(s):  
Uriel Melendez-Celis ◽  
Teresita Spezzia-Mazzocco ◽  
Saydulla Persheyev ◽  
Cheng Lian ◽  
Ifor Samuel ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Light Emitting Diode ◽  
Antimicrobial Photodynamic Therapy ◽  
Light Emitting ◽  
Organic Light Emitting Diode ◽  
Organic Light
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