A Comparative Study of the Inhibitory Effects of Rheum palmatum L. and Isatis Indigotica Root, on 3CLpro from SARS-CoV-2 Using Both Cell-based and Cell-free Assay Models

2021 ◽  
Author(s):  
Yuhao Lan
Keyword(s):  
Comparative Study ◽  
Inhibitory Effects ◽  
Isatis Indigotica ◽  
Rheum Palmatum

scholarly journals The inhibition of deoxyribonucleic acid nucleotidyltransferase by stilboestrol derivatives

1968 ◽  
Vol 108 (5) ◽  
pp. 749-753 ◽  
Author(s):  
A R Fahmy ◽  
K Griffiths
Keyword(s):  
Comparative Study ◽  
Deoxyribonucleic Acid ◽  
Inhibitory Effect ◽  
Effective Inhibitor ◽  
Inhibitory Effects ◽  
Alkyl Substitution ◽  
Competitive Kinetics ◽  
Calf Thymus

The inhibition by diethylstilboestrol of DNA nucleotidyltransferase isolated from calf thymus was studied. The inhibition exercised by diethylstilboestrol appears to obey competitive kinetics with respect to DNA primer. The activities of both replicative and terminal enzymes were affected to the same extent. There was no evidence of binding between DNA and diethylstilboestrol. A comparative study of the inhibitory effects of some stilboestrol derivatives is presented. The alkyl substitution in the αα′-positions seem to alter the inhibitory effect of these compounds: dimethylstilboestrol was more inhibitory than stilbene, and diethylstilboestrol was more inhibitory than dimethylstilboestrol. Hexoestrol, in which the αα′-ethylenic linkage is saturated, was the most effective inhibitor.

A Comparative Study on the Inhibitory Effects of Different Parts and Chemical Constituents of Pomegranate on α-Amylase and α-Glucosidase

2012 ◽  
Vol 27 (11) ◽  
pp. 1614-1620 ◽  
Author(s):  
Antony Kam ◽  
Kong M. Li ◽  
Valentina Razmovski-Naumovski ◽  
Srinivas Nammi ◽  
Jeffrey Shi ◽  
...  
Keyword(s):  
Comparative Study ◽  
Chemical Constituents ◽  
Inhibitory Effects ◽  
Different Parts

Protective and Inhibitory Effects of Various Types of Amphipols on the Ca2+-ATPase from Sarcoplasmic Reticulum:  A Comparative Study†

Biochemistry ◽  
2006 ◽  
Vol 45 (6) ◽  
pp. 1861-1869 ◽  
Author(s):  
Martin Picard ◽  
Tassadite Dahmane ◽  
Manuel Garrigos ◽  
Carole Gauron ◽  
Fabrice Giusti ◽  
...  
Keyword(s):  
Sarcoplasmic Reticulum ◽  
Comparative Study ◽  
Inhibitory Effects
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