Measurement of ‘Basal’ and Total Metabolism in Hereditarily Obese-Hyperglycemic Mice

1958 ◽  
Vol 193 (3) ◽  
pp. 495-498 ◽  
Author(s):  
Ruth McClintock ◽  
Nathan Lifson
Keyword(s):  
Carbon Dioxide ◽  
Oxygen Consumption ◽  
Energy Expenditure ◽  
Voluntary Movement ◽  
Carbon Dioxide Production ◽  
Open Circuit ◽  
Energy Output ◽  
Obese Mice ◽  
Energy Expenditures ◽  
Isotope Method

Measurements of oxygen consumption and carbon dioxide production were made by the Haldane open circuit method on hereditarily obese mice and littermate controls, and the energy expenditures were estimated. Studies were made on mice for short periods under ‘basal’ conditions, and for periods of approximately a day with the mice fasted and confined, fasted and relatively unconfined, and fed and unconfined. The total energy expenditures of fed and unconfined obese mice were found to be higher than those of nonobese littermate controls by virtue of a) increased ‘basal metabolism’, b) greater energy expenditure associated with feeding, and possibly c) larger energy output for activity despite reduced voluntary movement. The values obtained for total metabolism confirm those previously determined by an isotope method for measuring CO2 output.

GASEOUS METABOLISM IN PREMATURE INFANTS AT 32-34°C AMBIENT TEMPERATURE

PEDIATRICS ◽  
1964 ◽  
Vol 33 (1) ◽  
pp. 75-82
Author(s):  
Forrest H. Adams ◽  
Tetsuro Fujiwara ◽  
Robert Spears ◽  
Joan Hodgman
Keyword(s):  
Carbon Dioxide ◽  
Oxygen Consumption ◽  
Premature Infants ◽  
Rectal Temperature ◽  
Respiratory Quotient ◽  
Carbon Dioxide Production ◽  
Open Circuit ◽  
Co2 Production ◽  
O2 Consumption ◽  
Rate Of Increase

Thirty-four measurements of oxygen consumption, carbon dioxide production, respiratory quotient, and rectal temperature were made on 22 premature infants with ages ranging from 2½ hours to 18 days. The studies were conducted at 32-34°C utilizing an open circuit apparatus and a specially designed climatized chamber. Oxygen consumption and carbon dioxide production were lowest in the first 12 hours and increased thereafter. The rate of increase in O2 consumption was greater than that of CO2 production, with a consequent fall in respiratory quotient during the first 76 hours of life. A reverse relation of O2 consumption and CO2 production was found following the 4th day of life with a consequent rise in respiratory quotient. There was a close correlation between O2 consumption and rectal temperature regardless of age. A respiratory quotient below the value of 0.707 for fat metabolism was observed in 7 premature infants with ages ranging from 24 to 76 hours.

Combined heart rate and activity improve estimates of oxygen consumption and carbon dioxide production rates

1996 ◽  
Vol 81 (4) ◽  
pp. 1754-1761 ◽  
Author(s):  
Jon K. Moon ◽  
Nancy F. Butte
Keyword(s):  
Carbon Dioxide ◽  
Heart Rate ◽  
Oxygen Consumption ◽  
Energy Expenditure ◽  
Carbon Dioxide Production ◽  
Alternative Methods ◽  
Prediction Errors ◽  
Nonlinear Functions ◽  
Production Rates ◽  
Basal Energy Expenditure

Moon, Jon K., and Nancy F. Butte. Combined heart rate and activity improve estimates of oxygen consumption and carbon dioxide production rates. J. Appl. Physiol.81(4): 1754–1761, 1996.—Oxygen consumption (V˙o 2) and carbon dioxide production (V˙co 2) rates were measured by electronically recording heart rate (HR) and physical activity (PA). Mean daily V˙o 2 andV˙co 2 measurements by HR and PA were validated in adults ( n = 10 women and 10 men) with room calorimeters. Thirteen linear and nonlinear functions of HR alone and HR combined with PA were tested as models of 24-h V˙o 2 andV˙co 2. Mean sleepV˙o 2 andV˙co 2 were similar to basal metabolic rates and were accurately estimated from HR alone [respective mean errors were −0.2 ± 0.8 (SD) and −0.4 ± 0.6%]. The range of prediction errors for 24-h V˙o 2 andV˙co 2 was smallest for a model that used PA to assign HR for each minute to separate active and inactive curves (V˙o 2, −3.3 ± 3.5%; V˙co 2, −4.6 ± 3%). There were no significant correlations betweenV˙o 2 orV˙co 2 errors and subject age, weight, fat mass, ratio of daily to basal energy expenditure rate, or fitness. V˙o 2,V˙co 2, and energy expenditure recorded for 3 free-living days were 5.6 ± 0.9 ml ⋅ min−1 ⋅ kg−1, 4.7 ± 0.8 ml ⋅ min−1 ⋅ kg−1, and 7.8 ± 1.6 kJ/min, respectively. Combined HR and PA measured 24-h V˙o 2 andV˙co 2 with a precision similar to alternative methods.

scholarly journals The respiratory quotient in the newborn pig

1969 ◽  
Vol 23 (2) ◽  
pp. 407-413 ◽  
Author(s):  
L. E. Mount
Keyword(s):  
Carbon Dioxide ◽  
Oxygen Consumption ◽  
Energy Metabolism ◽  
Respiratory Quotient ◽  
Carbon Dioxide Production ◽  
Mean Value ◽  
Open Circuit ◽  
Mean Values ◽  
The Mean ◽  
Environmental Temperatures

1. Rates of oxygen consumption and carbon dioxide production were measured in pigs from birth to 3 days of age in an open-circuit system.2. The mean respiratory quotient (RQ) during the first 6 h following birth was 0.95 in fasted pigs and 0.91 in pigs which were allowed to feed.3. The RQ fell during the remainder of the first postnatal day to mean values close to 0.85, whether the pigs were allowed to feed from birth or were fasted.4. From 1 to 3 days of age the RQ had a mean value of 0.79.5. There was little difference in the RQ of pigs exposed to environmental temperatures of either 32 or 16°.6. It is concluded that the baby pig is not exclusively dependent on carbohydrate for its energy metabolism.

scholarly journals Calculating metabolic energy expenditure across a wide range of exercise intensities: the equation matters

2018 ◽  
Vol 43 (6) ◽  
pp. 639-642 ◽  
Author(s):  
Shalaya Kipp ◽  
William C. Byrnes ◽  
Rodger Kram
Keyword(s):  
Carbon Dioxide ◽  
Oxygen Consumption ◽  
Energy Expenditure ◽  
Metabolic Rate ◽  
Carbon Dioxide Production ◽  
Metabolic Energy ◽  
Distance Runners ◽  
Wide Range ◽  
Using Data ◽  
Metabolic Energy Expenditure

We compared 10 published equations for calculating energy expenditure from oxygen consumption and carbon dioxide production using data for 10 high-caliber male distance runners over a wide range of running velocities. We found up to a 5.2% difference in calculated metabolic rate between 2 widely used equations. We urge our fellow researchers abandon out-of-date equations with published acknowledgments of errors or inappropriate biochemical/physical assumptions.

Effects of Varied Vocal Intensity on Ventilation and Energy Expenditure in Women and Men

1998 ◽  
Vol 41 (2) ◽  
pp. 239-248 ◽  
Author(s):  
Bridget A. Russell ◽  
Frank J. Cerny ◽  
Elaine T. Stathopoulos
Keyword(s):  
Carbon Dioxide ◽  
Steady State ◽  
Energy Expenditure ◽  
Minute Ventilation ◽  
Face Mask ◽  
Carbon Dioxide Production ◽  
Quiet Breathing ◽  
Energy Expenditures ◽  
Ventilatory Responses ◽  
End Tidal

This study was completed to determine how ventilatory responses change by means of speech reading at three different sound pressure levels (SPL) as compared to quiet breathing prior to each task. The energy required to alter SPL was also studied and compared to energy expenditures during a quiet breathing condition. Twenty-four adults (12 women, 12 men) were studied while reading a standard passage at low, comfortable, and high SPLs for 7 minutes with quiet breathing periods between each task to achieve respiratory steady state and serve as a control to which the reading tasks were compared. The last 2 minutes of exhaled air for all speaking and quiet breathing tasks were collected using a Hans Rudolph mouth breathing face mask. A Sensor Medics V max 29 TM series diagnostic instrument system measured all ventilatory responses and energy expenditures. Volume and timing alterations in ventilation were characterized by measuring tidal volume (V T ), inspiratory time (T I ), inspiratory flow rate (V T /T I ), and expiratory time (T E ). Average ventilation, energy expenditure, and adequacy of ventilation were measured using minute ventilation (V W E ), oxygen consumption V W O 2 ), carbon dioxide production (V W CO 2 ), and partial pressure of end-tidal carbon dioxide (end-tidal PET CO2 ). Results indicated volume, timing, ventilation, and energy expenditure values remained closest to quiet breathing values for the comfortable SPL. Volume, ventilation, and energy expenditure were significantly greater for the high SPL and lower for the low SPL, compared to the baseline steady state, indicating that the low SPL causes a ventilatory deficit that was found to be paid back at the end of the speech task during the quiet breathing period. These results demonstrate that an individual's comfortable SPL is the least energyrequiring way to speech breathe. As SPL rises above or below comfortable SPL, speech breathing requires more energy.

scholarly journals The Accuracy and Precision of an Open-Circuit System To Measure Oxygen Consumption and Carbon Dioxide Production in Neonates

1987 ◽  
Vol 21 (1) ◽  
pp. 58-65 ◽  
Author(s):  
Keith H Marks ◽  
Patricia Coen ◽  
James R Kerrigan ◽  
Nick A Francalancia ◽  
Elizabeth E Nardis ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Oxygen Consumption ◽  
Carbon Dioxide Production ◽  
Open Circuit ◽  
Accuracy And Precision ◽  
Measure Oxygen Consumption
Sign in / Sign up

Export Citation Format

Share Document