Revisiting the evaluation of central versus peripheral thermoregulatory control in humans

Author(s):  
Nicholas Ravanelli ◽  
Philippe Gendron ◽  
Daniel Gagnon

Human thermoregulatory control is often evaluated through the relationship between thermoeffector output and core or mean body temperature. In addition to providing a general indication of whether a variable of interest alters thermoregulatory control, this relationship is often used to determine how this alteration may occur. This latter interpretation relies upon two parameters of the thermoeffector output-body temperature relationship; the onset threshold and thermosensitivity. Traditionally, changes in the onset threshold and thermosensitivity are interpreted as "central" or "peripheral" modulation of thermoregulatory control, respectively. This mini-review revisits the origins of the thermoeffector output-body temperature relationship and its use to interpret "central" or "peripheral" modulation of thermoregulatory control. Against this background, we discuss the strengths and weaknesses of this approach and highlight that "central" thermoregulatory control reflects the neural control of body temperature whereas "peripheral" thermoregulatory control reflects properties specific to the thermoeffector organs. We highlight studies that employed more direct approaches to investigate the neural control of body temperature and peripheral properties of thermoeffector organs. We conclude by encouraging future investigations interested in studying thermoregulatory control to more directly investigate the component of the thermoeffector loop under investigation.

2012 ◽  
Vol 36 (1) ◽  
pp. 8-14
Author(s):  
Al-Shawi A.F. S.

The relationship between the clinical singes and some of the hematological and biochemical values in 126 cases of local breed and Shammi breed goats (from both sexes) diagnosed as cases of malnutrition from 230 goats examined .The clinical examination include (beside the general inspection and case history) body temperature, respiratory and pulse rates, mucus membranes skin and coat. Examination of the blood samples included RBCs count, Hb concentration, PCV % and values of cupper, magnesium, phosphorus, and potassium. The results showed that the mean body temperature of these goats was lower than in normal goats, while the respiratory and pulse rates were higher .Examination of blood revealed decrease in the means of RBCs counts ,Hb concentration and PCV % in the clinically diagnosed cases , and the decrease was more sever in local goats . However the results indicated lower values of cupper, magnesium, phosphorus, and potassium in comparison with normal values in goats. The ratio of cupper deficiency was the highest followed by phosphorus, magnesium and potassium and the ratio of malnutrition was high in Baghdad province. It was in Shammi breed higher than in local breed.


2012 ◽  
Vol 36 (1) ◽  
pp. 8-14
Author(s):  
Al-Shawi A.F. S.

The relationship between the clinical singes and some of the hematological and biochemical values in 126 cases of local breed and Shammi breed goats (from both sexes) diagnosed as cases of malnutrition from 230 goats examined .The clinical examination include (beside the general inspection and case history) body temperature, respiratory and pulse rates, mucus membranes skin and coat. Examination of the blood samples included RBCs count, Hb concentration, PCV % and values of cupper, magnesium, phosphorus, and potassium. The results showed that the mean body temperature of these goats was lower than in normal goats, while the respiratory and pulse rates were higher .Examination of blood revealed decrease in the means of RBCs counts ,Hb concentration and PCV % in the clinically diagnosed cases , and the decrease was more sever in local goats . However the results indicated lower values of cupper, magnesium, phosphorus, and potassium in comparison with normal values in goats. The ratio of cupper deficiency was the highest followed by phosphorus, magnesium and potassium and the ratio of malnutrition was high in Baghdad province. It was in Shammi breed higher than in local breed.


2021 ◽  
Vol 8 ◽  
Author(s):  
Fei Xu ◽  
Cheng Zhang ◽  
Chao Liu ◽  
Siwei Bi ◽  
Jun Gu

Background: This study was aimed to investigate the relationship between first 24-h mean body temperature and clinical outcomes of post cardiac surgery patients admitted to intensive care unit (ICU) in a large public clinical database.Methods: This is a retrospectively observational research of MIMIC III dataset, a total of 6,122 patients included. Patients were divided into 3 groups according to the distribution of body temperature. Multivariate cox analysis and logistic regression analysis were used to investigate the association between abnormal temperature, and clinical outcomes.Results: Hypothermia (<36°C) significantly associated with increasing in-hospital mortality (HR 1.665, 95%CI 1.218–2.276; p = 0.001), 1-year mortality (HR 1.537, 95% CI 1.205–1.961; p = 0.001), 28-day mortality (HR 1.518, 95% CI 1.14–2.021; p = 0.004), and 90-day mortality (HR 1.491, 95% CI 1.144–1.943; p = 0.003). No statistical differences were observed between short-term or long-term mortality and hyperthermia (>38°C). Hyperthermia was related to the extended length of ICU stay (p < 0.001), and hospital stay (p < 0.001).Conclusion: Hypothermia within 24h after ICU admission was associated with the increased mortality of post cardiac surgery patients. Enhanced monitoring of body temperature within 24h after cardiac surgery should be taken into account for improving clinical outcomes.


2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Ali Dinc ◽  
Yousef Gharbia

Abstract In this study, exergy efficiency calculations of a turboprop engine were performed together with main performance parameters such as shaft power, specific fuel consumption, fuel flow, thermal efficiency etc., for a range of flight altitude (0–14 km) and flight speeds (0–0.6 Mach). A novel exergy efficiency formula was derived in terms of specific fuel consumption and it is shown that these two parameters are inversely proportional to each other. Moreover, a novel exergy efficiency and thermal efficiency relation was also derived. The relationship showed that these two parameters are linearly proportional to each other. Exergy efficiency of the turboprop engine was found to be in the range of 23–33%. Thermal efficiency of the turboprop engine was found to be around 25–35%. Exergy efficiency is higher at higher speeds and altitude where the specific fuel consumption is lower. Conversely, exergy efficiency of the engine is lower for lower speeds and altitude where the specific fuel consumption is higher.


SLEEP ◽  
2021 ◽  
Author(s):  
Yi-Ge Huang ◽  
Sarah J Flaherty ◽  
Carina A Pothecary ◽  
Russell G Foster ◽  
Stuart N Peirson ◽  
...  

Abstract Study objectives Torpor is a regulated and reversible state of metabolic suppression used by many mammalian species to conserve energy. Whereas the relationship between torpor and sleep has been well-studied in seasonal hibernators, less is known about the effects of fasting-induced torpor on states of vigilance and brain activity in laboratory mice. Methods Continuous monitoring of electroencephalogram (EEG), electromyogram (EMG) and surface body temperature was undertaken in adult, male C57BL/6 mice over consecutive days of scheduled restricted feeding. Results All animals showed bouts of hypothermia that became progressively deeper and longer as fasting progressed. EEG and EMG were markedly affected by hypothermia, although the typical electrophysiological signatures of NREM sleep, REM sleep and wakefulness enabled us to perform vigilance-state classification in all cases. Consistent with previous studies, hypothermic bouts were initiated from a state indistinguishable from NREM sleep, with EEG power decreasing gradually in parallel with decreasing surface body temperature. During deep hypothermia, REM sleep was largely abolished, and we observed shivering-associated intense bursts of muscle activity. Conclusions Our study highlights important similarities between EEG signatures of fasting-induced torpor in mice, daily torpor in Djungarian hamsters and hibernation in seasonally-hibernating species. Future studies are necessary to clarify the effects on fasting-induced torpor on subsequent sleep.


2019 ◽  
Vol 60 (5) ◽  
pp. 1037-1048
Author(s):  
Hussein Ilaibi Zamil Al-Sudani

     In any natural area or water body, evapotranspiration is one of the important outcomes in the water balance equation. As a significant method and depending on monthly average temperature, estimating of potential Evapotranspiration depending on Thornthwaite method was adopted in this research review. Estimate and discuss evapotranspiration by using Thornthwaite method is the main objectives of this research review with considerable details as well as compute potential evapotranspiration based on climatologically data obtained in Iraq. Temperature - evapotranspiration relationship can be estimated between those two parameters to reduce cost and time and facilitate calculation of water balance in lakes, river, and hydrogeological basins. The relationship was obtained using Thornthwaite method in Iraq by dividing the area into seven sectors according to geographic latitude. Each sector has multi meteorological stations where thirty two stations were used with different periods of records. A mathematical relationship was obtained between mean temperature and corrected potential evapotranspiration with (97.45) to (99.84) coefficient of determination. The mean temperature has a decreasing pattern from southern east towards northern west of Iraq affected by Mediterranean Sea climate conditions, while corrected potential evapotranspiration has the opposite direction regarding increased value because of a direct relationship with temperature.


1973 ◽  
Vol 95 (2) ◽  
pp. 236-241
Author(s):  
T. F. Ford ◽  
C. R. Singleterry

Many relationships between viscosity or its reciprocal, fluidity, and temperature have been proposed for liquids. None except the empirically modified ASTM chart have proven satisfactory over extended temperature ranges. We here note that by plotting the kinematic fluidity (φkin) against the square of the absolute temperature (deg K2) we obtain linear relationships for a wide variety of organic liquids at kinematic viscosities less than about 1.67 centistokes (or fluidities above about 0.60 reciprocal centistokes). The generality of the relationship appears to justify the use of the equation, φkin=a+bT2, as an interpolation formula for organic liquids in the low viscosity region.


2020 ◽  
Author(s):  
Zhongwen Jin ◽  
Yuwei Meng ◽  
Rongdong Yu ◽  
Ruochen Huang ◽  
Mingyang Lu ◽  
...  

<p>Previously, a conductivity invariance phenomena (CIP) has been discovered – at a certain lift-off, the inductance change of the sensor due to a test sample is immune to conductivity variations, i.e. the inductance – lift-off curve passes through a common point at a certain lift-off, termed as conductivity invariance lift-off. However, this conductivity invariance lift-off is fixed for a particular sensor setup, which is not convenient for various sample conditions. In this paper, we propose using two parameters in the coil design – the horizontal and vertical distances between the transmitter and the receiver to control the conductivity invariance lift-off. The relationship between these two parameters and the conductivity invariance lift-off is investigated by simulation and experiments and it has been found that there is an approximate linear relationship between these two parameters and the conductivity invariance lift-off. This is useful for applications where the measurements have restrictions on lift-off, e.g. uneven coating thickness which limits the range of the lift-off of probe during the measurements. Therefore, based on this relationship, it can be easier to adjust the configuration of the probe for a better inspection of the test samples.</p>


Author(s):  
W.B.P.N. Herath ◽  
R.A.K.I. Ranasinghe ◽  
M.P.C. Sandaru ◽  
I.A.S. Lakmali ◽  
A.G.N.K. Aluthgama ◽  
...  

Addressing the emotional and mental health of the bedridden elderly is necessary as they are more likely to be depressed being isolated and dependent on a caregiver for a prolonged time. Several studies have been carried out to identify the mental stress of patients through their skin conductivity. The variations in the sympathetic nervous system reflect the emotional state of a person. This is demonstrated by the Galvanic Skin Response and thus can be used as a denotation of psychological or physiological arousal. Such arousal causes the blood capillary dilation, increment of sweat gland activities making the skin further conductive to electricity. In this study we develop a sensor module composed of a Galvanic Skin Response sensor for the bed ridden elderly and identify the relationship between body temperature, heart rate and GSR of them. The experiment is conducted upon 10 bed ridden elderly aged from 60 – 80 years of the Mihinthale region. The observations demonstrate a correlation between the heart rate, body temperature, skin conductivity and the human physiological states.


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