Physiological effects of hydrogen sulfide inhalation during exercise in healthy men

1991 ◽  
Vol 71 (5) ◽  
pp. 1872-1877 ◽  
Author(s):  
Y. Bhambhani ◽  
M. Singh

Occupational exposure to hydrogen sulfide (H2S) is prevalent in a variety of industries. H2S when inhaled 1) is oxidized into a sulfate or a thiosulfate by oxygen bound to hemoglobin and 2) suppresses aerobic metabolism by inhibiting cytochrome oxidase (c and aa3) activity in the electron transport chain. The purpose of this study was to examine the acute effects of oral inhalation of H2S on the physiological responses during graded cycle exercise performed to exhaustion in healthy male subjects. Sixteen volunteers were randomly exposed to 0 (control), 0.5, 2.0, and 5.0 ppm H2S on four separate occasions. Compared with the control values, the results indicated that the heart rate and expired ventilation were unaffected as a result of the H2S exposures during submaximal and maximal exercise. The oxygen uptake had a tendency to increase, whereas carbon dioxide output had a tendency to decrease as a result of the H2S exposures, but only the 5.0 ppm exposure resulted in a significantly higher maximum oxygen uptake. Blood lactate concentrations increased significantly during submaximal and maximal exercise as a result of the 5.0 ppm exposure. Despite these large increases in lactate concentration, the maximal power output of the subjects was not significantly altered as a result of the 5.0 ppm H2S exposure. It was concluded that healthy young male subjects could safely exercise at their maximum metabolic rates while breathing 5.0 ppm H2S without experiencing a significant reduction in their maximum physical work capacity during short-term incremental exercise.

1980 ◽  
Vol 48 (6) ◽  
pp. 1060-1064 ◽  
Author(s):  
R. M. Glaser ◽  
M. N. Sawka ◽  
M. F. Brune ◽  
S. W. Wilde

The purpose of this investigation was to compare physical work capacity (PWC), peak oxygen uptake (peak VO2), maximal pulmonary ventilation (VEmax), maximal heart rate (HRmax), and maximal blood lactate concentration (LAmax) for wheelchair ergometer (WERG) and arm crank ergometer (ACE) exercise. For this, wheelchair-dependent (n = 6) and able-bodied (n = 10) subjects completed a progressive intensity, discontinuous test for each mode of exercise. Each test was terminated by physical exhaustion and/or an inability to maintain a flywheel velocity of 180 m.min-1. Relatively high correlation coefficients were found between values obtained during the two modes of ergometry for PWC, peak VO2, VEmax, and HRmax. WERG exercise was found to elicit a significantly (P less than 0.05) lower PWC (by 36%), HRmax (by 7%), and LAmax (by 26%) than ACE exercise. Peak VO2 and VEmax, however, were similar for both exercise modes. These data suggest that either exercise mode may be used for fitness testing and training of people who cannot use their legs and that arm cranking may be a superior method to propel wheelchairs.


1987 ◽  
Vol 31 (12) ◽  
pp. 1331-1335
Author(s):  
Jeffrey E. Fernandez ◽  
Robert J. Marley ◽  
Nancy B. Stubbs

A laboratory experiment using 15 male subjects was conducted to document lifting physical work capacity over the frequency range of 2 to 12 lifts per minute and to compare these values to bicycling physical work capacity. Results indicate that bicycling PWC is significantly higher than lifting PWC at the 0.05 level. A variation in lifting PWC as a function of frequency was observed. This could be attributed to lifting technique. Task design should, therefore, not only consider lifting PWC but also the frequency of lift.


1965 ◽  
Vol 20 (2) ◽  
pp. 263-266 ◽  
Author(s):  
Ernest D. Michael ◽  
Steven M. Horvath

Maximal exercise tolerance tests were given to 30 female subjects 17-22 years old. The test consisted of exercising 1 min at a work load of 300 kpm/min and increasing the work load 150 kpm/min each minute until the subject could no longer exercise. The maximal heart rate level averaged 184 beat/min with a range between 170 and 202 beat/min. The average maximal Vo2 was 1.78 liter/min or 29.8 ml/kg per min. The submaximal ventilatory measurements were similar for all subjects while the heart rate levels at the submaximal work loads differentiated the subjects when grouped according to maximal work-load capacities. Prediction of maximal work capacity could not be made for individuals from any single submaximal measurement. There was .56 correlation between body weight and maximal work capacity with only a .32 relationship between maximal Vo2 and Vo2 per kilogram body weight. exercise tolerance of women; cardiorespiratory function of women during exercise; submaximal cardiorespiratory response; maximal cardiorespiratory measurements of women; response to maximal exercise; prediction of exercise tolerance Submitted on May 5, 1964


PEDIATRICS ◽  
1963 ◽  
Vol 32 (4) ◽  
pp. 742-756
Author(s):  
R. A. Bruce ◽  
J. R. Blackmon ◽  
J. W. Jones ◽  
G. Strait

1. Several approaches to assessment of physical work capacity in the upright posture in normal adults and cardiac patients have been reviewed critically. 2. Preliminary experience has been presented with a new multistage treadmill test of maximal exercise which permits appraisal of either a physically trained normal subject or an impaired but ambulatory cardiac patient. 3. The most effective means of differentiating cardiacs from normals has been an estimate of the total oxygen intake/Kg of body weight. 4. The need for monitoring the circulation with respect to arrhythmias, ischemia and/or hypotension has been emphasized. The authors wish to acknowledge their appreciation of many physicians, particularly Dr. Robert M. Levenson of the Seattle Cardiac Work Evaluation Clinic, and medical and graduate students who have assisted in the testing of patients and normals. The assistance of Mrs. Gladys Pettet is gratefully acknowledged also.


2018 ◽  
Vol 02 (04) ◽  
pp. E105-E112 ◽  
Author(s):  
Robert Nilsson ◽  
Ann-Sofie Lindberg ◽  
Apostolos Theos ◽  
Richard Ferguson ◽  
Christer Malm

AbstractThe aim of this study was to investigate the predictive power of aerobic test results and anthropometric variables on FIS-ranking of junior elite alpine skiers. Results from twenty-three male and female adolescent elite alpine skiers from two seasons were included in the multivariate statistical models. Physical work capacity was determined by V̇O2peak, blood lactate concentration ([HLa]b), and heart rate (HR) during ergometer cycling. Anthropometric variables were body stature, body weight and calculated BMI. No significant correlation between competitive performance and aerobic work capacity or anthropometric data was observed neither in male nor female adolescent skiers. Pre-season physical tests and anthropometric data could therefore not predict end-season FIS-ranking. The best regression (R2) and prediction (Q2) models of FIS slalom (SL) and giant slalom (GS) rank reached R2=0.51 to 0.86, Q2=−0.73 to 0.18, indicating no valid models. This study could not establish V̇O2peak and other included variables as predictors of competitive performance. When combining results from commonly used tests for alpine skiers, and applying multivariate statistical models, investigated tests seems of limited used for athletes, coaches, and ski federations. Performance-specific pre-season tests must be developed and validated for prediction of performance and guidance of exercise training.


1961 ◽  
Vol 16 (1) ◽  
pp. 153-156 ◽  
Author(s):  
Theodor Hettinger ◽  
Newton C. Birkhead ◽  
Steven M. Horvath ◽  
Bela Issekutz ◽  
Kaare Rodahl

Maximal oxygen uptakes were compared with the results from five different tests of physical work capacity in 96 men, 23–62 years of age. In addition, the 'predicted' maximal oxygen uptakes, according to the Ǻstrand-Ryhming nomogram, were compared with the actual measured maximal oxygen uptakes in the 28 subjects who were between 20 and 30 years of age. There was a statistically significant correlation between the maximal oxygen uptake and the following tests: the Harvard step test (P < .001); a new modified step test in which adjustments were made for the body weight and the length of the legs of the subject (P < .001); the Master step test (P < .05); and the Amplituden-Puls-Frequenz test, (P < .02). There was no statistically significant correlation between the maximal oxygen uptake and the Leistungs-Pulsindex. The correlation between the predicted maximal oxygen uptake and the measured maximal oxygen uptake was statistically significant at the .01 level. Submitted on May 16, 1960


2019 ◽  
Vol 7 (4) ◽  
pp. 12-18
Author(s):  
E.C. Freese ◽  
Kirk Cureton

Aim: Th e purpose of our study was to use a time-series design to investigate the eff ect of dietary quercetin supplementation on peak oxygen uptake (VO2peak) and physical work capacity. Methods and organization of the study: Nine recreationally-active men and women completed a treadmill-running graded exercise test (GXT) weekly (excepting wk 8) for 14 weeks. During the fi rst 3 and last 3 weeks, no quercetin supplementation was administered. During weeks 4-11, subjects ingested four soft Q-chews (Nutravail Technologies) per day containing quercetin (1 g/d), vitamin C, vitamin B3 and folic acid. A control group of 5 men were also tested during the fi rst and last week. Research results: VO2peak and test time remained stable throughout the 14 weeks at approximately 3.5±1.1 L/min and 6±1.6 min. Using a one-way repeated measures ANOVA, there was no signifi cant diff erence among means (P > 0.05) for either measure. Th ere was no trend for individual or mean values to increase above baseline during the treatment period. No changes occurred in the control group. Conclusions: We conclude that dietary quercetin supplementation with 1 g/d for 8 wk in non-endurance-trained men and women does not increase VO2peak or physical work capacity. Keywords: exercise, fl avonoids, muscle oxidative capacity, oxygen consumption


1964 ◽  
Vol 19 (6) ◽  
pp. 1114-1118 ◽  
Author(s):  
Bengt Saltin

Ten subjects performed standard exercise tests at two submaximal loads and one maximal load before and 90 min after dehydration caused predominantly by 1) a thermal, 2) a metabolic, and 3) a combined thermal and metabolic heat load applied for 2.5@#X2013;4 hr. Each subject interrupted dehydration so that almost the same decrease in body weight was attained in the three situations (1.7@#X2013;4.6 kg). Oxygen uptake, heart rate, and concentration of blood lactate were measured during the exercise. At the submaximal loads there was no change in oxygen uptake after dehydration but the heart rates were significantly higher (mean difference 13 beats/min) and blood lactates were lower (from 0.5 after (1) to 1.6 (2) mmoles/liter). At the maximal load there were no significant changes in oxygen uptake and heart rate but work times decreased markedly (6@#X2013;4 min) as did blood lactates (14.0@#X2013;10.4 mmoles/liter) especially after exercise dehydration. physical work capacity Submitted on January 20, 1964


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