The Stress of Lung Aging: Endoplasmic Reticulum and Senescence Tête-à-Tête
Keyword(s):
Beyond the structural changes, features including the dysregulation of endoplasmic reticulum (ER) stress response and increased senescence characterize the lung aging. ER stress response and senescence have been reported to be induced by factors like cigarette smoke. Therefore, deciphering the mechanisms underlying ER and senescent pathways interaction has become a challenge. In this review we highlight the known and unknown regarding ER stress response and senescence and their cross talk in aged lung.
2011 ◽
Vol 108
(22)
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pp. 9119-9124
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2014 ◽
Vol 289
(32)
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pp. 22090-22102
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2008 ◽
Vol 283
(25)
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pp. 17020-17029
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2019 ◽
Vol 2019
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pp. 1-13
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2010 ◽
Vol 340
(2)
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pp. 335-346
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2012 ◽
Vol 303
(1)
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pp. G54-G59
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