scholarly journals Limited potential of genetic predisposition scores to predict muscle mass and strength performance in Flemish Caucasians between 19 and 73 years of age

2017 ◽  
Vol 49 (3) ◽  
pp. 160-166 ◽  
Author(s):  
Ruben Charlier ◽  
Maarten Caspers ◽  
Sara Knaeps ◽  
Evelien Mertens ◽  
Diether Lambrechts ◽  
...  
Keyword(s):  
Muscle Mass ◽  
Genetic Predisposition ◽  
First Generation ◽  
Policy Research ◽  
Bioelectrical Impedance ◽  
Elastic Net ◽  
Movement Speed ◽  
Research Centre ◽  
Knee Extensors ◽  
Strength Performance

Since both muscle mass and strength performance are polygenic in nature, the current study compared four genetic predisposition scores (GPS) in their ability to predict these phenotypes. Data were gathered within the framework of the first-generation Flemish Policy Research Centre “Sport, Physical Activity and Health” (2002–2004). Results are based on muscle characteristics data of 565 Flemish Caucasians (19–73 yr, 365 men). Skeletal muscle mass was determined from bioelectrical impedance. The Biodex dynamometer was used to measure isometric (PTstatic120°) and isokinetic strength (PTdynamic60° and PTdynamic240°), ballistic movement speed (S20%), and muscular endurance (Work) of the knee extensors. Genotyping was done for 153 gene variants, selected on the basis of a literature search and the expression quantitative trait loci of selected genes. Four GPS were designed: a total GPS (based on the sum of all 153 variants, each favorable allele = score 1), a data-driven and weighted GPS [respectively, the sum of favorable alleles of those variants with significant b-coefficients in stepwise regression (GPSdd), and the sum of these variants weighted with their respective partial r2 (GPSw)], and an elastic net GPS (based on the variants that were selected by an elastic net regularization; GPSen). It was found that four different models for a GPS were able to significantly predict up to ~7% of the variance in strength performance. GPSen made the best prediction of SMM and Work. However, this was not the case for the remaining strength performance parameters, where best predictions were made by GPSdd and GPSw.

Relationship between trunk muscle strength and trunk muscle mass and thickness using bioelectrical impedance analysis and ultrasound imaging

2021 ◽  
pp. 1-10
Author(s):  
Ryo Miyachi ◽  
Nana Koike ◽  
Suzu Kodama ◽  
Junya Miyazaki
Keyword(s):  
Muscle Strength ◽  
Muscle Mass ◽  
Ultrasound Imaging ◽  
Bioelectrical Impedance Analysis ◽  
Muscle Thickness ◽  
Bioelectrical Impedance ◽  
Impedance Analysis ◽  
Trunk Muscle ◽  
Trunk Muscles ◽  
Trunk Muscle Strength

BACKGROUND: Although trunk muscles are involved in many important functions, evaluating trunk muscle strength is not an easy task. If trunk muscle mass and thickness could be used as indicators of trunk muscle strength, the burden of measurement would be reduced, but the relationship between trunk muscle strength and trunk muscle mass and thickness has not been clarified. OBJECTIVE: The purpose of this study was to clarify the relationship between trunk muscle strength and trunk muscle mass by bioelectrical impedance analysis and trunk muscle thickness by ultrasound imaging in healthy adults. METHODS: One hundred and twenty-one healthy university students were included in this study. Trunk flexion/extension muscle strength and trunk muscle mass by bioelectrical impedance analysis, and trunk muscle thickness by ultrasound imaging were measured. RESULTS: Both trunk flexion strength and trunk extension strength were significantly correlated with trunk muscle mass and oblique and rectus abdominis muscle thickness. Multiple regression analysis showed that trunk extension muscle strength had an independent relationship with trunk muscle mass. CONCLUSIONS: This study demonstrated that trunk muscle mass or trunk muscle thickness can be used as an alternative means for evaluating trunk muscle strength, making the evaluation of trunk muscles less burdensome.

scholarly journals Gender-specific analysis for the association between trunk muscle mass and spinal pathologies

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Yusuke Hori ◽  
Masatoshi Hoshino ◽  
Kazuhide Inage ◽  
Masayuki Miyagi ◽  
Shinji Takahashi ◽  
...  
Keyword(s):  
Muscle Mass ◽  
Bioelectrical Impedance ◽  
Vertical Axis ◽  
Impedance Analysis ◽  
Poor Quality ◽  
Trunk Muscle ◽  
Sagittal Vertical Axis ◽  
Cross Sectional ◽  
Lower Trunk ◽  
Significant Difference

AbstractWe investigated the relationship between trunk muscle mass and spinal pathologies by gender. This multicenter cross-sectional study included patients aged ≥ 30 years who visited a spinal outpatient clinic. Trunk and appendicular muscle mass were measured using bioelectrical impedance analysis. The Oswestry Disability Index (ODI), visual analog scale (VAS) score for low back pain, sagittal vertical axis (SVA), and EuroQol 5 Dimension (EQ5D) score were investigated to evaluate spinal pathology. The association between trunk muscle mass and these parameters was analyzed by gender using a non-linear regression model adjusted for patients’ demographics. We investigated the association between age and trunk muscle mass. We included 781 men and 957 women. Trunk muscle mass differed significantly between men and women, although it decreased with age after age 70 in both genders. Lower trunk muscle mass was significantly associated with ODI, SVA, and EQ5D score deterioration in both genders; its association with VAS was significant only in men. Most parameters deteriorated when trunk muscle mass was < 26 kg in men and < 19 kg in women. Lower trunk muscle mass was associated with lumbar disability, spinal imbalance, and poor quality of life in both genders, with significant difference in muscle mass.

Association between raw bioelectrical impedance parameters and muscle mass and strength measured by DXA and dynamometry in older adults: a pilot study

Nutrire ◽  
2021 ◽  
Vol 46 (1) ◽  
Author(s):  
Julia Miller da Fonseca Baldini ◽  
Shirley Steffany Muñoz Fernández ◽  
Sandra Maria Lima Ribeiro
Keyword(s):  
Older Adults ◽  
Pilot Study ◽  
Muscle Mass ◽  
Bioelectrical Impedance ◽  
Impedance Parameters

CNTF genotype is associated with muscular strength and quality in humans across the adult age span

2001 ◽  
Vol 90 (4) ◽  
pp. 1205-1210 ◽  
Author(s):  
Stephen M. Roth ◽  
Matthew A. Schrager ◽  
Robert E. Ferrell ◽  
Steven E. Riechman ◽  
E. Jeffrey Metter ◽  
...  
Keyword(s):  
Muscle Mass ◽  
Body Mass ◽  
Muscular Strength ◽  
Peak Torque ◽  
Fat Free Mass ◽  
Muscle Quality ◽  
Knee Extensors ◽  
Muscular Power ◽  
Adult Age ◽  
The Relationship

The relationship between ciliary neurotrophic factor (CNTF) genotype and muscle strength was examined in 494 healthy men and women across the entire adult age span (20–90 yr). Concentric (Con) and eccentric (Ecc) peak torque were assessed using a Kin-Com isokinetic dynamometer for the knee extensors (KE) and knee flexors (KF) at slow (0.52 rad/s) and faster (3.14 rad/s) velocities. The results were covaried for age, gender, and body mass or fat-free mass (FFM). Individuals heterozygous for the CNTF null (A allele) mutation (G/A) exhibited significantly higher Con peak torque of the KE and KF at 3.14 rad/s than G/G homozygotes when age, gender, and body mass were covaried ( P < 0.05). When the dominant leg FFM (estimated muscle mass) was used in place of body mass as a covariate, Con peak torque of the KE at 3.14 rad/s was also significantly greater in the G/A individuals ( P < 0.05). In addition, muscle quality of the KE (peak torque at 3.14 rad · s−1 · leg muscle mass−1) was significantly greater in the G/A heterozygotes ( P < 0.05). Similar results were seen in a subanalysis of subjects 60 yr and older, as well as in Caucasian subjects. In contrast, A/A homozygotes demonstrated significantly lower Ecc peak torque at 0.52 rad/s for both KE and KF compared with G/G and G/A groups ( P < 0.05). No significant relationships were observed at 0.52 rad/s between genotype and Con peak torque. These data indicate that individuals exhibiting the G/A genotype possess significantly greater muscular strength and muscle quality at relatively fast contraction speeds than do G/G individuals. Because of high positive correlations between fast-velocity peak torque and muscular power, these findings suggest that further investigations should address the relationship between CNTF genotype and muscular power.

Performance of a Novel Handheld Bioelectrical Impedance Device for Assessing Muscle Mass in Older Inpatients

2021 ◽  
pp. 1-7
Author(s):  
A.K. Stuck ◽  
A. Weber ◽  
R. Wittwer ◽  
A. Limacher ◽  
R.W. Kressig
Keyword(s):  
Muscle Mass ◽  
Bioelectrical Impedance ◽  
Impedance Analysis ◽  
Cross Sectional Study ◽  
Mean Difference ◽  
Second Phase ◽  
Cross Sectional ◽  
Rehabilitation Hospital ◽  
Appendicular Skeletal Muscle ◽  
Older Inpatients

Objectives: To investigate practicality and repeatability of a handheld compared to a state-of-the-art multisegmental bioelectrical impedance analysis (BIA) device to facilitate screening of sarcopenia in older inpatients. Design and setting: Cross-sectional study in a geriatric rehabilitation hospital. Participants: 207 inpatients aged 70+. Measurements: In a first phase, appendicular skeletal muscle mass index (ASMI) was measured using the handheld Biody xpertZm II BIA device (n=100). In a second phase, ASMI was obtained using the multisegmental Biacorpus RX 4004M device (n=107). Repeatability of BIA devices was compared in subgroups of patients (handheld BIA device: n=36, multisegmental BIA device: n=46) by intra-class correlation (ICC) and Bland-Altman plots. Results: Overall, measurement failure was seen in 31 patients (31%) tested with the handheld BIA device compared to one patient (0.9%) using the multisegmental BIA device (p<0.001). Main reasons for measurement failure were inability of patients to adopt the position necessary to use the handheld BIA device and device failure. The mean difference of two ASMI measurements in the same patient was 0.32 (sd 0.85) using the handheld BIA device compared to 0.02 kg/m2 (sd 0.07) using the multisegmental device (adjusted mean difference between both groups -0.35, 95% confidence interval (CI) -0.61 to -0.09 kg/m2). Congruently, Bland-Altman plots showed poor agreement with the handheld compared to the multisegmental BIA device. Conclusion: The handheld BIA device is neither a practical nor reliable device for assessing muscle mass in older rehabilitation inpatients.

scholarly journals Identifying critically ill patients with low muscle mass: Agreement between bioelectrical impedance analysis and computed tomography

2020 ◽  
Vol 39 (6) ◽  
pp. 1809-1817 ◽  
Author(s):  
Willem G.P.M. Looijaard ◽  
Sandra N. Stapel ◽  
Ingeborg M. Dekker ◽  
Hanna Rusticus ◽  
Sharon Remmelzwaal ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Critically Ill ◽  
Muscle Mass ◽  
Critically Ill Patients ◽  
Bioelectrical Impedance Analysis ◽  
Bioelectrical Impedance ◽  
Impedance Analysis
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