scholarly journals Risk of Coinfection withChlamydia trachomatisandNeisseria Gonorrhoeaein Nova Scotia

2010 ◽  
Vol 21 (2) ◽  
pp. e84-e86 ◽  
Author(s):  
Kevin R Forward
Keyword(s):  
Nova Scotia ◽  
Chlamydia Trachomatis ◽  
Neisseria Gonorrhoeae ◽  
Treatment Decisions ◽  
Empirical Treatment ◽  
Prevalence Rates ◽  
Accession Number ◽  
Males And Females ◽  
Concurrent Testing

BACKGROUND: The frequency of Chlamydia trachomatis and Neisseria gonorrhoeae coinfection can vary depending on their individual incidence and prevalence rates.OBJECTIVE: To determine the frequency ofC trachomatisandN gonorrhoeaecoinfections by evaluating the results of testing in 2007 and 2008 to better inform testing and treatment decisions.METHODS: Specimens from the same patient submitted on the same day served as the basis for the present study. The age, sex and the source of the specimen were also linked to the accession number. Infection and coinfection rates were analyzed in both males and females.RESULTS: Concurrent testing was performed on 41,567 female specimens and 1827 male specimens, of which, 1495 female samples (3.6%) tested positive forC trachomatisinfection and 88 (0.2%) tested positive forN gonorrhoeaeinfections. Only 31 females were coinfected; however, for those between 11 and 25 years of age, 25 of 61 females (40.1%) withN gonorrhoeaeinfection also tested positive forC trachomatisinfection; conversely, 25 of 1248 females (2.0%) withC trachomatisinfection also tested positive forN gonorrhoeaeinfection. For males, 213 (11.7%) tested positive forC trachomatisinfection,and 59 (3.2%) tested positive forN gonorrhoeaeinfection. In 30 males withN gonorrhoeaebetween 11 and 25 years of age, and 149 males withC trachomatis,eight coinfections were observed (26.7% and 5.3%, respectively). Of those older than 25 years of age, only five of 905 men and six of 19,465 women were coinfected. None of the 10,935 women who were 30 years of age or older had coinfections.CONCLUSION: TheN gonorrhoeaecoinfection rate in males withC trachomatismay justify empirical antimicrobials; however, in females, the proportion of coinfected may not justify empirical treatment forN gonorrhoeaeinfection when theC trachomatistest is positive andN gonorrhoeaetesting has not been performed.

scholarly journals Prevalence of urogenital, anal, and pharyngeal infections with Chlamydia trachomatis, Neisseria gonorrhoeae, and Mycoplasma genitalium: a cross-sectional study in Reunion island

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
A. Calas ◽  
N. Zemali ◽  
G. Camuset ◽  
J. Jaubert ◽  
R. Manaquin ◽  
...  
Keyword(s):  
Chlamydia Trachomatis ◽  
Neisseria Gonorrhoeae ◽  
Mycoplasma Genitalium ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Transmitted Infection ◽  
Cross Sectional ◽  
Sexually Transmitted ◽  
Urogenital Infection ◽  
High Prevalence

Abstract Background Recommendations for sexually transmitted infection (STI) screening vary significantly across countries. This study evaluated the prevalence of urogenital and extragenital infections with Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), and Mycoplasma genitalium (MG) in patients visiting a French STI clinic in the Indian Ocean region to determine whether current STI screening practices should be updated. Methods This cross-sectional study examined all patients who visited the STI clinic between 2014 and 2015. Triplex polymerase chain reaction screening for CT, NG, and MG was performed on urine, vaginal, pharyngeal, and anal specimens (FTD Urethritis Basic Kit, Fast Track Diagnostics, Luxembourg). Results Of the 851 patients enrolled in the study, 367 were women (367/851, 43.2%) and 484 were men (484/851, 56.0%). Overall, 826 urogenital specimens (826/851, 97.1%), 606 pharyngeal specimens (606/851, 71.2%), and 127 anal specimens (127/851, 14.9%) were taken from enrolled patients. The prevalence of urogenital CT and MG was high in women ≤25 years (19/186, 10.21%; 5/186, 2.69%) and in men who have sex with women ≤30 years (16/212, 7.54%; 5/212, 2.36%). Among patients with urogenital CT infection, 13.7% (7/51) had urethritis. All patients with urogenital MG infection were asymptomatic. Men who have sex with men had a high prevalence of pharyngeal CT (2/45, 4.44%) and NG (3/44, 6.81%) and a high prevalence of anal CT (2/27, 7.41%), NG (2/27, 7.40%), and MG (1/27, 3.70%). After excluding patients with concomitant urogenital infection, extragenital infections with at least 1 of the 3 pathogens were found in 20 swabs (20/91, 21.9%) taken from 16 patients (16/81, 19.7%), all of them asymptomatic. Conclusions Routine multisite screening for CT, NG, and MG should be performed to mitigate the transmission of STIs in high-risk sexually active populations.

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