scholarly journals Birth Defects in Singleton versus Multiple ART Births in Japan (2004–2008)

2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
Syuichi Ooki
Keyword(s):  
Neonatal Mortality ◽  
Birth Defects ◽  
Reference Group ◽  
Reproductive Technology ◽  
Neonatal Mortality Rate ◽  
Early Neonatal Mortality ◽  
Number Of Children ◽  
Early Neonatal Mortality Rate ◽  
The Mean ◽  
The Impact

The purpose of the present study was to evaluate the relative risk (RR) of multiple births for birth defects after assisted reproductive technology (ART) using Japanese nationwide data from 2004 to 2008 with singletons as the reference group. In multiples compared to singletons, the percentage of birth defects per pregnancy were significantly higher (RR = 1.88, 95% confidence interval (CI) 1.60–2.13), the percentage of birth defects per live birth was not significantly higher (RR = 0.90, 95% CI 0.78–1.05 or RR = 0.94, 95% CI 0.81–1.10), and the early neonatal mortality rate was significantly higher (RR = 2.68, 95% CI 1.52–4.70 or RR = 2.80, 95% CI 1.60–4.92). The early neonatal mortality per 10,000 live births was slightly higher in ART (5.09) than in the general population (3.86). We concluded that the impact of birth defects after ART would be larger in families with multiples compared to families with singletons, since the mean number of children would be larger in the former.

scholarly journals Early neonatal mortality rate and the risk factors in Wangaya hospital

2016 ◽  
Vol 48 (5) ◽  
pp. 306
Author(s):  
Made Lndah Nastiti Utami Budha ◽  
Wayan Retayasa ◽  
Made Kardana
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Mortality Rate ◽  
Neonatal Mortality ◽  
Gestational Age ◽  
Neonatal Death ◽  
Early Neonatal Death ◽  
Neonatal Mortality Rate ◽  
Early Neonatal Mortality ◽  
Early Neonatal Mortality Rate

Background The first week of life of a neonate is a critical period.In Asia, early neonatal mortality rate remains high.Objective To investigate early neonatal mortality rate and the riskfactors in Wangaya Hospital.Methods A cross sectional study was carried out retrospectivelyon neonates registered at Perinatology Unit, Wangaya HospitalDenpasar, Bali since January 2006. The study was done fromOctober to November 2007. Data was obtained from medicalrecord, analyzed as univariate using chi-square test or Fisher'sexact test and multivariate logistic regression analysis model.Results Early neonatal mortality rate in Wangaya Hospital was 38.7per 1000 livebirths. Univariate analyses showed that there werefive significant risk factors of early neonatal death, i.e., respiratorydistress, asphyxia, birth weight less than 2500 grams, sepsis, andgestational age less than 3 7 weeks. Multivariate analysis showedthat those five variables were significant as risk factors of earlyneonatal death i.e., OR (95% confidence interval) for respiratorydistress: 16.8 (3.7 to 76.6)], asphyxia: 13.5 (6.1 to 29.9)], birthweight <2500 grams: 8.1 (3.3 to 19.9)], sepsis: 7.3 (3.1 to 17.1),and gestational age <37 weeks: 3.5 (1.6 to 7.8)].Conclusions Early neonatal mortality rate in Wangaya Hospitalremains high. Respiratory distress, asphyxia, birth weight <2500gram, sepsis, and gestational age <37 weeks were independent riskfactors of early neonatal death.

Influence of the wars in Croatia and Bosnia and Herzegovina on the incidence and outcome of singleton premature births in the Split University Hospital

Open Medicine ◽  
2008 ◽  
Vol 3 (2) ◽  
pp. 187-193 ◽  
Author(s):  
Ivana Pavlinac ◽  
Ana Marin ◽  
Maja Valić ◽  
Jelena Marušić ◽  
Damir Roje ◽  
...  
Keyword(s):  
Mortality Rate ◽  
Neonatal Mortality ◽  
Preterm Delivery ◽  
Bosnia And Herzegovina ◽  
University Hospital ◽  
Hospital Data ◽  
Neonatal Mortality Rate ◽  
Early Neonatal Mortality ◽  
Gynecology And Obstetrics ◽  
Early Neonatal Mortality Rate

AbstractTo investigate the influence of the wars in Croatia and Bosnia and Herzegovina on incidence and perinatal outcome of singleton preterm births at the Department of Gynecology and Obstetrics in the Split University Hospital. Data were collected by reviewing patients’ files at the Department of Gynecology and Obstetrics from three periods: the three years before the war (1988–1990), during the war (1992–1994), and after the war (1996–1998). A total of 2,358 patients’ files of singleton preterm delivery were analyzed. Singleton preterm delivery rate decreased during the war (5.02%) and post-war period (4.74%) compared to the pre-war period (6.19%). Stillbirth and early neonatal mortality rates of singleton premature babies significantly increased during the war to 226%, compared to 193% before the war and 134% after the war. Early neonatal mortality rate was 215% during the war, 209% in the pre-war period, and 156% after the war. Despite the continuous decrease in singleton preterm birth rate throughout the observed periods, the increase in stillbirth rate and early neonatal mortality rate during the war might have been caused by the war. This may be due to primary gynecological care being inadequate for many pregnant women.

scholarly journals Prospective study to explore changes in quality of care and perinatal outcomes after implementation of perinatal death audit in Uganda

BMJ Open ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. e027504
Author(s):  
Victoria Nakibuuka Kirabira ◽  
Mamuda Aminu ◽  
Juan Emmanuel Dewez ◽  
Romano Byaruhanga ◽  
Pius Okong ◽  
...  
Keyword(s):  
Mortality Rate ◽  
Neonatal Mortality ◽  
Perinatal Mortality ◽  
Perinatal Death ◽  
Perinatal Outcomes ◽  
Stillbirth Rate ◽  
Neonatal Mortality Rate ◽  
Neonatal Deaths ◽  
Early Neonatal Mortality ◽  
Early Neonatal Mortality Rate

ObjectiveTo assess the effects of perinatal death (PND) audit on perinatal outcomes in a tertiary hospital in Kampala.DesignInterrupted time series (ITS) analysis.SettingNsambya Hospital, Uganda.ParticipantsLive births and stillbirths.InterventionsPND audit.Primary and secondary outcome measuresPrimary outcomes: perinatal mortality rate, stillbirth rate, early neonatal mortality rate. Secondary outcomes: case fatality rates (CFR) for asphyxia, complications of prematurity and neonatal sepsis.Results526 PNDs were audited: 142 (27.0%) fresh stillbirths, 125 (23.8%) macerated stillbirths and 259 (49.2%) early neonatal deaths. The ITS analysis showed a decrease in perinatal death (PND) rates without the introduction of PND audits (incidence risk ratio (IRR) (95% CI) for time=0.94, p<0.001), but an increase in PND (IRR (95% CI)=1.17 (1.0 to –1.34), p=0.0021) following the intervention. However, when overdispersion was included in the model, there were no statistically significant differences in PND with or without the intervention (p=0.06 and p=0.44, respectively). Stillbirth rates exhibited a similar pattern. By contrast, early neonatal death rates showed an overall upward trend without the intervention (IRR (95% CI)=1.09 (1.01 to 1.17), p=0.01), but a decrease following the introduction of the PND audits (IRR (95% CI)=0.35 (0.22 to 0.56), p<0.001), when overdispersion was included. The CFR for prematurity showed a downward trend over time (IRR (95% CI)=0.94 (0.88 to 0.99), p=0.04) but not for the intervention. With regards CFRs for intrapartum-related hypoxia or infection, no statistically significant effect was detected for either time or the intervention.ConclusionThe introduction of PND audit showed no statistically significant effect on perinatal mortality or stillbirth rate, but a significant decrease in early neonatal mortality rate. No effect was detected on CFRs for prematurity, intrapartum-related hypoxia or infections. These findings should encourage more research to assess the effectiveness of PND reviews on perinatal deaths in general, but also on stillbirths and neonatal deaths in particular, in low-resource settings.

The Mortality of Extremely Premature Infants and the Impact on the Overall Neonatal Mortality Rate [20C]

2016 ◽  
Vol 127 ◽  
pp. 31S
Author(s):  
Horatio S. Falciglia ◽  
William K. Brady ◽  
Ronald Merkel ◽  
Vickie Glover ◽  
Angela N. Fellner
Keyword(s):  
Mortality Rate ◽  
Neonatal Mortality ◽  
Premature Infants ◽  
Neonatal Mortality Rate ◽  
The Impact

scholarly journals Evaluation of vaginal birth safety in twin pregnancies with the first twin in cephalic presentation

2021 ◽  
Vol 3 (3) ◽  
pp. 59-63
Author(s):  
Bekir Kahveci ◽  
Mehmet Sukru Budak ◽  
Ihsan Baglı ◽  
Sedat Akgol
Keyword(s):  
Neonatal Mortality ◽  
Vaginal Birth ◽  
Neonatal Outcomes ◽  
Cesarean Birth ◽  
Early Neonatal Mortality ◽  
Mode Of Birth ◽  
Adverse Neonatal Outcomes ◽  
Early Neonatal Mortality Rate ◽  
Vertex Presentation ◽  
Twin Pregnancies

Objective: To evaluate vaginal birth safety by comparing the results of cesarean birth in twin pregnancies with the first twin in vertex presentation. Material and methods: A retrospective cohort study of vertex-presenting twin pregnancies between 32 weeks 0 days and 38 weeks 6 days of gestation was conducted at our hospital from January 2013 to December 2014. The study population was divided according to the mode of birth. The primary outcome was early neonatal mortality, and secondary outcomes related to maternal and perinatal clinical characteristics were analysed between the groups. Results: Of 45,166 births, 1.92% (n = 869) were twin pregnancies. Of the 295 pregnancies meeting the study criteria, 30.16% (n = 89) were in the vaginal birth group, while the remaining 69.84% (n = 206) were in the cesarean birth group. In the vaginal birth group, all the first twins were delivered via vaginal birth, while among the second twins, 82.03% (n = 73) were delivered via vaginal birth, and the remaining 17.97% (n = 16) were delivered via cesarean birth. In the vaginal birth group, the early neonatal mortality rate was 22.4‰ (n = 2), and it was 9.7‰ (n = 2) in the cesarean birth group. All of the deaths occurred in pregnancies under 37 weeks of gestation. Conclusion: The neonatal outcomes between the vaginal birth and cesarean birth groups were similar in term pregnancies with the first in twin vertex presentation, whereas adverse neonatal outcomes were increased in the vaginal birth group in preterm second twin pregnancies.

scholarly journals Gender variations in neonatal and early infant mortality in India and Pakistan: a secondary analysis from the Global Network Maternal Newborn Health Registry

2020 ◽  
Vol 17 (S3) ◽  
Author(s):  
Zubair H. Aghai ◽  
Shivaprasad S. Goudar ◽  
Archana Patel ◽  
Sarah Saleem ◽  
Sangappa M. Dhaded ◽  
...  
Keyword(s):  
Neonatal Mortality ◽  
Secondary Analysis ◽  
Newborn Health ◽  
Global Network ◽  
Live Births ◽  
Early Neonatal Mortality ◽  
Specific Mortality ◽  
Health Registry ◽  
Gender Variations ◽  
The Impact

Abstract Background To determine the gender differences in neonatal mortality, stillbirths, and perinatal mortality in south Asia using the Global Network data from the Maternal Newborn Health Registry. Methods This study is a secondary analysis of prospectively collected data from the three south Asian sites of the Global Network. The maternal and neonatal demographic, clinical characteristics, rates of stillbirths, early neonatal mortality (1–7 days), late neonatal mortality (8–28 days), mortality between 29–42 days and the number of infants hospitalized after birth were compared between the male and female infants. Results Between 2010 and 2018, 297,509 births [154,790 males (52.03%) and 142,719 females (47.97%)] from two Indian sites and one Pakistani site were included in the analysis [288,859 live births (97.1%) and 8,648 stillbirths (2.9%)]. The neonatal mortality rate was significantly higher in male infants (33.2/1,000 live births) compared to their female counterparts (27.4/1,000, p < 0.001). The rates of stillbirths (31.0 vs. 26.9/1000 births) and early neonatal mortality (27.1 vs 21.6/1000 live births) were also higher in males. However, there were no significant differences in late neonatal mortality (6.3 vs. 5.9/1000 live births) and mortality between 29–42 days (2.1 vs. 1.9/1000 live births) between the two groups. More male infants were hospitalized within 42 days after birth (1.8/1000 vs. 1.3/1000 live births, p < 0.001) than females. Conclusion The risks of stillbirths, and early neonatal mortality were higher among male infants than their female counterparts. However, there was no gender difference in mortality after 7 days of age. Our results highlight the importance of stratifying neonatal mortality into early and late neonatal period to better understand the impact of gender on neonatal mortality. The information from this study will help in developing strategies and identifying measures that can reduce differences in sex-specific mortality.

scholarly journals Neonatal Mortality in Two Tertiary Pediatric Hospitals in Baghdad (2012-2016)

2018 ◽  
Vol 59 (4) ◽  
pp. 330-332
Author(s):  
Hasanein A. Jawad ◽  
Eman A. Al-kaseer ◽  
Jawad KA Al-Diwan
Keyword(s):  
Neonatal Mortality ◽  
Neonatal Intensive Care ◽  
Cross Sectional Study ◽  
Neonatal Intensive Care Units ◽  
Sectional Study ◽  
Neonatal Mortality Rate ◽  
Cross Sectional ◽  
Pediatric Hospitals ◽  
The Impact ◽  
The Relationship

number of neonatal mortality rate (NMR). This study was conducted to clarify the relationship between conflict and neonatal mortality in Baghdad, Iraq.Objective: Throw a light on the impact of conflicts on neonatal mortality in Iraq.Methods: This cross-sectional study was carried out in two hospitals in Baghdad that were chosen randomly. All deceased newborns in neonatal intensive care units from January 2012 to December 2016 in the mentioned hospitals were included in this study.Results: The admissions were increased during the period of the study by 1.3 times. There was a decrease in admission by 0.9 in 2016 than 2015. There was an increase in NMR during the period of the study by 1.4 times, from 60/1000 in 2012 to 85/1000 in 2016.Conclusions: There has been an observed increase in neonatal mortality in Iraq due to the impact of conflicts that have led to deterioration in the neonatal health status. الخلفية: ربطت تقارير عديدة بين انتشار العنف والنزاعات المسلحة وزيادة معدلات وفيات حديثي الولادة. اجريت هذه الدراسة لتوضيح العلاقة بين النزاعات ووفيات الاطفال حديثي الولادة في بغداد، العراق. الاهداف: بيان مدى تأثير النزاعات على وفيات الأطفال حديثي الولادة في بغداد، العراق. الطرائق: أجريت هذه الدراسة المقطعية في مستشفيين في بغداد تم اختيار بشكل عشوائي. وقد شملت هذه الدراسة جميع المواليد حديثي الولادة في وحدات العناية المركزة لحديثي الولادة من كانون الثاني / يناير 2012 إلى كانون الأول / ديسمبر 2016 في المستشفيات المذكورة. النتائج: ازداد ادخال المواليد الجدد الى العناية المركزة بمقدار ١٫٣ مرة خلال فترة الدراسة. قل ادخال المواليد بمقدار ٠٫٩ في ٢٠١٦ عن السنة السابقة. نسبة وفيات المواليد الجدد ازدادت بمقدار ١٫٤ مرة خلال فترة الدراسة. نسبة وفيات المواليد الجدد كانت ٦٠ لكل ١٠٠٠ ولادة حية في العام ٢٠١٢ وأصبحت ٨٥ لكل ١٠٠٠ ولادة حية في العام ٢٠١٦. الاستنتاج: حدثت زيادة ملحوظة في وفيات المواليد الجدد في العراق بسبب تأثير النزاعات التي أدت إلى تدهور الوضع الصحي لحديثي الولادة.  

scholarly journals Neonatal Mortality is Modulated by Gestational Age, Birthweight and Fetal Heart Rate Abnormalities in the Low Resource Setting in Tanzania – a Five Year Review 2015-2019

2021 ◽  
Author(s):  
Aisa Shayo ◽  
Pendo Mlay ◽  
Emily Ahn ◽  
Hussein Kidanto ◽  
Michael Espiritu ◽  
...  
Keyword(s):  
Heart Rate ◽  
Mortality Rate ◽  
Neonatal Mortality ◽  
Fetal Heart Rate ◽  
Fetal Heart ◽  
Delivery Room ◽  
Moderate Hypothermia ◽  
Neonatal Mortality Rate ◽  
Low Resource ◽  
The Impact

Abstract Background Neonatal mortality (NM) remains a significant problem in low resource settings. Birth asphyxia (BA) and prematurity contribute significantly to NM. The study objectives were to determine first, the overall NM as well as yearly neonatal mortality rate from 2015 to 2019. Second, the impact of decreasing GA (<37 weeks) and BW (<2500 grams) on NM. Third, the contribution of intrapartum and delivery room (DR) factors and in particular fetal heart rate abnormalities (FHRT) on NM <7 days. Methods Retrospective cohort study. Labor and delivery room data were obtained from 2015 to 2019 and included BW, GA, fetal heart rate (FHRT) abnormalities, bag mask ventilation (BMV) during resuscitation, initial temperature, antenatal steroids use. Outcome was binary i.e. either death < 7 days or survival. Analysis included t tests, odds ratios (OR) and multiple logistic regression Results The overall neonatal mortality rate was 18/1000 livebirths over the five years. NM was significantly higher for newborns <37 versus ≥37 weeks, OR 10.5 (p<0.0001) and BW <2500 versus ≥2500g OR 9.9 (p<0.0001). For infants <1000g / <28 weeks, the neonatal mortality rate was ~ 588/1000 livebirths. Variables associated with NM included BW - odds of death decreased by 0.55 for every 500g increase in weight, by 0.89 for every week increase in GA, NM increased 6.8-fold with BMV, 2.6-fold with abnormal FHRT, 2.2 fold with no antenatal corticosteroid (ACS), 2.6-fold with moderate hypothermia (all <0.0001). Conclusion NM rates was predominantly modulated by decreasing BW and GA, with smaller/ less mature newborns 10-fold more likely to die. NM in term newborns is strongly associated with FHRT abnormalities and when coupled with respiratory depression suggests BA. In smaller newborns, lack of ACS and moderate hypothermia were additional contributing factors. A composite perinatal approach is essential to achieve a sustained reduction in NM.

Reduction in Perinatal Mortality after Implementation of HBB Training at a District Hospital in Mali

2019 ◽  
Vol 66 (3) ◽  
pp. 315-321
Author(s):  
M Innerdal ◽  
I Simaga ◽  
H Diall ◽  
M Eielsen ◽  
S Niermeyer ◽  
...  
Keyword(s):  
Mortality Rate ◽  
Neonatal Mortality ◽  
Perinatal Mortality ◽  
District Hospital ◽  
Neonatal Mortality Rate ◽  
Neonatal Deaths ◽  
Live Births ◽  
Early Neonatal Mortality ◽  
Helping Babies Breathe ◽  
Before And After

Abstract Background Mali has a high neonatal mortality rate of 38/1000 live births; in addition the fresh stillbirth rate (FSR) is 23/1000 births and of these one-third are caused by intrapartum events. Objectives The aims are to evaluate the effect of helping babies breathe (HBB) on mortality rate at a district hospital in Kati district, Mali. Methods HBB first edition was implemented in April 2016. One year later the birth attendants were trained in HBB second edition and started frequent repetition training. This is a before and after study comparing the perinatal mortality during the period before HBB training with the period after HBB training, the period after HBB first edition and the period after HBB second edition. Perinatal mortality is defined as FSR plus neonatal deaths in the first 24 h of life. Results There was a significant reduction in perinatal mortality rate (PMR) between the period before and after HBB training, from 21.7/1000 births to 6.0/1000 live births; RR 0.27, (95% CI 0.19–0.41; p &lt; 0.0001). Very early neonatal mortality rate (24 h) decreased significantly from 6.3/1000 to 0.8/1000 live births; RR 0.12 (95% CI 0.05–0.33; p = 0.0006). FSR decreased from 15.7/1000 to 5.3/1000, RR 0.33 (95% CI 0.22–0.52; p &lt; 0.0001). No further reduction occurred after introducing the HBB second edition. Conclusion HBB may be effective in a local first-level referral hospital in Mali.

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