scholarly journals Development of Ultrasonic Modulation Probe for Fluorescence Tomography Based on Acousto-Optic Effect

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Trinh Quang Duc ◽  
Shunsuke Kaneta ◽  
Masaki Kobayashi

We have developed an ultrasonic probe for fluorescence modulation to image fluorescence within biological tissues. The probe consists of a focused ultrasonic transducer mounted on actuators for mechanical fan scanning, which can be used in contact with the measuring object aiming for clinical application. The mechanical fan scanning employed in the probe has a beneficial feature of portability. As a result, fluorescent beads, which were localized with the diameter of 2 mm at 20 mm depth in a pork meat tissue, were detected with resolution of 3 mm. The system performance denotes the feasibility of development towards the final goal of ultrasonic fluorescence modulation tomography for clinical applications.

Micromachines ◽  
2018 ◽  
Vol 9 (11) ◽  
pp. 584 ◽  
Author(s):  
Changho Lee ◽  
Jin Kim ◽  
Chulhong Kim

Photoacoustic imaging (PAI) is a new biomedical imaging technology currently in the spotlight providing a hybrid contrast mechanism and excellent spatial resolution in the biological tissues. It has been extensively studied for preclinical and clinical applications taking advantage of its ability to provide anatomical and functional information of live bodies noninvasively. Recently, microelectromechanical systems (MEMS) technologies, particularly actuators and sensors, have contributed to improving the PAI system performance, further expanding the research fields. This review introduces cutting-edge MEMS technologies for PAI and summarizes the recent advances of scanning mirrors and detectors in MEMS.


1986 ◽  
Vol 25 (06) ◽  
pp. 220-224 ◽  
Author(s):  
G. L. Buraggi

A review of the studies on the use of the antigen-antibody system HMW-MAA 225.28S in melanoma radioimmunodetection is reported. The results obtained in a pilot study (42 patients with 74 lesions), a multicenter trial (254 patients with 553 lesions) and a prospective study still outstanding (29 patients with 38 lesions) allow to consider this system as suitable for clinical application. F(ab′)2 labelled with 99mTc gave the best results in terms of positivity. Moreover this radioisotope allows the best dosimetric conditions. The gamma energy emitted by this radionuclide is particularly convenient for conventional scintillation cameras and ECT. Very good results in terms of sensitivity (70%-85%) and especially specificity (about 100%) were achieved. Possible clinical applications of the method are discussed.


Author(s):  
Florian A. Huber ◽  
Roman Guggenberger

AbstractRecent investigations have focused on the clinical application of artificial intelligence (AI) for tasks specifically addressing the musculoskeletal imaging routine. Several AI applications have been dedicated to optimizing the radiology value chain in spine imaging, independent from modality or specific application. This review aims to summarize the status quo and future perspective regarding utilization of AI for spine imaging. First, the basics of AI concepts are clarified. Second, the different tasks and use cases for AI applications in spine imaging are discussed and illustrated by examples. Finally, the authors of this review present their personal perception of AI in daily imaging and discuss future chances and challenges that come along with AI-based solutions.


PEDIATRICS ◽  
1950 ◽  
Vol 6 (5) ◽  
pp. 825-825

In the field of physical medicine there is need for a book which will outline the principles underlying therapeutic exercise, and which will give definite examples of their clinical application. The physiologic foundation for many of the clinical applications of exercises is not too firm, so that a book which would be able to relate the principles of exercise to the fundamental underlying physiologic principles would be a most valuable one. The author attempts to do this in the first part of this book, which is called "Fundamental Working Principles."


1975 ◽  
Vol 6 (1-2) ◽  
pp. 255-265 ◽  
Author(s):  
Peter P. Hauri

The parameters amenable to biofeedback learning are mentioned, including brainwaves, muscle tension, temperature, the cardiovascular system, and others. A discussion follows of the clinical application of biofeedback in the treatment of such disorders as tension headaches, neuromuscular re-education, epilepsy, “dysponesis,” cardiac arrhythmias, blood pressure and migraines. The usefulness of biofeedback has been demonstrated also in the field of psychotherapy for purposes of desensitization, treating anxious patients, encouraging specific personality changes, and indicating stress to patients.


2000 ◽  
Author(s):  
Xinwei Wang ◽  
Xianfan Xu ◽  
Lisa X. Xu

Abstract Ultrafast (or ultrashort) pulsed laser ablation of biological tissue has drawn much attention due to the minimal collateral damage caused by laser irradiation. Many clinical applications of ultrafast laser ablation have been proposed, including ophthalmology, dentistry, and neurosurgery (Kim et al., 1998). During ultrafast laser interaction with biological tissues, which are dielectric materials, multiphonon absorption occurs which enhances the absorption of the laser beam in tissue. The tissue can then be heated rapidly to a high temperature, causing evaporation and tissue removal.


2009 ◽  
Vol 02 (01) ◽  
pp. 73-92 ◽  
Author(s):  
ZHENG HUANG ◽  
LIBO LI ◽  
HONGWEI WANG ◽  
XIULI WANG ◽  
KAIHUA YUAN ◽  
...  

Photodynamic therapy (PDT) has received increased attention since the regulatory approvals of several photosensitizers and light applicators in numerous countries and regions around the world. In recent years, much progress has been seen in basic research as well as clinical application. PDT clinical application has now extended from treating malignant diseases to nonmalignant diseases. This review article will present recent clinical data published in English journals. The data will be organized according to their clinical specialties. The new development and future direction in clinical applications of PDT for the management of both malignant and nonmalignant diseases will be discussed.


2006 ◽  
Vol 49 ◽  
pp. 14-20
Author(s):  
Egbert Brandau ◽  
Thorsten Brandau

Clinical applications of Calcium phosphate compounds are done in most cases with powders of Calcium-tri-phosphate and/or Hydroxylapatite to enhance the surgery of orthopaedic repair. The application of microspheres of these compounds has big advantages to faster surgery and higher strength of the bone structure. The special processes to produce microspheres of narrow size distribution and high sphericity out Calcium-tri-phosphate and Hydroxylapatite are described. Properties and composition of these microspheres as calcined and as sintered are given.


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